Extrathymic induction of Foxp3+regulatory T cells declines with age in a T-cell intrinsic manner

Th2 Lymphoproliferative Disorder of LatY136F Mutant Mice Unfolds Independently of TCR-MHC Engagement and Is Insensitive to the Action of Foxp3+ Regulatory T Cells

(2014) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

Retinoic Acid Hypersensitivity Promotes Peripheral Tolerance in Recent Thymic Emigrants

(2013) S. Bhaumik et al.   JOURNAL OF IMMUNOLOGY

Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery

(2013) R. S. Paiva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of the T cell in age-related inflammation

(2012) Richard Macaulay et al.   AGE

Extrathymic Generation of Regulatory T Cells in Placental Mammals Mitigates Maternal-Fetal Conflict

(2012) Robert M. Samstein et al.   CELL

Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans

(2012) Ineke den Braber et al.   IMMUNITY

Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice

(2012) Denise Tischner et al.   JOURNAL OF AUTOIMMUNITY

Foxp3 Expression Is Required for the Induction of Therapeutic Tissue Tolerance

(2012) F. S. Regateiro et al.   JOURNAL OF IMMUNOLOGY

Pregnancy imprints regulatory memory that sustains anergy to fetal antigen

(2012) Jared H. Rowe et al.   NATURE

Extrathymically generated regulatory T cells control mucosal TH2 inflammation

(2012) Steven Z. Josefowicz et al.   NATURE

The narrowing of the CD8 T cell repertoire in old age

(2011) Marcia A Blackman et al.   CURRENT OPINION IN IMMUNOLOGY

Sub-optimal CD4+ T-cell activation triggers autonomous TGF-β-dependent conversion to Foxp3+ regulatory T cells

(2011) Vanessa G. Oliveira et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Integrated T-cell receptor and costimulatory signals determine TGF-β-dependent differentiation and maintenance of Foxp3+ regulatory T cells

(2011) Leona Gabryšová et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Sustained suppression by Foxp3+regulatory T cells is vital for infectious transplantation tolerance

(2011) Adrian R. Kendal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Potentiation of Th17 cytokines in aging process contributes to the development of colitis

(2010) Xinshou Ouyang et al.   CELLULAR IMMUNOLOGY

TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo

(2010) Rachel A. Gottschalk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Major Role for Bim in Regulatory T Cell Homeostasis

(2010) C. A. Chougnet et al.   JOURNAL OF IMMUNOLOGY

Leukocyte function in the aging immune system

(2010) Anjali Desai et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Effects of aging on T cell function

(2009) Laura Haynes et al.   CURRENT OPINION IN IMMUNOLOGY

A Central Role for Induced Regulatory T Cells in Tolerance Induction in Experimental Colitis

(2009) D. Haribhai et al.   JOURNAL OF IMMUNOLOGY

Nuclear factor-κB-dependent reversal of aging-induced alterations in T cell cytokines

(2008) Mei-Chuan Huang et al.   FASEB JOURNAL

Retinoic Acid Enhances Foxp3 Induction Indirectly by Relieving Inhibition from CD4+CD44hi Cells

(2008) Jonathan A. Hill et al.   IMMUNITY

Antigen-specific peripheral shaping of the natural regulatory T cell population

(2008) Stephanie K. Lathrop et al.   JOURNAL OF EXPERIMENTAL MEDICINE