Article
Cardiac & Cardiovascular Systems
Patricia F. Trevizan, Ligia M. Antunes-Correa, Denise M. L. Lobo, Patricia A. Oliveira, Dirceu R. de Almeida, Maria Cristina D. Abduch, Wilson Mathias Junior, Ludhmila Abrahao Hajjar, Roberto Kalil Filho, Carlos Eduardo Negrao
Summary: The study found that combined inspiratory muscle training and aerobic exercise training did not have more pronounced effects on neurovascular control in patients with heart failure with reduced ejection fraction compared to aerobic exercise training alone.
Article
Cardiac & Cardiovascular Systems
Ioannis D. Laoutaris, Ewa Piotrowicz, Manolis S. Kallistratos, Athanasios Dritsas, Niki Dimaki, Dimitris Miliopoulos, Maria Andriopoulou, Athanasios J. Manolis, Maurizio Volterrani, Massimo F. Piepoli, Andrew J. S. Coats, Stamatis Adamopoulos
Summary: The ARISTOS-HF trial showed that exercise training for 180 min/week, particularly the ARIS training regime, is recommended for heart failure patients.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2021)
Article
Multidisciplinary Sciences
Horesh Dor-Haim, Michal Horowitz, Eldad Yaakobi, Sara Katzburg, Sharon Barak
Summary: The study aimed to compare the effectiveness of moderate-intensity continuous-aerobic training (CAT) versus SCT on cardiac electrical measures in patients post-MI with reduced left ventricular function, as well as their effect on anthropometric measures.
Article
Medicine, Research & Experimental
Giuseppe Potrick Stefani, Lucas Capalonga, Lucas Ribeiro da Silva, Thiago Gomes Heck, Matias Nunes Frizzo, Lucas Machado Sulzbacher, Maicon Machado Sulzbacher, Diovana de Batista, Samlai Vedovatto, Ana Paula Santin Bertoni, Marcia Rosangela Wink, Pedro Dal Lago
Summary: The study found that combined exercise training (CET) with 13-alanine and L-histidine supplementation in rats with heart failure (HF) can improve functional capacity and biochemical variables, reduce oxidative stress and inflammation, and affect mRNA expression of calcium transporters in the skeletal muscle.
Article
Biochemistry & Molecular Biology
Vitor Loureiro da Silva, Gustavo Augusto Ferreira Mota, Sergio Luiz Borges de Souza, Dijon Henrique Salome de Campos, Alexandre Barroso Melo, Danielle Fernandes Vileigas, Priscila Murucci Coelho, Paula Grippa Sant'Ana, Carlos Padovani, Ana Paula Lima-Leopoldo, Silmeia Garcia Zanati Bazan, Andre Soares Leopoldo, Antonio Carlos Cicogna
Summary: Aerobic exercise training (AET) can improve heart disease by restoring calcium (Ca2+) handling, optimizing intracellular Ca2+ flow, and attenuating cardiac functional impairment. However, the effects of AET on Ca2+ transit and cardiac function in rats with heart failure caused by aortic stenosis (AoS) remain unclear. This study evaluated the impact of AET on Ca2+ handling and cardiac function in rats with AoS-induced heart failure.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Cardiac & Cardiovascular Systems
Ray W. Squires, Amanda R. Bonikowske
Summary: Heart transplantation is the preferred treatment for end-stage chronic heart failure. Although many patients experience improved functional ability after transplantation, they still face the challenges of acute rejection and other comorbidities. Exercise training, recommended before and after transplantation, can improve exercise capacity and skeletal muscle strength without altering immunosuppression.
PROGRESS IN CARDIOVASCULAR DISEASES
(2022)
Article
Cardiac & Cardiovascular Systems
Peter H. Brubaker, Barbara J. Nicklas, Denise K. Houston, W. Gregory Hundley, Haiying Chen, Anthony J. A. Molina, W. Mary Lyles, Benjamin Nelson, Bharathi Upadhya, Russell Newland, Dalane W. Kitzman
Summary: This study aimed to investigate whether adding resistance training (RT) to combined caloric restriction (CR) and aerobic exercise training (AT) can reduce skeletal muscle loss and further improve outcomes in older obese heart failure patients. The results showed that adding RT to CR+AT increased leg muscle strength and quality, but did not reduce skeletal muscle and weight loss, or further increase VO2peak or quality-of-life.
CIRCULATION-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Nihan Katayifci, Meral Bosnak Guclu, Fatih Sen
Summary: This study compared the effects of inspiratory muscle strength and endurance training on exercise capacity, quality of life, and pulmonary function in pacemaker patients with heart failure. The results showed that both types of training had similar improvements in these outcomes.
