Cytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNA

Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids

(2014) Jiaxi Wu et al.   Annual Review of Immunology

Activation of the STING Adaptor Attenuates Experimental Autoimmune Encephalitis

(2014) H. Lemos et al.   JOURNAL OF IMMUNOLOGY

Marginal zone CD169+ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance

(2014) B. Ravishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STING-Dependent Type I IFN Production Inhibits Cell-Mediated Immunity to Listeria monocytogenes

(2014) Kristina A. Archer et al.   PLoS Pathogens

Adverse events during the titration phase of interferon-beta in remitting-relapsing multiple sclerosis are not predicted by body mass index nor by pharmacodynamic biomarkers

(2013) Delicias Muñoz et al.   BMC Neurology

Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling

(2013) Hiroyasu Konno et al.   CELL

Metabolic control of tumour progression and antitumour immunity

(2013) Lei Huang et al.   CURRENT OPINION IN ONCOLOGY

Recognition of cytosolic DNA by cGAS and other STING-dependent sensors

(2013) Numana Bhat et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immune Sensing of DNA

(2013) Søren R. Paludan et al.   IMMUNITY

The interferon response to intracellular DNA: Why so many receptors?

(2013) Leonie Unterholzner   IMMUNOBIOLOGY

The Interdependent, Overlapping, and Differential Roles of Type I and II IFNs in the Pathogenesis of Experimental Autoimmune Encephalomyelitis

(2013) R. Naves et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: DNA Sensing via the STING Adaptor in Myeloid Dendritic Cells Induces Potent Tolerogenic Responses

(2013) L. Huang et al.   JOURNAL OF IMMUNOLOGY

Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid

(2013) J. Conlon et al.   JOURNAL OF IMMUNOLOGY

MPYS/STING-Mediated TNF- , Not Type I IFN, Is Essential for the Mucosal Adjuvant Activity of (3'-5')-Cyclic-Di-Guanosine-Monophosphate In Vivo

(2013) S. M. Blaauboer et al.   JOURNAL OF IMMUNOLOGY

STING Recognition of Cytoplasmic DNA Instigates Cellular Defense

(2013) Takayuki Abe et al.   MOLECULAR CELL

The cGAS-STING Pathway for DNA Sensing

(2013) T. Sam Xiao et al.   MOLECULAR CELL

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

(2013) John W. Schoggins et al.   NATURE

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

CD8+ T Cells Are Required For Glatiramer Acetate Therapy in Autoimmune Demyelinating Disease

(2013) Andrew F. Tyler et al.   PLoS One

Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection

(2013) E. B. Wilson et al.   SCIENCE

Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling

(2013) J. R. Teijaro et al.   SCIENCE

Nucleic Acid Sensors and Type I Interferon Production in Systemic Lupus Erythematosus

(2013) Meena Shrivastav et al.   Frontiers in Immunology

Innate immune sensing of cancer: clues from an identified role for type I IFNs

(2012) Thomas F. Gajewski et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities

(2012) Peter M. Gray et al.   CELLULAR IMMUNOLOGY

Wounding the Immune System with its Own Blade: HIV-Induced Tryptophan Catabolism and Pathogenesis

(2012) A. Boasso   CURRENT MEDICINAL CHEMISTRY

Histo-Cytometry: A Method for Highly Multiplex Quantitative Tissue Imaging Analysis Applied to Dendritic Cell Subset Microanatomy in Lymph Nodes

(2012) Michael Y. Gerner et al.   IMMUNITY

Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease

(2012) Alevtina Gall et al.   IMMUNITY

Engineering DNA Nanoparticles as Immunomodulatory Reagents that Activate Regulatory T Cells

(2012) L. Huang et al.   JOURNAL OF IMMUNOLOGY

STING and the innate immune response to nucleic acids in the cytosol

(2012) Dara L Burdette et al.   NATURE IMMUNOLOGY

Essential contribution of IRF3 to intestinal homeostasis and microbiota-mediated Tslp gene induction

(2012) H. Negishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase

(2012) B. Ravishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STING manifests self DNA-dependent inflammatory disease

(2012) J. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Indoleamine 2,3 dioxygenase and metabolic control of immune responses

(2012) David H. Munn et al.   TRENDS IN IMMUNOLOGY

Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen

(2011) T. L. McGaha et al.   BLOOD

Physiologic Control of IDO Competence in Splenic Dendritic Cells

(2011) B. Baban et al.   JOURNAL OF IMMUNOLOGY

Opposing Biological Functions of Tryptophan Catabolizing Enzymes During Intracellular Infection

(2011) Senad Divanovic et al.   JOURNAL OF INFECTIOUS DISEASES

Leishmania major Attenuates Host Immunity by Stimulating Local Indoleamine 2,3-Dioxygenase Expression

(2011) Levi H. C. Makala et al.   JOURNAL OF INFECTIOUS DISEASES

STING is a direct innate immune sensor of cyclic di-GMP

(2011) Dara L. Burdette et al.   NATURE

TheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides

(2010) John-Demian Sauer et al.   INFECTION AND IMMUNITY

Dendritic Cells, Indoleamine 2,3 Dioxygenase and Acquired Immune Privilege

(2010) Lei Huang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

TLR9 Regulates TLR7- and MyD88-Dependent Autoantibody Production and Disease in a Murine Model of Lupus

(2010) Kevin M. Nickerson et al.   JOURNAL OF IMMUNOLOGY

SIGNR1-Negative Red Pulp Macrophages Protect against Acute Streptococcal Sepsis after Leishmania donovani-Induced Loss of Marginal Zone Macrophages

(2009) Alun C. Kirby et al.   AMERICAN JOURNAL OF PATHOLOGY

Antitumoral efficacy of DNA nanoparticles in murine models of lung cancer and pulmonary metastasis

(2009) M Rodrigo-Garzón et al.   CANCER GENE THERAPY

IDO Activates Regulatory T Cells and Blocks Their Conversion into Th17-Like T Cells

(2009) B. Baban et al.   JOURNAL OF IMMUNOLOGY