Article
Endocrinology & Metabolism
Kristina Vabalayte, Anatoly Romanchishen, Aleksandra Somova
Summary: The study aimed to evaluate the effectiveness of ICG-angiography and intrathyroid injection of Brilliant Green in preventing postoperative hypoparathyroidism. The results showed that these methods are safe and effective in identifying and sparing the parathyroid glands, with a more prominent occurrence of hypocalcemia in the group with visually estimated PTG postoperatively.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Otorhinolaryngology
Shireen Samargandy, John Wadie, Haytham Msallak, Albino Chiodo, William El Masri, Bradley Hubbard, Danny Enepekides, Kevin Higgins, Angela Assal, Rebecca Fine, Raymond Fung, Everton Nicholas, Valrie Beadle, Antoine Eskander
Summary: This study aimed to develop a PTH-based protocol to predict hypocalcemia after thyroidectomy. The results showed that using postoperative PTH cut-offs can effectively predict hypocalcemia and reduce unnecessary calcium replacement and length of stay.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Article
Surgery
Fiona Riordan, Catherine Brophy, Matthew S. Murphy, Patrick Sheahan
Summary: Early parathyroid hormone (PTH) levels after total thyroidectomy can predict patients at low risk of hypocalcaemia who can be discharged early without calcium supplementation. PTH levels >= 15 pg/ml along with calcium >= 2.0 mmol/l are associated with low risk of symptomatic hypocalcaemia, and represent a safe criterion for discharge of most patients without calcium supplementation.
LANGENBECKS ARCHIVES OF SURGERY
(2022)
Article
Surgery
Hadiza S. Kazaure, Alan Zambeli-Ljepovic, Taofik Oyekunle, Sanziana A. Roman, Julie A. Sosa, Michael T. Stang, Randall P. Scheri
Summary: Severe post-thyroidectomy hypocalcemia is a common complication, with an incidence of approximately 5.8%. Patients who experience severe hypocalcemia are at higher risk of nerve injury and unplanned reoperations, indicating the impact of surgical complexity and provider experience on this complication.
Article
Surgery
Fiona Riordan, Matthew S. Murphy, Linda Feeley, Patrick Sheahan
Summary: Identifying more parathyroid glands during total thyroidectomy (TT) is associated with increased rates of biochemical and symptomatic hypocalcemia, but does not impact permanent hypoparathyroidism or incidental parathyroidectomy.
LANGENBECKS ARCHIVES OF SURGERY
(2022)
Article
Surgery
Charlotte Melot, Gabrielle Deniziaut, Fabrice Menegaux, Nathalie Chereau
Summary: This retrospective cohort study investigated the clinical relevance of avoidable incidental parathyroidectomy (IP) during thyroid surgery. The study found that avoidable IP was associated with a higher risk of transient hypocalcemia and permanent hypoparathyroidism. Central lymph node dissection and incidental removal of thymus tissue were identified as independent risk factors for IP.
Article
Endocrinology & Metabolism
Dengwei Lu, Enjie Tang, Supeng Yin, Junping Zhu, Hongbiao Mo, Ziying Yi, Fan Chai, Yizeng Sun, Yao Li, Tingjie Yin, Zeyu Yang, Fan Zhang
Summary: This retrospective cohort study aimed to investigate influential factors in the occurrence and restoration of postoperative hypoparathyroidism (POH) in thyroid cancer patients who underwent total thyroidectomy with intraoperative parathyroid autotransplantation (TTIPA). The study found that high postoperative fasting blood glucose levels, a large number of transplanted parathyroid glands, open surgery, and Hashimoto's thyroiditis are risk factors for postoperative POH. Female patients and patients without same-side central lymph node dissection (CLND) on the transplant side are more prone to increased PTH levels. Patients without CLND and those who underwent endoscopic surgery on the transplant side have a faster PTH restoration.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Emmanuel A. Mannoh, Giju Thomas, Naira Baregamian, Sarah L. Rohde, Carmen C. Solorzano, Anita Mahadevan-Jansen
Summary: Accurate assessment of parathyroid gland vascularity using LSCI is crucial in thyroidectomy. This study found that a speckle contrast value above 0.186 during surgery may be associated with low postoperative PTH levels.
Article
Endocrinology & Metabolism
Xiaozhou Cheng, Yaping Li, Lijun Chen
Summary: The purpose of this study was to evaluate the safety and efficacy of autologous parathyroid transplantation in laparoscopic total thyroidectomy combined with central lymph node dissection. The results showed that preserving the parathyroid glands during the surgery helped prevent hypoparathyroidism after the operation, and it was an effective strategy to prevent permanent hypoparathyroidism.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Surgery
D. Palmhag, J. Brydolf, J. Zedenius, R. Branstrom, I. -L. Nilsson
Summary: Measuring parathyroid hormone level 2 hours after thyroidectomy is an excellent indicator for predicting transient hypoparathyroidism, especially for patients with vitamin D sufficiency. Additionally, determining the perioperative decline in parathyroid hormone can provide added diagnostic value for certain patients with specific preoperative conditions.
SCANDINAVIAN JOURNAL OF SURGERY
(2021)
Article
Otorhinolaryngology
Eva Lykke, Anders Christensen, Karina Juhl, Ulla Feldt-Rasmussen, Mette Friberg Hitz, Sannia Mia Svenningsen Sjostedt, Christoffer Holst Hahn, Ditte Maria Kraik Svensson, Karoline Kanstrup Springborg, Mads Georg Stage, Gitte Bjorn Hvilsom, Linda Maria Hilsted, Morten Dahl, Giedrius Lelkaitis, Andreas Kjaer, Preben Homoe, Christian von Buchwald
Summary: The purpose of this study was to investigate whether near-infrared autofluorescence image guidance can reduce the incidence of hypoparathyroidism in total thyroidectomy. The results showed that near-infrared autofluorescence imaging can improve the detection rate of parathyroid glands and reduce the rate of hypoparathyroidism, but the difference was not statistically significant. Further studies are needed to confirm the use of near-infrared autofluorescence imaging as an auxiliary tool for parathyroid gland identification.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Endocrinology & Metabolism
Olivia A. A. Keane, Shasha Bai, Kristina Cossen, Briana C. C. Patterson, Kara K. K. Prickett, Kurt F. F. Heiss, Matthew T. T. Santore
Summary: This study aimed to predict the risk of permanent hypoparathyroidism (PH) in pediatric patients following total thyroidectomy by evaluating the post-operative parathyroid hormone (PTH) levels at 6 hours. Results showed that a PTH value ≤ 11.3 pg/mL at 6 hours post-operatively predicted the occurrence of PH.
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
(2023)
Article
Surgery
Pichit Sittitrai, Donyarat Ruenmarkkaew, Hanpon Klibngern, Tapanut Ariyanon, Nutthiya Hanprasertpong, Somkamon Boonyaprapa, Maysayawan Sreesawat
Summary: This study evaluated the efficacy of perioperative and postoperative calcium and vitamin D supplementation in reducing symptomatic hypocalcemia. The results showed that perioperative supplementation significantly decreased the occurrence of symptomatic hypocalcemia and shortened the recovery period, while there were no significant differences in other indicators between the two groups.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Article
Nutrition & Dietetics
Salvatore Tramontano, Gerardo Sarno, Pietro Calabrese, Luigi Schiavo, Maria Spagnuolo, Vincenzo Pilone
Summary: The risk of post-thyroidectomy hypocalcemia and hypoparathyroidism is similar between patients with a history of restrictive bariatric surgery and those without, suggesting that the timing or type of bariatric intervention does not significantly increase the risk of developing these complications.
Article
Medicine, General & Internal
Abdullah Saeed Abdullah
Summary: Measuring serum PTH levels 3 hours after thyroid surgery can accurately predict the development of hypocalcemia, guiding early intervention with calcium and/or vitamin D supplements for high-risk patients with PTH levels below 10 pg/ml. Patients with PTH levels above 10 pg/ml may be safely discharged early without any supplements. Further studies are needed to compare early serum PTH levels with day one serum PTH levels post total thyroidectomy to predict hypocalcemia.
