IL-27 increases the proliferation and effector functions of human naïve CD8+ T lymphocytes and promotes their development into Tc1 cells

STAT3 Is Indispensable to IL-27-Mediated Cell Proliferation but Not to IL-27-Induced Th1 Differentiation and Suppression of Proinflammatory Cytokine Production

(2014) T. Owaki et al.   JOURNAL OF IMMUNOLOGY

IL-27 Activates Human Monocytes via STAT1 and Suppresses IL-10 Production but the Inflammatory Functions of IL-27 Are Abrogated by TLRs and p38

(2014) George D. Kalliolias et al.   JOURNAL OF IMMUNOLOGY

Interleukin-27 Induces a STAT1/3- and NF-κB-dependent Proinflammatory Cytokine Profile in Human Monocytes

(2010) Christina Guzzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shaping Successful and Unsuccessful CD8 T Cell Responses Following Infection

(2010) Maureen A. Cox et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

A Pivotal Role for Interleukin-27 in CD8+T Cell Functions and Generation of Cytotoxic T Lymphocytes

(2010) Noriko Morishima et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Quick to remember, slow to forget: rapid recall responses of memory CD8+ T cells

(2009) Joanna R DiSpirito et al.   CELL RESEARCH

Heterogeneity and plasticity of T helper cells

(2009) Jinfang Zhu et al.   CELL RESEARCH

A partial form of recessive STAT1 deficiency in humans

(2009) Ariane Chapgier et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-27 Is a Key Regulator of IL-10 and IL-17 Production by Human CD4+ T Cells

(2009) G. Murugaiyan et al.   JOURNAL OF IMMUNOLOGY

IL-27 Abrogates Receptor Activator of NF- B Ligand-Mediated Osteoclastogenesis of Human Granulocyte-Macrophage Colony-Forming Unit Cells through STAT1-Dependent Inhibition of c-Fos

(2009) M. Furukawa et al.   JOURNAL OF IMMUNOLOGY

IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells

(2009) C. Diveu et al.   JOURNAL OF IMMUNOLOGY

Interleukin 27: a double-edged sword for offense and defense

(2009) Hiroki Yoshida et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human Naturally Occurring and Adaptive Regulatory T cells Secrete High Levels of Leukaemia Inhibitory Factor upon Activation

(2008) M. Mahic et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY