Swiprosin-1/EFhd2 limits germinal center responses and humoral type 2 immunity

Regulatory constraints in the generation and differentiation of IgE-expressing B cells

(2014) Zhiyong Yang et al.   CURRENT OPINION IN IMMUNOLOGY

Swiprosin-1 modulates actin dynamics by regulating the F-actin accessibility to cofilin

(2013) Yun Hyun Huh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Intrinsic T- and B-cell defects impair T-cell-dependent antibody responses in mice lacking the actin-bundling protein L-plastin

(2013) Elizabeth M. Todd et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The distinctive germinal center phase of IgE + B lymphocytes limits their contribution to the classical memory response

(2013) Jin-Shu He et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dose-Dependent Induction of Murine Th1/Th2 Responses to Sheep Red Blood Cells Occurs in Two Steps: Antigen Presentation during Second Encounter Is Decisive

(2013) Claudia Stamm et al.   PLoS One

Swiprosin-1 Expression Is Up-Regulated through Protein Kinase C-θ and NF-κB Pathway in T Cells

(2013) Young-Dae Kim et al.   Immune Network

B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice

(2012) M. Recher et al.   BLOOD

The B cell receptor-induced calcium flux involves a calcium mediated positive feedback loop

(2012) Sandra Hagen et al.   CELL CALCIUM

Fluorescent In Vivo Detection Reveals that IgE+ B Cells Are Restrained by an Intrinsic Cell Fate Predisposition

(2012) Zhiyong Yang et al.   IMMUNITY

IgE+ memory B cells and plasma cells generated through a germinal-center pathway

(2012) Oezcan Talay et al.   NATURE IMMUNOLOGY

B Cell Receptor Signal Transduction in the GC Is Short-Circuited by High Phosphatase Activity

(2012) A. M. Khalil et al.   SCIENCE

Fraternal twins: Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1, two homologous EF-hand containing calcium binding adaptor proteins with distinct functions

(2011) Sebastian Dütting et al.   Cell Communication and Signaling

Antibody-Mediated Coengagement of FcγRIIb and B Cell Receptor Complex Suppresses Humoral Immunity in Systemic Lupus Erythematosus

(2011) Holly M. Horton et al.   JOURNAL OF IMMUNOLOGY

Cofilin-Mediated F-Actin Severing Is Regulated by the Rap GTPase and Controls the Cytoskeletal Dynamics That Drive Lymphocyte Spreading and BCR Microcluster Formation

(2011) S. A. Freeman et al.   JOURNAL OF IMMUNOLOGY

B Cells: From Early Development to Regulating Allergic Diseases

(2010) Konstantinos Samitas et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Basophils Orchestrate Chronic Allergic Dermatitis and Protective Immunity against Helminths

(2010) Caspar Ohnmacht et al.   IMMUNITY

T cells and follicular dendritic cells in germinal center B-cell formation and selection

(2010) Carola G. Vinuesa et al.   IMMUNOLOGICAL REVIEWS

Swiprosin-1/EFhd2 Controls B Cell Receptor Signaling through the Assembly of the B Cell Receptor, Syk, and Phospholipase C  2 in Membrane Rafts

(2010) C. Kroczek et al.   JOURNAL OF IMMUNOLOGY

Limited humoral immunoglobulin E memory influences serum immunoglobulin E levels in blood

(2009) G. Achatz-Straussberger et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Swiprosin-1 is expressed in mast cells and up-regulated through the protein kinase CβI/η pathway

(2009) Ramesh P. Thylur et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production

(2009) Katrina L Randall et al.   NATURE IMMUNOLOGY

Checkpoints in lymphocyte development and autoimmune disease

(2009) Harald von Boehmer et al.   NATURE IMMUNOLOGY

Migration of antibody secreting cells towards CXCL12 depends on the isotype that forms the BCR

(2008) Gertrude Achatz-Straussberger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Helminth infections: the great neglected tropical diseases

(2008) Peter J. Hotez et al.   JOURNAL OF CLINICAL INVESTIGATION