Article
Rehabilitation
Jui-Fang Liu, Nai-Ying Kuo, Teng-Pei Fang, Jui-O Chen, Hung- Lu, Hui-Ling Lin
Summary: The study concluded that a six-week period of inspiratory muscle training and aerobic exercise significantly improved respiratory muscle strength and aerobic exercise performance in lung cancer patients after VATS, as early as 2 weeks postoperatively.
CLINICAL REHABILITATION
(2021)
Article
Cardiac & Cardiovascular Systems
Derek Tran, Phillip Munoz, Edmund M. T. Lau, Jennifer A. Alison, Martin Brown, Yizhong Zheng, Patricia Corkery, Keith Wong, Steven Lindstrom, David S. Celermajer, Glen M. Davis, Rachael Cordina
Summary: Exercise intolerance is common in early stages of PAH and is associated with poorer prognosis. This study found that IMT can improve inspiratory muscle strength and 6-minute walk distance in PAH patients after 8 weeks.
HEART LUNG AND CIRCULATION
(2021)
Article
Cardiac & Cardiovascular Systems
Marine Kirsch, Moatemri Feriel, Lamar Tanguy Aurelia, Kovalska Oksana, Blanchard Jean Christophe, Ledru Francois, Cristofini Pascal, Damien Vitiello, Iliou Marie-Christine
Summary: This study aimed to evaluate the impact of a 4-week cardiac rehabilitation program on cardiopulmonary exercise testing and echocardiography parameters in chronic heart failure patients. The results showed that the training program significantly improved peak oxygen consumption, left ventricular outflow tract velocity time integral, circulatory power, and ventilatory power, while decreasing the VE/VCO2 slope. Responders to training had higher left ventricle contractile reserve compared to non-responders.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Hui Li, Lingling Tao, Yuewi Huang, Ziyang Li, Jianrong Zhao
Summary: This study found that inspiratory muscle training has a significant positive effect on peak oxygen consumption, maximum inspiratory pressure, ventilation efficiency, and quality of life in patients with heart failure. However, it has no significant effect on six-minute walking distance and lung function. Additionally, inspiratory muscle training has a more significant impact on peak oxygen consumption and quality of life in patients with heart failure with preserved ejection fraction.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Maurizio Volterrani, Giuseppe Caminiti, Marco Alfonso Perrone, Anna Cerrito, Alessio Franchini, Vincenzo Manzi, Ferdinando Iellamo
Summary: The effectiveness of concurrent exercise training program in patients with chronic heart failure was evaluated. The study showed that concurrent training resulted in significant improvements in functional capacity and muscular strength, compared to single-mode aerobic training, without major side effects.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cell Biology
Andrea Tryfonos, Giorgos Tzanis, Theodore Pitsolis, Eleftherios Karatzanos, Michael Koutsilieris, Serafim Nanas, Anastassios Philippou
Summary: This study demonstrates that both high-intensity interval training (HIIT) and combined HIIT with strength training similarly enhance the expression profile of angiogenic factors in skeletal muscle of heart failure (HF) patients. This may drive the angiogenic program in the trained muscles, although the gene expression increases were only partially related to muscle capillarization.
Article
Cardiac & Cardiovascular Systems
Vandana Sachdev, Kavita Sharma, Steven J. Keteyian, Charina F. Alcain, Patrice Desvigne-Nickens, Jerome L. Fleg, Viorel G. Florea, Barry A. Franklin, Maya Guglin, Martin Halle, Eric S. Leifer, Gurusher Panjrath, Emily A. Tinsley, Renee P. Wong, Dalane W. Kitzman
Summary: HFpEF is a common form of heart failure with increasing prevalence and worsening outcomes. Pharmacological interventions have shown limited efficacy, while exercise-based interventions consistently improve symptoms and quality of life. This may be attributed to the pleiotropic effects of exercise, which positively influence the various abnormalities contributing to exercise intolerance in HFpEF. This article critically examines the effects of exercise-based therapies, compares them with other cardiovascular conditions, and highlights gaps in implementation for future research.
Article
Rehabilitation
Nastasia Marinus, Dominique Hansen, Peter Feys, Raf Meesen, Annick Timmermans, Joke Spildooren
Summary: This study analyzed the impact of television images on the motivation and exercise intensity of older adults in residential care during cycling exercises. The results indicated that the addition of television images may increase the exercise intensity and motivation of older adults.
DISABILITY AND REHABILITATION-ASSISTIVE TECHNOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Martijn Scherrenberg, Nastasia Marinus, Francesco Giallauria, Maarten Falter, Hareld Kemps, Matthias Wilhelm, Eva Prescott, Carlo Vigorito, Ed De Kluiver, Gerson Cipriano Jr, Paul Dendale, Dominique Hansen
Summary: Due to advancements in cardiovascular medicine, patients with significant disease burden now have a better prognosis. However, aging-related syndromes like frailty become more common among these patients. Frailty leads to exercise intolerance and compromised adherence to cardiovascular rehabilitation. Recent technological advancements in telemedicine have made it possible to remotely monitor and supervise cardiovascular patients, providing promising benefits. This article aims to provide a framework for developing and implementing a tele-rehabilitation program for managing prevention and rehabilitation in cardiovascular disease patients with frailty.
