SDF1α-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells

Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation

(2014) Jatuporn Ngoenkam et al.   Cell Communication and Signaling

Relevance of Nck-CD3  Interaction for T Cell Activation In Vivo

(2014) A. Borroto et al.   JOURNAL OF IMMUNOLOGY

The adapter proteins ADAP and Nck cooperate in T cell adhesion

(2014) Marcus Lettau et al.   MOLECULAR IMMUNOLOGY

Targeting the LYN/HS1 signaling axis in chronic lymphocytic leukemia

(2013) E. ten Hacken et al.   BLOOD

Nck enables directional cell migration through the coordination of polarized membrane protrusion with adhesion dynamics

(2013) S. P. Chaki et al.   JOURNAL OF CELL SCIENCE

The Actin Regulatory Protein HS1 Interacts with Arp2/3 and Mediates Efficient Neutrophil Chemotaxis

(2012) Peter J. Cavnar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cortactin in cell migration and cancer at a glance

(2012) S. M. MacGrath et al.   JOURNAL OF CELL SCIENCE

Nck Recruitment to the TCR Required for ZAP70 Activation during Thymic Development

(2012) A. Borroto et al.   JOURNAL OF IMMUNOLOGY

High expression of hematopoietic cell specific Lyn substrate-1 (HS1) predicts poor survival of B-cell chronic lymphocytic leukemia patients

(2012) Aleksandra Butrym et al.   LEUKEMIA RESEARCH

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF–triggered granulopoiesis

(2012) Julia Skokowa et al.   NATURE MEDICINE

HS1, a Lyn Kinase Substrate, Is Abnormally Expressed in B-Chronic Lymphocytic Leukemia and Correlates with Response to Fludarabine-Based Regimen

(2012) Federica Frezzato et al.   PLoS One

Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo

(2011) Mélissa Labelle-Côté et al.   BMC CANCER

The Actin Regulatory Protein HS1 Is Required for Antigen Uptake and Presentation by Dendritic Cells

(2011) Y. Huang et al.   JOURNAL OF IMMUNOLOGY

HS1 has a central role in the trafficking and homing of leukemic B cells

(2010) C. Scielzo et al.   BLOOD

Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia

(2010) M. Oser et al.   JOURNAL OF CELL SCIENCE

The adapter protein Nck: Role of individual SH3 and SH2 binding modules for protein interactions in T lymphocytes

(2010) Marcus Lettau et al.   PROTEIN SCIENCE

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

Nck adapter proteins: functional versatility in T cells

(2009) Marcus Lettau et al.   Cell Communication and Signaling

Hematopoietic Lineage Cell-Specific Protein 1 Is Recruited to the Immunological Synapse by IL-2-Inducible T Cell Kinase and Regulates Phospholipase C 1 Microcluster Dynamics during T Cell Spreading

(2009) E. Carrizosa et al.   JOURNAL OF IMMUNOLOGY

The Actin Cytoskeleton in T Cell Activation

(2008) Janis K. Burkhardt et al.   Annual Review of Immunology

Differently phosphorylated forms of the cortactin homolog HS1 mediate distinct functions in natural killer cells

(2008) Boyd Butler et al.   NATURE IMMUNOLOGY

The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes

(2008) Michaël Mingueneau et al.   NATURE IMMUNOLOGY

Hematopoeitic lineage cell-specific protein-1 (HS1) regulates PAR-mediated ERK activation and thromboxane generation in platelets

(2008) Bryan N. Kahner et al.   PLATELETS