Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms

The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway

(2013) Edina Schweighoffer et al.   IMMUNITY

Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy

(2013) Cheng Liao et al.   ARTHRITIS RESEARCH & THERAPY

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state

(2012) Sebastian Königsberger et al.   EMBO JOURNAL

B Cell Receptor Signal Transduction in the GC Is Short-Circuited by High Phosphatase Activity

(2012) A. M. Khalil et al.   SCIENCE

Regulation of Developmental Lymphangiogenesis by Syk+ Leukocytes

(2010) Ruben Böhmer et al.   DEVELOPMENTAL CELL

The dissociation activation model of B cell antigen receptor triggering

(2010) Jianying Yang et al.   FEBS LETTERS

Visualizing a role for the actin cytoskeleton in the regulation of B-cell activation

(2010) Facundo D. Batista et al.   IMMUNOLOGICAL REVIEWS

Therapeutic Targeting of Syk in Autoimmune Diabetes

(2010) L. Colonna et al.   JOURNAL OF IMMUNOLOGY

Autoinhibition and adapter function of Syk

(2009) Yogesh Kulathu et al.   IMMUNOLOGICAL REVIEWS

Antibody diversification by somatic mutation: from Burnet onwards

(2008) Michael S Neuberger   IMMUNOLOGY AND CELL BIOLOGY