Article
Clinical Neurology
Mickael L. D. Deroche, Jace Wolfe, Sara Neumann, Jacy Manning, William Towler, Razieh Alemi, Alexander G. Bien, Nabin Koirala, Lindsay Hanna, Lauren Henry, Vincent L. Gracco
Summary: This study investigated the use of auditory evoked potentials as markers of auditory processing in children with cochlear implants. The results showed that this method could differentiate children based on their language and literacy abilities, and potentially serve as a clinical tool for tracking developmental outcomes.
CLINICAL NEUROPHYSIOLOGY
(2023)
Article
Physiology
Chihiro Mori, Kazuo Okanoya
Summary: Learning sound patterns and detecting deviant patterns are important behaviors in animals. This study explores the characterization of mismatch negativity (MMN) in the Java sparrow, a vocal learning bird. The results suggest that MMN-like responses in the oddball task may reflect adaptation to repeated standard sounds rather than genuine deviance detection. Furthermore, the study demonstrates the ability of the songbird to extract sound sequence information.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Multidisciplinary Sciences
Vasco Ribeiro Ferreira, Ana Rita Pereira, Joana Vieira, Frederico Pereira, Rui Marques, Guilherme Campos, Adriana Sampaio, Alberto Crego
Summary: Clinical auditory alarms in hospital environments need to be designed to convey priority without compromising other features. This study found that the Medium Priority pulse of the updated IEC60601-1-8 standard is more easily detected and attended at the neural level compared to the High Priority pulse. Behavioral experiments also showed shorter reaction times for the Medium Priority pulse. The study highlights the need for intervention in hospital soundscapes and auditory alarm design settings.
Article
Audiology & Speech-Language Pathology
Timm Rosburg, Ralph Mager
Summary: The amplitude of the auditory evoked N1 component depends on the interstimulus interval, increasing with longer intervals until saturating around 10 seconds. The conflicting accounts of N1 recovery and habituation predict different outcomes for passive oddball experiments, with evidence suggesting that N1 refractoriness may play a more significant role in explaining stimulus repetition effects.
Article
Neurosciences
Zachary J. Williams, Peter G. Abdelmessih, Alexandra P. Key, Tiffany G. Woynaroski
Summary: Autistic individuals show multiple alterations in early cortical auditory processing of simple stimuli compared to typically developing control subjects, such as prolonged latencies and reduced amplitudes. However, most group differences are modest in size and based on small numbers of heterogeneous studies with variable quality.
BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING
(2021)
Article
Clinical Neurology
Xu Ding, Huihua Fang, Yutong Liu, Lin Zheng, Xiangru Zhu, Hongxia Duan, Jianhui Wu
Summary: This study aimed to explore the relationship between trait resilience and bottom-up automatic information processing in healthy adults. The results showed that higher resilience was associated with slower automatic detection speed and lower sensory sensitivity.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Biochemistry & Molecular Biology
Bshara Awwad, Maciej M. Jankowski, Ana Polterovich, Sapir Bashari, Israel Nelken
Summary: The article discusses the relationship between unexpected changes in sensory streams and prediction errors in deviant stimulus. It explores the association between Mismatch Negativity (MMN) and Stimulus-Specific Adaptation (SSA) in humans and animals. Research findings show that violation of expectations due to unexpected stimulus omission can elicit omission MMN. These responses reflect temporal expectancy and are often time locked to the end of the omitted stimulus. The study also demonstrates the occurrence of offset responses in the auditory cortex of unanesthetized rats, which contribute to a rich and varied representation of prediction-related signals.
Article
Psychology, Biological
Kelin M. Brace, Elyse S. Sussman
Summary: This study investigated the role of explicit knowledge in modulating how sounds are represented in auditory memory, and found that even without explicit knowledge, listeners are able to maintain representations of multiple sound organizations in auditory memory, indicating that explicit knowledge is not a necessary factor in complex sound environments.
Article
Neurosciences
Maria Bader, Erich Schroger, Sabine Grimm
Summary: The study using event-related potentials found that the auditory system can extract implicit regularities even in the presence of acoustic distortions, although distortions led to decreased amplitude of mismatch negativity and P3a. Wrong-pitch distortions had a larger impact on P3a amplitude compared to white-noise distortions, likely due to interference with relevant pattern information.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Neurosciences
Haruka Ochiai, Tetsuya Shiga, Hiroshi Hoshino, Sho Horikoshi, Kazuko Kanno, Tomohiro Wada, Yusuke Osakabe, Itaru Miura, Hirooki Yabe
Summary: This study aimed to investigate the impact of oxytocin nasal spray on auditory MMN, with results showing significantly shorter MMN latencies in participants who received oxytocin compared to those who received a placebo. However, oxytocin did not have a significant effect on the change in MMN amplitude.
PSYCHOPHARMACOLOGY
(2021)
Article
Neurosciences
Francoise Lecaignard, Olivier Bertrand, Anne Caclin, Jeremie Mattout
Summary: This study transforms the question of the complementarity of EEG and MEG for source reconstruction from a general theoretical issue to a practical empirical one, focusing on evaluating multimodal data fusion on real data. The proposed approach utilizes Parametric Empirical Bayes' flexibility for EEG-MEG data fusion and formal hypothesis testing, demonstrating the advantages of multimodal inference, the greater spatial sensitivity of MEG compared to EEG, and the ability of EEG to reconstruct temporal lobe activity on its own.
Article
Clinical Neurology
Bernd Feige, Chiara Baglioni, Philipp Boehm, Anna Heinrich, Samuel Trumm, Fee Benz, Christoph Nissen, Katharina Domschke, Lukas Frase, Dieter Riemann
Summary: The study found a reduced P2 amplitude in insomnia patients during phasic REM sleep, which was correlated with sleep misperception. Independent component analysis showed that frontal negativity played a key role in this group difference.
Article
Neurosciences
GuiSen Wu, XiaoChen Tang, RanPiao Gan, JiaHui Zeng, YeGang Hu, LiHua Xu, YanYan Wei, YingYing Tang, Tao Chen, HaiChun Liu, ChunBo Li, JiJun Wang, TianHong Zhang
Summary: Individuals at clinical high risk for psychosis exhibit dysfunctions in pre-attentive deviance processing, as indicated by compromised mismatch negativity (MMN) response. This study investigated the association between event-related potential and time-frequency information with clinical profiles in CHR individuals, and identified predictive indices for remission. The findings suggest disrupted automatic auditory processing in certain CHR subtypes and the potential of MMN response as a neurophysiological marker for distinct clinical subtypes.
HUMAN BRAIN MAPPING
(2022)
Article
Biology
Lilian Aline Weber, Sara Tomiello, Dario Schobi, Katharina Wellstein, Daniel Mueller, Sandra Iglesias, Klaas Enno Stephan
Summary: The study aimed to test whether auditory mismatch responses are sensitive to the enhancing and diminishing effects of cholinergic and dopaminergic function, and found differential effects of drugs on mismatch responses, which may be useful for predicting treatment responses in schizophrenia.
Article
Neurosciences
Kelin M. Brace, Elyse S. Sussman
Summary: The study investigated how the brain maintains rhythmic predictions in the presence of multiple perceptual interpretations from the same sound source. Results showed that the brain can track multiple predictions about complexities in sound streams and automatically detect deviations with respect to these predictions.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Substance Abuse
Jonatan Ottino-Gonzalez, Hugh Garavan, Matthew D. Albaugh, Zhipeng Cao, Renata B. Cupertino, Nathan Schwab, Philip A. Spechler, Nicholas Allen, Eric Artiges, Tobias Banaschewski, Arun L. W. Bokde, Erin Burke Quinlan, Ruediger Bruehl, Catherine Orr, Janna Cousijn, Sylvane Desrivieres, Herta Flor, John J. Foxe, Juliane H. Froehner, Anna E. Goudriaan, Penny Gowland, Antoine Grigis, Andreas Heinz, Robert Hester, Kent Hutchison, Chiang-Shan R. Li, Edythe D. London, Valentina Lorenzetti, Maartje Luijten, Frauke Nees, Rocio Martin-Santos, Jean-Luc Martinot, Sabina Millenet, Reza Momenan, Marie-Laure Paillere Martinot, Dimitri Papadopoulos Orfanos, Martin P. Paulus, Luise Poustka, Lianne Schmaal, Gunter Schumann, Rajita Sinha, Michael N. Smolka, Nadia Solowij, Dan J. Stein, Elliot A. Stein, Anne Uhlmann, Ruth J. Holst, Dick J. Veltman, Henrik Walter, Robert Whelan, Reinout W. Wiers, Murat Yucel, Sheng Zhang, Neda Jahanshad, Paul M. Thompson, Patricia Conrod, Scott Mackey
Summary: Graph theoretic analysis of structural covariance networks provides insights into brain organization in alcohol dependence. This study found that a specific structural covariance network profile can serve as an early marker for alcohol dependence in adults, and may also be a pre-existing risk factor for problematic drinking.
Article
Psychiatry
Ana A. Francisco, John J. Foxe, Douwe J. Horsthuis, Sophie Molholm
Summary: We investigated visual processing and adaptation in individuals with 22q11.2 deletion syndrome, a condition associated with an increased risk for schizophrenia. Our findings suggest that there are differences in early visual processing and adaptation between individuals with 22q11.2 deletion syndrome and those with idiopathic schizophrenia. The results indicate that there may be specific neurogenetic aspects associated with the deletion in chromosome 22 and that visual processing measures in the later time window may be markers of psychosis presence and chronicity/severity.
Article
Neurosciences
Eleni Patelaki, John J. Foxe, Kevin A. Mazurek, Edward G. Freedman
Summary: This study investigates the effects of pairing a cognitive task with walking in young adults. The preliminary findings suggest that some participants improve in cognitive task performance while walking, while others do not. Neural activity changes associated with performance improvement may have potential implications for assessing cognitive decline in aging and neurodegeneration.
Article
Genetics & Heredity
Emily J. Knight, Aaron Krakowski, Edward G. Freedman, John S. Butler, Sophie Molholm, John J. Foxe
Summary: This study examined the modulating role of attention in biological motion processing in ASD, finding that individuals with ASD have reduced automatic neural specificity for upright biological motion compared to neurotypical individuals, but are able to discriminate biological from non-biological motion with explicit attention. Additionally, distinctive patterns of covariance were observed between visual potentials evoked by biological motion and functional social ability in the ASD group, suggesting potential implications for the development of higher-order social cognition.
Article
Biology
Michael J. Crosse, John J. Foxe, Katy Tarrit, Edward G. Freedman, Sophie Molholm
Summary: The study reveals that deficits in multisensory processing observed in high-functioning children and teenagers with autism spectrum disorders (ASD) are not evident in adults with the disorder. Computational modelling shows a delayed transition of multisensory processing from competition to facilitation in ASD. The findings highlight the complex and dynamic interplay among sensory systems that differ in individuals with ASD.
COMMUNICATIONS BIOLOGY
(2022)
Article
Neurosciences
Lars A. Ross, Sophie Molholm, John S. Butler, Victor A. Del Bene, John J. Foxe
Summary: This fMRI study investigated the effect of observing articulatory movements while listening to a narrative stimulus. The results showed that under synchronous audiovisual conditions, there was multisensory enhancement in various regions of the language network, including the integration of auditory and visual information. The study also found involvement of regions related to extralinguistic sensory and cognitive processing.
Article
Neurosciences
Daniel A. Lopez, Zachary P. Christensen, John J. Foxe, Laura R. Ziemer, Paige R. Nicklas, Edward G. Freedman
Summary: The study found that children who experienced possible mTBI or mTBI are at a higher risk of emotional or behavioral problems. However, brain metrics did not clearly mediate the relationship between mTBI and mental health outcomes.
Article
Neurosciences
Kathryn-Mary Wakim, Edward G. Freedman, Madalina E. Tivarus, Zachary Christensen, Sophie Molholm, John J. Foxe
Summary: This exploratory study examined the combinatorial effects of HIV and cocaine dependence (CD) history on brain morphology and neurocognitive performance. The results showed no evidence of compounded differences in neurocognitive function or structural measures of brain integrity in HIV+ individuals in recovery from CD relative to individuals with only one condition.
Article
Neurosciences
Kathryn-Mary Wakim, John J. Foxe, Sophie Molholm
Summary: Motor atypicalities are common in autism spectrum disorder (ASD) and research on basic motor processing in autistic individuals is surprisingly sparse. In this study, we analyzed EEG data from a large sample of autistic and neurotypical children and adolescents, revealing clear motor-related neural responses in ASD, but with subtle differences compared to typically developing participants. Group differences were most prominent in the youngest group of children (age 6-9), suggesting the need for further investigations in younger children.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Emily J. Knight, Edward G. Freedman, Evan J. Myers, Alaina S. Berruti, Leona A. Oakes, Cody Zhewei Cao, Sophie Molholm, John J. Foxe
Summary: Individuals with autism spectrum disorder exhibit atypical sensory perception, which is not fully understood. One proposed mechanism is an imbalance in higher-order feedback inputs during sensory perception, resulting in a preference for local object features. This study investigated this theory using visual evoked potentials and found that autistic children had attenuated responses to illusory contours compared to neurotypical controls. These findings suggest that weakened predictive feedback processes may contribute to the visual processing anomalies seen in autism.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Eleni Patelaki, John J. Foxe, Emma P. Mantel, George Kassis, Edward G. Freedman
Summary: Combining walking with a cognitive task can improve performance in younger and older adults, with the former benefiting cognitively while the latter experiencing motor decline. EEG activity and behavioral responses during walking were correlated with increased response accuracy, while slower walking speeds and changes in EEG activity were associated with aging.
Editorial Material
Neurosciences
Michael Willis, Megan R. Carey, John J. Foxe, Jackie Jones, Nathan Smith, Vidita Vaidya
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Eleni Patelaki, John J. Foxe, Amber L. McFerren, Edward G. Freedman
Summary: This study investigates the neural mechanisms underlying increased cognitive load while walking. The findings suggest that the difficulty of the cognitive task does not affect response accuracy, speed, or gait consistency, but it does lead to changes in EEG components.
Article
Neurosciences
Emily L. Isenstein, Edward G. Freedman, Jiayi Xu, Ian A. DeAndrea-Lazarus, John J. Foxe
Summary: This study evaluated electrophysiological discrimination of parametric somatosensory stimuli in healthy young adults to understand how the brain processes the duration of tactile information. The results showed that participants did not electrophysiologically discriminate between 100 and 115 ms, but they exhibited distinct electrophysiological responses when the deviant stimuli were 130, 145, and 160 ms. These findings contribute to a better understanding of tactile sensitivity in different clinical conditions.