Regulation and dysregulation of innate immunity by NFAT signaling downstream of pattern recognition receptors (PRRs)

Cutting Edge: Notch Signaling Induces a Distinct Cytokine Profile in Dendritic Cells That Supports T Cell-Mediated Regulation and IL-2-Dependent IL-17 Production

(2014) L. Bugeon et al.   JOURNAL OF IMMUNOLOGY

CD14 and NFAT mediate lipopolysaccharide-induced skin edema formation in mice

(2012) Ivan Zanoni et al.   JOURNAL OF CLINICAL INVESTIGATION

Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5

(2012) Maria Buxadé et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection

(2012) Fei Chen et al.   NATURE MEDICINE

Cellular and Molecular Mechanisms of TSLP Function in Human Allergic Disorders - TSLP Programs the “Th2 code” in Dendritic Cells

(2012) Tomoki Ito et al.   ALLERGOLOGY INTERNATIONAL

IL-2 production by dendritic cells promotes Foxp3+regulatory T-cell expansion in autoimmune-resistant NOD congenic mice

(2011) Evridiki Sgouroudis et al.   AUTOIMMUNITY

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Nuclear presence of nuclear factor of activated T cells (NFAT) c3 and c4 is required for Toll-like receptor-activated innate inflammatory response of monocytes/macrophages

(2011) Hiroshi Minematsu et al.   CELLULAR SIGNALLING

CLEC-2 signaling via Syk in myeloid cells can regulate inflammatory responses

(2011) Diego Mourão-Sá et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Similarities and differences of innate immune responses elicited by smooth and rough LPS

(2011) Ivan Zanoni et al.   IMMUNOLOGY LETTERS

Proteinase-activated receptor 2 activation promotes an anti-inflammatory and alternatively activated phenotype in LPS-stimulated murine macrophages

(2011) Quan M Nhu et al.   Innate Immunity

Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes

(2011) Nora A. Barrett et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Protease-Activated Receptor 2 Is Involved in Th2 Responses againstTrichinella spiralisInfection

(2011) Mi Kyung Park et al.   KOREAN JOURNAL OF PARASITOLOGY

The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease

(2011) Zhihua Liu et al.   NATURE IMMUNOLOGY

A role for interleukin-2 trans-presentation in dendritic cell–mediated T cell activation in humans, as revealed by daclizumab therapy

(2011) Simone C Wuest et al.   NATURE MEDICINE

TNF activates calcium-nuclear factor of activated T cells (NFAT)c1 signaling pathways in human macrophages

(2011) A. Yarilina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcineurin regulates innate antifungal immunity in neutrophils

(2010) Matthew B. Greenblatt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Requirement of phospholipase C-γ2 (PLCγ2) for Dectin-1-induced antigen presentation and induction of TH1/TH17 polarization

(2009) Ilaria Tassi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Prostaglandin E2 at new glance: Novel insights in functional diversity offer therapeutic chances

(2009) Daniel F. Legler et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Expression of Diabetes-Associated Genes by Dendritic Cells and CD4 T Cells Drives the Loss of Tolerance in Nonobese Diabetic Mice

(2009) E. E. Hamilton-Williams et al.   JOURNAL OF IMMUNOLOGY

CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation

(2009) Ivan Zanoni et al.   NATURE

Migratory and Lymphoid-Resident Dendritic Cells Cooperate to Efficiently Prime Naive CD4 T cells

(2008) Eric J. Allenspach et al.   IMMUNITY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Inflammation and oxidative stress in vertebrate host-parasite systems

(2008) G. Sorci et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Turning NF-κB and IRFs on and off in DC

(2008) Tsuneyasu Kaisho et al.   TRENDS IN IMMUNOLOGY