Journal
EUROPEAN JOURNAL OF IMMUNOLOGY
Volume 39, Issue 3, Pages 655-657Publisher
WILEY
DOI: 10.1002/eji.200839198
Keywords
Diet; Environment; Microbes; Th17; Toxins
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Funding
- NINDS NIH HHS [P01 NS038037] Funding Source: Medline
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Th17 cells participate in the control of extracellular bacteria and fungi, but dysregulated Th17 cell activity can result in immunopathology. Thus, the generation and the activity of Th17 cells should be tightly regulated, and simultaneously it should be able to respond to the challenges presented by a changing environment. in this viewpoint, we discuss some of the mechanisms by which microbes, dietary components and environmental toxins influence the Th17 response.
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