Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction

Cancer Therapy–Induced Cardiac Toxicity in Early Breast Cancer

(2012) Michel G. Khouri et al.   CIRCULATION

Cancer drugs and the heart: importance and management

(2012) T. M. Suter et al.   EUROPEAN HEART JOURNAL

Detection, monitoring, and management of trastuzumab-induced left ventricular dysfunction: an actual challenge

(2012) Carlo G. Tocchetti et al.   EUROPEAN JOURNAL OF HEART FAILURE

Oxidative and nitrosative stress in the maintenance of myocardial function

(2012) Yixuan Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

(2012) Sui Zhang et al.   NATURE MEDICINE

Comparison of preclinical cardiotoxic effects of different ErbB2 inhibitors

(2011) Carmine Fedele et al.   BREAST CANCER RESEARCH AND TREATMENT

Role of ranolazine in angina, heart failure, arrhythmias, and diabetes

(2011) Samuel Sossalla et al.   PHARMACOLOGY & THERAPEUTICS

Nox2 NADPH Oxidase Promotes Pathologic Cardiac Remodeling Associated with Doxorubicin Chemotherapy

(2010) Y. Zhao et al.   CANCER RESEARCH

Elevated Cytosolic Na + Increases Mitochondrial Formation of Reactive Oxygen Species in Failing Cardiac Myocytes

(2010) Michael Kohlhaas et al.   CIRCULATION

Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology

(2010) Thomas Eschenhagen et al.   EUROPEAN JOURNAL OF HEART FAILURE

Na+/K+-ATPase inhibition by ouabain induces CaMKII-dependent apoptosis in adult rat cardiac myocytes

(2010) Luciana Sapia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

B-Type Natriuretic Peptide and the Effect of Ranolazine in Patients With Non–ST-Segment Elevation Acute Coronary Syndromes

(2010) David A. Morrow et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro

(2009) Partha Mukhopadhyay et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66Shc and monoamine oxidase

(2009) Fabio Di Lisa et al.   BASIC RESEARCH IN CARDIOLOGY

Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix

(2009) A. D. Kandasamy et al.   CARDIOVASCULAR RESEARCH

Ranolazine as a Cardioplegia Additive Improves Recovery of Diastolic Function in Isolated Rat Hearts

(2009) H. Hwang et al.   CIRCULATION

Regulation of Intracellular and Mitochondrial Sodium in Health and Disease

(2009) Elizabeth Murphy et al.   CIRCULATION RESEARCH

The Late Na+ Current (INa) Inhibitor Ranolazine Attenuates Effects of Palmitoyl-L-Carnitine to Increase Late INa and Cause Ventricular Diastolic Dysfunction

(2009) Y. Wu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure

(2008) Sharad Rastogi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation

(2008) Jeffrey R. Erickson et al.   CELL

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL