Low-density lipoprotein receptor mutations generate synthetic genome-wide associations

Estimating Causal Effects of Genetic Risk Variants for Breast Cancer Using Marker Data from Bilateral and Familial Cases

(2012) F. Dudbridge et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The Rotterdam Study: 2012 objectives and design update

(2011) Albert Hofman et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Rare variants, common markers: synthetic association and beyond

(2011) Jack W. Kent   GENETIC EPIDEMIOLOGY

The Importance of Synthetic Associations Will Only Be Resolved Empirically

(2011) David B. Goldstein   PLOS BIOLOGY

Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results

(2011) Naomi R. Wray et al.   PLOS BIOLOGY

Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals

(2011) Carl A. Anderson et al.   PLOS BIOLOGY

Interpretation of Association Signals and Identification of Causal Variants from Genome-wide Association Studies

(2010) Kai Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

(2010) Christopher T Johansen et al.   NATURE GENETICS

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

Update and Analysis of the University College London Low Density Lipoprotein Receptor Familial Hypercholesterolemia Database

(2008) S. E. A. Leigh et al.   ANNALS OF HUMAN GENETICS

Genome-wide association studies: potential next steps on a genetic journey

(2008) M. I. McCarthy et al.   HUMAN MOLECULAR GENETICS

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

(2008) Mark I. McCarthy et al.   NATURE REVIEWS GENETICS