4.5 Article

Mouse Th17 cells: Current understanding of their generation and regulation

Journal

EUROPEAN JOURNAL OF IMMUNOLOGY
Volume 39, Issue 3, Pages 640-644

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/eji.200839076

Keywords

IL-17; Inflammation; Th17 cells

Categories

Funding

  1. NIH
  2. MD Anderson Cancer Center
  3. Cancer Research Institute
  4. American Lung Association and Lymphoma and Leukemia Society

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IL-17-expressing CD4(+) T cells have been recently recognized as a new subset of Th cells, namely Th17 cells. Considerable progress has been made in understanding the developmental regulation of mouse Th17 cells. Here, I summarize this knowledge and discuss on the relationship of Th17 with regulatory and follicular helper (Th17) cells.

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