Prophylactic treatment against GM-CSF, but not IL-17, abolishes relapses in a chronic murine model of multiple sclerosis

Targeting the GM-CSF receptor for the treatment of CNS autoimmunity

(2017) Igal Ifergan et al.   JOURNAL OF AUTOIMMUNITY

GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System–Infiltrating Cells, but Is Dispensable for Disease Induction

(2017) Patrick C. Duncker et al.   JOURNAL OF IMMUNOLOGY

IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression

(2017) Giacomo Casella et al.   Scientific Reports

Activity of secukinumab, an anti-IL-17A antibody, on brain lesions in RRMS: results from a randomized, proof-of-concept study

(2016) Eva Havrdová et al.   JOURNAL OF NEUROLOGY

GM-CSF-Producing Th Cells in Rats Sensitive and Resistant to Experimental Autoimmune Encephalomyelitis

(2016) Zorica Stojić-Vukanić et al.   PLoS One

Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy

(2015) Javad Rasouli et al.   JOURNAL OF IMMUNOLOGY

GM-CSF in Neuroinflammation: Licensing Myeloid Cells for Tissue Damage

(2015) Andrew L. Croxford et al.   TRENDS IN IMMUNOLOGY

Immunology of Relapse and Remission in Multiple Sclerosis

(2014) Lawrence Steinman   Annual Review of Immunology

STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation

(2014) Wanqiang Sheng et al.   CELL RESEARCH

GM-CSF-Responsive Monocyte-Derived Dendritic Cells Are Pivotal in Th17 Pathogenesis

(2014) H.-J. Ko et al.   JOURNAL OF IMMUNOLOGY

Defining the clinical course of multiple sclerosis: The 2013 revisions

(2014) F. D. Lublin et al.   NEUROLOGY

Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells

(2014) Felix J. Hartmann et al.   Nature Communications

Anti–IL-17A Treatment Reduces Clinical Score and VCAM-1 Expression Detected by in Vivo Magnetic Resonance Imaging in Chronic Relapsing EAE ABH Mice

(2013) Silvy Mardiguian et al.   AMERICAN JOURNAL OF PATHOLOGY

Cutting Edge: The Pathogenicity of IFN- -Producing Th17 Cells Is Independent of T-bet

(2013) R. Duhen et al.   JOURNAL OF IMMUNOLOGY

Upregulation of IL-17, but not of IL-9, in circulating cells of CIS and relapsing MS patients. Impact of corticosteroid therapy on the cytokine network

(2012) Nathalie Muls et al.   JOURNAL OF NEUROIMMUNOLOGY

Amine-reactive OVA multimers for auto-vaccination against cytokines and other mediators: perspectives illustrated for GCP-2 in L. major infection

(2011) Catherine Uyttenhove et al.   JOURNAL OF LEUKOCYTE BIOLOGY

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

(2011) Mohamed El-Behi et al.   NATURE IMMUNOLOGY

EAE mediated by a non-IFN-γ/non-IL-17 pathway

(2010) Mark A. Kroenke et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Current Views on the Roles of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

(2010) Mohamed El-behi et al.   Journal of Neuroimmune Pharmacology

GM-CSF mediates autoimmunity by enhancing IL-6–dependent Th17 cell development and survival

(2008) Ivo Sonderegger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

(2007) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY