The preTCR-dependent DN3 to DP transition requires Notch signaling, is improved by CXCL12 signaling and is inhibited by IL-7 signaling

Fate Mapping Reveals Separate Origins of T Cells and Myeloid Lineages in the Thymus

(2010) Susan M. Schlenner et al.   IMMUNITY

Postselection Thymocyte Maturation and Emigration Are Independent of IL-7 and ERK5

(2010) M. A. Weinreich et al.   JOURNAL OF IMMUNOLOGY

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

(2010) Siew Siew Pang et al.   NATURE

An Essential Developmental Checkpoint for Production of the T Cell Lineage

(2010) T. Ikawa et al.   SCIENCE

Early T cell development and the pitfalls of potential

(2010) Susan M. Schlenner et al.   TRENDS IN IMMUNOLOGY

Stromal cell-derived factor 1α and CXCR4: newly defined requirements for efficient thymic β-selection

(2010) Michelle L. Janas et al.   TRENDS IN IMMUNOLOGY

Thymic development beyond β-selection requires phosphatidylinositol 3-kinase activation by CXCR4

(2009) Michelle L. Janas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis

(2008) T. Serwold et al.   BLOOD

TCR-β chains derived from peripheral γδ T cells can take part in αβ T-cell development

(2008) Nabil Bosco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Delta-like 4 is indispensable in thymic environment specific for T cell development

(2008) Katsuto Hozumi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment

(2008) Ute Koch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adult T-cell progenitors retain myeloid potential

(2008) Haruka Wada et al.   NATURE

The earliest thymic progenitors for T cells possess myeloid lineage potential

(2008) J. Jeremiah Bell et al.   NATURE