Clinical and fundamental aspects of monocyte, macrophage and dendritic cell plasticity

Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell-expressed FasL

(2011) P. Sinha et al.   BLOOD

The 2011 Nobel Prize in Physiology or Medicine: Honor, sadness and lessons

(2011) Catherine Sautès-Fridman   EUROPEAN JOURNAL OF IMMUNOLOGY

A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation

(2011) Luke C. Davies et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Diversity and plasticity of mononuclear phagocytes

(2011) Siamon Gordon et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Intestinal Dendritic Cells Specialize to Activate Transforming Growth Factor-β and Induce Foxp3+ Regulatory T Cells via Integrin αvβ8

(2011) John J. Worthington et al.   GASTROENTEROLOGY

The Ubiquitin-Editing Protein A20 Prevents Dendritic Cell Activation, Recognition of Apoptotic Cells, and Systemic Autoimmunity

(2011) Mirjam Kool et al.   IMMUNITY

The Signaling Adaptor Eps8 Is an Essential Actin Capping Protein for Dendritic Cell Migration

(2011) Emanuela Frittoli et al.   IMMUNITY

Peroxisome Proliferator-Activated Receptor  -Regulated Cathepsin D Is Required for Lipid Antigen Presentation by Dendritic Cells

(2011) B. Nakken et al.   JOURNAL OF IMMUNOLOGY

Nifedipine Affects the Course of Salmonella enterica Serovar Typhimurium Infection by Modulating Macrophage Iron Homeostasis

(2011) Sabine M. Mair et al.   JOURNAL OF INFECTIOUS DISEASES

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

(2011) Mourad Matmati et al.   NATURE GENETICS

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

DNA released from dying host cells mediates aluminum adjuvant activity

(2011) Thomas Marichal et al.   NATURE MEDICINE

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Evolution of Th2 Immunity: A Rapid Repair Response to Tissue Destructive Pathogens

(2011) Judith E. Allen et al.   PLoS Pathogens

Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo

(2010) M. C. Bosco et al.   BLOOD

Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

(2010) K. Movahedi et al.   CANCER RESEARCH

The struggle for iron - a metal at the host-pathogen interface

(2010) Manfred Nairz et al.   CELLULAR MICROBIOLOGY

Some active areas of DC research and their medical potential

(2010) Ralph M. Steinman   EUROPEAN JOURNAL OF IMMUNOLOGY

The fractalkine receptor CX3CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes

(2010) Karlin Raja Karlmark et al.   HEPATOLOGY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Functional Contribution of Elevated Circulating and Hepatic Non-Classical CD14+CD16+ Monocytes to Inflammation and Human Liver Fibrosis

(2010) Henning W. Zimmermann et al.   PLoS One

Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

(2009) Karlin Raja Karlmark et al.   HEPATOLOGY

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor  B

(2009) C. Porta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MafB/c-Maf Deficiency Enables Self-Renewal of Differentiated Functional Macrophages

(2009) A. Aziz et al.   SCIENCE

Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice

(2009) Ravid Shechter et al.   PLOS MEDICINE

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

(2008) K. Movahedi et al.   BLOOD