TRENDS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Tin Gojevic, Lisa Van Ryckeghem, Siddharth Jogani, Ines Frederix, Elise Bakelants, Thibault Petit, Sarah Stroobants, Paul Dendale, Virginie Bito, Lieven Herbots, Dominique Hansen, Jan Verwerft
Summary: In patients with Type 2 diabetes mellitus, the dyspnoeic group showed abnormal cardiac and pulmonary vascular function during exercise, including lower LV systolic reserve and higher mean pulmonary arterial pressures. These abnormalities may contribute to exertional dyspnoea and reduced exercise capacity in these patients.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Roberto F. E. Pedretti, Dominique Hansen, Marco Ambrosetti, Maria Back, Thomas Berger, Mariana Cordeiro Ferreira, Veronique Cornelissen, Constantinos H. Davos, Wolfram Doehner, Carmen de Pablo Y. Zarzosa, Ines Frederix, Andrea Greco, Donata Kurpas, Matthias Michal, Elena Osto, Susanne Pedersen, Rita Esmeralda Salvador, Maria Simonenko, Patrizia Steca, David R. Thompson, Matthias Wilhelm, Ana Abreu
Summary: Optimal patient adherence to treatment is crucial for successful secondary prevention of cardiovascular disease (CVD). However, unsatisfactory adherence rates have been consistently observed for CVD risk factors and treatment. This consensus document provides a modern reappraisal of adherence to optimal treatment and offers simple, practical, and feasible suggestions to achieve this goal in the clinical setting, focusing on evidence-based concepts.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Anesthesiology
Gustavo dos Santos Ribeiro, Thomas Beltrame, Luis Fernando Deresz, Dominique Hansen, Piergiuseppe Agostoni, Marlus Karsten
Summary: This study presents a software development for the standardized diagnosis of exercise oscillatory ventilation (EOV) in heart failure patients. The software demonstrates high reliability in both inter- and intra-rater agreements.
JOURNAL OF CLINICAL MONITORING AND COMPUTING
(2023)
Review
Neurosciences
Nastasia Marinus, Sybren Van Hoornweder, Marthe Aarts, Jessie Vanbilsen, Dominique Hansen, Raf Meesen
Summary: This article examines the effect of transcranial direct current stimulation (tDCS) on the three core components of physical fitness: muscle strength, endurance, and cardiopulmonary endurance. The study found that tDCS is most effective in improving muscle endurance, with approximately 69% of the studies reporting positive effects. The primary motor cortex and dorsolateral prefrontal cortex were the most targeted areas, showing positive results on muscle and cardiopulmonary endurance.
EXPERIMENTAL BRAIN RESEARCH
(2023)
Review
Rehabilitation
Elogni R. Amanzonwe, Lisa Tedesco Triccas, Leopold Codjo, Dominique Hansen, Peter Feys, Oyene Kossi
Summary: This study analyzed the optimal dosage and effectiveness of aerobic training (AT) and resistance training (RT) on balance, walking capacity, and quality of life (QoL) in stroke survivors. The results showed that AT was the most effective in improving walking capacity, while combining AT and RT was beneficial for improving QoL. High-dose aerobic exercise conducted in rehabilitation facilities was more effective in improving walking capacity in chronic stroke patients.
SOUTH AFRICAN JOURNAL OF PHYSIOTHERAPY
(2023)
Article
Cardiac & Cardiovascular Systems
Ruben De Bosscher, Christophe Dausin, Piet Claus, Jan Bogaert, Steven Dymarkowski, Kaatje Goetschalckx, Olivier Ghekiere, Caroline M. van de Heyning, Paul Van Herck, Bernard Paelinck, Haroun El Addouli, Andre La Gerche, Lieven Herbots, Rik Willems, Hein Heidbuchel, Guido Claessen, Mathias Claeys, Peter Hespel, Tom Dresselaers, Hielko Miljoen, Ann Belmans, Kasper Favere, Dorien Vermeulen, Isabel Witvrouwen, Dominique Hansen, Bert Op't Eijnde, Daisy Thijs, Peter Vanvoorden, Sofie Van Soest
Summary: The impact of long-term endurance sport participation on coronary atherosclerosis and acute cardiac events remains controversial. A study found that lifelong endurance athletes had a higher prevalence of coronary plaques compared to healthy individuals. Further research is needed to understand the risk of cardiovascular events in high-intensity endurance exercise.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Elena Marques-Sule, Dominique Hansen, Luis Almenar, Pallav Deka, Trinidad Sentandreu-Mano, Raquel Lopez-Vilella, Leonie Klompstra, Felipe V. C. Machado
Summary: This study aimed to explore the central factors and interconnections among different types of motivation to exercise, physical activity, sedentary time, psychosomatic characteristics, diet, and activity limitations in post-heart transplant patients. The results showed that functional capacity and autonomous motivation to exercise are the most important targets for improving physical activity levels and sedentary time in these patients. Additionally, frailty and sarcopenia risk were found to mediate the effects of other factors on physical activity and sedentary time.
EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING
(2023)
Article
Cardiac & Cardiovascular Systems
Juliana Goulart Prata Oliveira Milani, Mauricio Milani, Graziella Franca Bernardelli Cipriano, Isac de Castro, Dominique Hansen, Gerson Cipriano Junior
Summary: The purpose of this study is to provide comprehensive reference values for oxygen uptake efficiency slope (OUES) in healthy adults and explore international heterogeneity through published databases. A cross-sectional study was conducted with treadmill cardiopulmonary exercise testing (CPX) on a Brazilian healthy adult sample, and prediction equations were calculated. International data were pooled and differences were explored. Reference value tables and predictive equations were provided for OUES in both sexes. The study found substantial heterogeneity among Brazilian, European, and Japanese data, and the differences were reduced in the BSA-normalized OUES.
JOURNAL OF CARDIOPULMONARY REHABILITATION AND PREVENTION
(2023)
Article
Health Care Sciences & Services
Toshiki Kaihara, Dominique Hansen, Supraja Sankaran, Martijn Scherrenberg, Maarten Falter, Linqi Xu, Karin Coninx, Paul Dendale
Summary: The American College of Sports Medicine determined the energy consumption of daily activities and sports. Cardiac telerehabilitation (CTR) requires knowing the energy consumption of people in daily life outside of cardiac rehabilitation activities. Two studies were conducted to investigate if the estimated values are valid in CTR. The findings suggest that the estimated values of energy expenditure in CTR do not accurately reflect the actual exercise done by patients, which can impact the quantification of exercise dose in rehabilitation programs.
JOURNAL OF TELEMEDICINE AND TELECARE
(2023)
Article
Education & Educational Research
Dominique Hansen, Nastasia Marinus, Veronique Cornelissen, Wim Ramakers, Karin Coninx
Summary: Exercise prescriptions for cardiovascular disease patients by physiotherapists show better agreement with European recommendations when using the EXPERT Training tool. The tool leads to increased exercise frequency, program duration, and total exercise volume. The study highlights the educational potential of the tool.
MEDICAL EDUCATION ONLINE
(2023)
Article
Physiology
Thibaux Van der Stede, Jan Spaas, Sarah de Jager, Jana De Brandt, Camilla Hansen, Jan Stautemas, Bjarne Vercammen, Siegrid De Baere, Siska Croubels, Charles-Henri Van Assche, Berta Cillero Pastor, Michiel Vandenbosch, Ruud Van Thienen, Kenneth Verboven, Dominique Hansen, Thierry Bove, Bruno Lapauw, Charles Van Praet, Karel Decaestecker, Bart Vanaudenaerde, Bert O. Eijnde, Lasse Gliemann, Ylva Hellsten, Wim Derave
Summary: This study systematically analyzed the distribution and metabolism of histidine-containing dipeptides (HCDs) in mouse, rat, and human tissues using a sensitive UHPLC-MS/MS approach. The results show that tissue HCD levels are uniquely produced by carnosine synthase (CARNS1) in fast-twitch skeletal muscle fibers and brain oligodendrocytes. Additionally, N-acetylcarnosine is a stable plasma HCD and is enriched in human skeletal muscles.
Article
Cardiac & Cardiovascular Systems
Nastasia Marinus, Veronique Cornelissen, Raf Meesen, Karin Coninx, Dominique Hansen
Summary: This study examines whether exercise prescriptions by physiotherapists to patients with cardiovascular disease are in line with European recommendations. The results show a wide variability in exercise prescriptions among physiotherapists, with many prescriptions not aligning with the recommendations.
EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING
(2023)
Article
Cardiac & Cardiovascular Systems
Christian Verdicchio, Nicole Freene, Matthew Hollings, Andrew Maiorana, Tom Briffa, Robyn Gallagher, Jeroen M. Hendriks, Bridget Abell, Alex Brown, David Colquhoun, Erin Howden, Dominique Hansen, Stacey Reading, Julie Redfern
Summary: This article provides practical guidance on the assessment and prescription of exercise and physical activity in cardiac rehabilitation, with a patient-centered approach and consideration of the latest international guidelines, scientific evidence, and technology methods.
HEART LUNG AND CIRCULATION
(2023)