Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer

Biallelic MUTYH mutations can mimic Lynch syndrome

(2014) Monika Morak et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis

(2014) Laura Valle et al.   HUMAN MOLECULAR GENETICS

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes

(2013) Tae-Min Kim et al.   CELL

Somatic Mutations in MLH1 and MSH2 Are a Frequent Cause of Mismatch-Repair Deficiency in Lynch Syndrome-Like Tumors

(2013) Arjen R. Mensenkamp et al.   GASTROENTEROLOGY

Colorectal cancer risk variants on 11q23 and 15q13 are associated with unexplained adenomatous polyposis

(2013) Frederik J Hes et al.   JOURNAL OF MEDICAL GENETICS

The burden of faulty proofreading in colon cancer

(2013) Somasekar Seshagiri   NATURE GENETICS

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

(2012) Claire Palles et al.   NATURE GENETICS

Rapid KRAS, EGFR, BRAF and PIK3CA Mutation Analysis of Fine Needle Aspirates from Non-Small-Cell Lung Cancer Using Allele-Specific qPCR

(2011) Ronald van Eijk et al.   PLoS One

Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer

(2010) Rintaro Yoshida et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions

(2010) Jérémie H. Lefevre et al.   Familial Cancer

DNA replication fidelity and cancer

(2010) Bradley D. Preston et al.   SEMINARS IN CANCER BIOLOGY

Enrichment of Low Penetrance Susceptibility Loci in a Dutch Familial Colorectal Cancer Cohort

(2009) A. Middeldorp et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases

(2008) Scott D McCulloch et al.   CELL RESEARCH

Germline MutY Human Homologue Mutations and Colorectal Cancer: A Multisite Case-Control Study

(2008) Sean P. Cleary et al.   GASTROENTEROLOGY