ANNALS OF MEDICINE AND SURGERY
(2021)
Article
Surgery
Luke Nankee, Herbert Chen, David F. Schneider, Rebecca S. Sippel, Dawn M. Elfenbein
JOURNAL OF SURGICAL RESEARCH
(2015)
Article
Pediatrics
Dawn M. Elfenbein, Micah Katz, David F. Schneider, Herbert Chen, Rebecca S. Sippel
JOURNAL OF PEDIATRIC SURGERY
(2016)
Article
Surgery
Areg Grigorian, Nii-Kabu Kabutey, Sebastian Schubl, Christian de Virgilio, Victor Joe, Matthew Dolich, Dawn Elfenbein, Jeffry Nahmias
Article
Oncology
Dawn M. Elfenbein, Sara Weber, David F. Schneider, Rebecca S. Sippel, Herbert Chen
ANNALS OF SURGICAL ONCOLOGY
(2015)
Article
Surgery
Nick A. Zaborek, Andy Cheng, Joseph R. Imbus, Kristin L. Long, Susan C. Pitt, Rebecca S. Sippel, David F. Schneider
Article
Surgery
Dean Spencer, Areg Grigorian, Sebastian Schubl, Kyrillos Awad, Dawn Elfenbein, Taimoore Dogar, Jeffry Nahmias
JOURNAL OF SURGICAL RESEARCH
(2019)
Article
Surgery
Stephen S. Chen, Nick A. Zaborek, Amanda R. Doubleday, Sarah C. Schaefer, Kristin L. Long, Susan C. Pitt, Rebecca S. Sippel, David F. Schneider
JOURNAL OF SURGICAL RESEARCH
(2019)
Article
Surgery
Siddique Akram, Dawn M. Elfenbein, Herbert Chen, David F. Schneider, Rebecca S. Sippel
JOURNAL OF SURGICAL RESEARCH
(2020)
Article
Oncology
Priya H. Dedhia, Elizabeth M. Stoeckl, Alexandria D. McDow, Susan C. Pitt, David F. Schneider, Rebecca S. Sippel, Kristin L. Long
JOURNAL OF SURGICAL ONCOLOGY
(2020)
Article
Surgery
Amanda R. Doubleday, Sarah E. Robbins, Cameron L. Macdonald, Dawn M. Elfenbein, Nadine P. Connor, Rebecca S. Sippel
Summary: This study investigated the experience of patients with transient hypoparathyroidism after total thyroidectomy and found that although postoperative hypoparathyroidism was common, it did not have a substantial negative impact on the overall quality of life when appropriately managed.
Article
Education, Scientific Disciplines
Divya Ramakrishnan, Khanh Van Le-Bucklin, Tania Saba, Glen Leverson, Jun Hee Kim, Dawn M. Elfenbein
Summary: There is significant variability in the number of grading tiers used and the percentage of students awarded honors across US medical schools. Factors that correlated to higher grades included schools with higher rankings, and higher ranked schools were less likely to report comparative information at all.
JOURNAL OF SURGICAL EDUCATION
(2022)
Article
Surgery
William Duong, Areg Grigorian, Cyrus Farzaneh, Dawn Elfenbein, Maki Yamamoto, Kathryn Rosenbaum, Michael Lekawa, Jeffry Nahmias
Summary: This study demonstrates that intraoperative neuromonitoring (INM) during thyroidectomy is associated with a significant reduction in the odds of severe RLNi, with nearly 80% decreased odds.
AMERICAN JOURNAL OF SURGERY
(2022)
Article
Education, Scientific Disciplines
Joseph C. L. Huillier, Sarah L. Larson, Adam M. Awe, Dorothy S. Cook, Dawn M. Elfenbein
Summary: Medical students in surgical specialties who participate in a formalized mentorship program have more frequent mentor meetings and receive support in career guidance, letters of recommendation, and application preparation. However, compared to informal mentorship, the formal program may lack psychological and emotional support while providing more assistance in skills development.
JOURNAL OF SURGICAL EDUCATION
(2022)
Article
Surgery
Vivian Hsiao, Dawn M. Elfenbein, Susan C. Pitt, Kristin L. Long, Rebecca S. Sippel, David F. Schneider
Summary: This study compared the performance of the ACS-NSQIP SRC with other classical machine learning algorithms in predicting surgical risk, demonstrating that class imbalance in rare event prediction complicates risk assessment. Techniques to address imbalanced class sizes were found to improve classifier performance.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Education, Scientific Disciplines
Kate V. Lauer, Sarah A. Jung, Dawn M. Elfenbein
Summary: This study aims to define "teachability" and identify intraoperative behaviors that contribute to this concept. Analysis of videos from laparoscopic hernia repairs showed that residents who asked questions, proposed next steps, and initiated purposeful actions had higher teachability. The residents' actual technical skills did not appear to be significantly associated with teachability, but asking questions increased the magnitude of improvement in performance. The ability to incorporate intraoperative feedback in real time seems to be a critical aspect of teachability.
JOURNAL OF SURGICAL EDUCATION
(2023)
Editorial Material
Surgery
Meghal Shah, Tejas S. Sathe, Sukriti Bansal, Anai N. Kothari, Sophie Dream
JOURNAL OF SURGICAL RESEARCH
(2024)
Letter
Surgery
Zafer Turkyilmaz, Ramazan Karabulut, Kaan Sonmez
JOURNAL OF SURGICAL RESEARCH
(2024)
Letter
Surgery
Priyanka Jadhav, Gerald Gollin
JOURNAL OF SURGICAL RESEARCH
(2024)
Review
Surgery
Kheira Hireche, Ludovic Canaud, Pierre Antoine Peyron, Linda Sakhri, Isabelle Serres, Sanaa Kamel, Youcef Lounes, Thomas Gandet, Pierre Alric
Summary: This study evaluated the elastic properties of commonly used vascular substitutes for pulmonary artery replacement and compared their compliance and stiffness indexes to human pulmonary artery. The results showed that allogenic arterial grafts appeared to be the most suitable vascular substitutes in terms of compliance and stiffness for PA replacement.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Margaret Siu, Aixa Perez Coulter, Heather M. Grant, Reginald Alouidor, Michael Tirabassi
Summary: There is no significant difference in adverse respiratory events between intubated, critically ill patients requiring operative intervention who are kept NPO for 6 hours or longer compared to those kept NPO for less than 6 hours. Patients commonly experience periods of fasting much longer than the recommended 6-hour period by the American Society of Anesthesiologists.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Whitney Elks, Allison G. McNickle, Matthew Kelecy, Kavita Batra, Shirley Wong, Shawn Wang, Lisa Angotti, Deborah A. Kuhls, Charles St Hill, Syed F. Saquib, Paul J. Chestovich, Douglas R. Fraser
Summary: This study aimed to compare the effects of early and late enteral feeding after PEG placement on achieving nutritional therapy goals and adverse outcomes. The results showed that patients with early initiation of feeds achieved a higher percentage of goals on day 0 without an increased rate of adverse events.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Manisha B. Bhatia, Cassandra M. Anderson, Abdiwahab N. Hussein, Brian Opondo, Nereah Aruwa, Otieno Okumu, Sarah G. Fisher, Tasha Sparks Joplin, JoAnna L. Hunter-Squires, Brian W. Gray, Peter W. Saula
Summary: This study aimed to understand postoperative pediatric nutrition practices in Kenya and the United States. The results showed that in the United States, patients initiated enteral nutrition earlier and had shorter hospital stays. However, in Kenya, patients initiated enteral nutrition earlier but had no significant difference in hospital stays.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
David P. Stonko, Joseph Edwards, Hossam Abdou, Rebecca Treffalls, Patrick Walker, Jonathan J. Morrison
Summary: Raising mean arterial pressure (MAP) >90 mmHg with norepinephrine can increase gastroduodenal artery (GDA) flow and delay bowel ischemia.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
David R. Mann, Kathryn E. Engelhardt, Barry C. Gibney, Macelyn E. Batten, Eric C. Klipsch, Rupak Mukherjee, Ian C. Bostock
Summary: Pathologic upstaging is associated with decreased overall survival in cT1b esophageal cancer. Esophagectomy has better survival outcomes compared to endoscopic local tumor excision. Neoadjuvant chemoradiation therapy does not improve overall survival in cT1b lesions.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Ross Mudgway, Zachary Tran, Juan C. Quispe Espiritu, Woo Bin Bong, Hayden Schultz, Vamsi Vemireddy, Aarthy Kannappan, Marcos Michelotti, Kaushik Mukherjee, Jeffrey Quigley, Keith Scharf, Daniel Srikureja, Sharon S. Lum, Esther Wu
Summary: Comparison of medium-term outcomes between robotic-assisted cholecystectomy (RC) and laparoscopic cholecystectomy (LC) using validated quality of life (QoL) and pain assessments did not show significant differences.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Ningjie Chen, Haitao Wang, Yang Shao, Jincun Yang, Guodong Song
Summary: This study aimed to compare the therapeutic effects of activated platelet-rich plasma (PRP) prepared from elderly individuals and young adults in treating pressure ulcers (PUs). The results showed that PRP from young adults had higher platelet concentrations and greater production of growth factors, leading to better wound healing.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Brendin R. Beaulieu-Jones, Margaret T. Berrigan, Kortney A. Robinson, Jayson S. Marwaha, Tara S. Kent, Gabriel A. Brat
Summary: Introduction: Prescription opioids, including those prescribed after surgery, have greatly contributed to the US opioid epidemic. Educating opioid prescribers is a crucial component of ensuring the safe use of opioids among surgical patients. This study implemented an annual education curriculum for new surgical prescribers, resulting in significant improvements in knowledge and comfort levels. However, there remains a persistent knowledge and comfort gap among these prescribers.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Sneha G. Bhat, Madhuri Nagaraj, Courtney Balentine, Timothy Hogan, Jennie Meier, Hillary Prince, Kareem Abdelfattah, Herbert Zeh, Benjamin Levi
Summary: This pilot study examined the effects of a structured mental fitness program on academic surgeons and found significant improvement in Positive Intelligence (PQ) scores, as well as increased connectedness and shared language among participants. However, there were no significant changes in sleep, well-being, or teaching evaluations.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Kristin E. Cox, Michael A. Turner, Siamak Amirfakhri, Thinzar M. Lavin, Mojgan Hosseini, Pradipta Ghosh, Marygorret Obonyo, Takashi Murakami, Robert M. Hoffman, Paul J. Yazaki, Michael Bouvet
Summary: This study demonstrates the potential of using humanized anti-carcinoembryonic antigen (CEA) antibodies conjugated with near-infrared dyes to specifically label gastric cancers in mouse models. Orthotopic models showed bright and specific labeling with more than ten times higher tumor-to-background ratios compared to the control. This tumor-specific fluorescent antibody has promising potential as a clinical tool for improving visualization of gastric cancer margins during surgical resection.
JOURNAL OF SURGICAL RESEARCH
(2024)
Review
Surgery
Sarah Maki, Melissa Leon, Emily Glenn, Tiffany Tanner, Crystal Krause
Summary: This scoping review analyzed the literature on the use of broadband personality tests in the bariatric surgical population to optimize weight loss outcomes. The study found significant associations between personality scales and weight loss, but inconsistent reporting of outcome measures made it challenging to draw concrete conclusions. The American Society for Metabolic and Bariatric Surgery recommends standardization of outcome reporting to improve the reliability of predicting weight loss outcomes.
JOURNAL OF SURGICAL RESEARCH
(2024)