Clinical trials in acute heart failure: simpler solutions to complex problems. Consensus document arising from a European Society of Cardiology cardiovascular round-table think tank on acute heart failure, 12 May 2009

Effect of Nesiritide in Patients with Acute Decompensated Heart Failure

(2011) C.M. O'Connor et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Trials of Pharmacological Therapies in Acute Heart Failure Syndromes

(2010) G. Michael Felker et al.   Circulation-Heart Failure

EURObservationalResearch Programme: The Heart Failure Pilot Survey (ESC-HF Pilot)

(2010) Aldo P. Maggioni et al.   EUROPEAN JOURNAL OF HEART FAILURE

Assessing and grading congestion in acute heart failure: a scientific statement from the Acute Heart Failure Committee of the Heart Failure Association of the European Society of Cardiology and endorsed by the European Society of Intensive Care Medicine

(2010) Mihai Gheorghiade et al.   EUROPEAN JOURNAL OF HEART FAILURE

Rationale and design of the multicentre, randomized, double-blind, placebo-controlled Aliskiren Trial on Acute Heart Failure Outcomes (ASTRONAUT)

(2010) Mihai Gheorghiade et al.   EUROPEAN JOURNAL OF HEART FAILURE

Cinaciguat (BAY 58–2667) Improves Cardiopulmonary Hemodynamics in Patients With Acute Decompensated Heart Failure

(2009) Harald Lapp et al.   CIRCULATION

Clinical trials update from the American College of Cardiology 2009: ADMIRE-HF, PRIMA, STICH, REVERSE, IRIS, partial ventricular support, FIX-HF-5, vagal stimulation, REVIVAL-3, pre-RELAX-AHF, ACTIVE-A, HF-ACTION, JUPITER, AURORA, and OMEGA

(2009) John G.F. Cleland et al.   EUROPEAN JOURNAL OF HEART FAILURE

Pharmacodynamics Pharmacodynamics of a Novel Designer Natriuretic Peptide, CD-NP, in a First-in-Human Clinical Trial in Healthy Subjects

(2009) Candace Y. W. Lee et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Micronutrient Deficiencies

(2009) Victor Soukoulis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Proof of Concept

(2009) Bart Meyns et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Serum Neutrophil Gelatinase-Associated Lipocalin as a Marker of Renal Function in Patients with Chronic Heart Failure and Coronary Artery Disease

(2009) Boguslaw Poniatowski et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study

(2009) John R Teerlink et al.   LANCET

Standardizing care for acute decompensated heart failure in a large megatrial: The approach for the Acute Studies of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure (ASCEND-HF)

(2008) Justin A. Ezekowitz et al.   AMERICAN HEART JOURNAL

Factors Identified as Precipitating Hospital Admissions for Heart Failure and Clinical OutcomesFindings From OPTIMIZE-HF

(2008) Gregg C. Fonarow   ARCHIVES OF INTERNAL MEDICINE

The powerful cardioprotective effects of urocortin and the corticotropin releasing hormone (CRH) family

(2008) Sean M. Davidson et al.   BIOCHEMICAL PHARMACOLOGY

A proposal to standardize dyspnoea measurement in clinical trials of acute heart failure syndromes: the need for a uniform approach

(2008) P. S. Pang et al.   EUROPEAN HEART JOURNAL

ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008‡

(2008) Kenneth Dickstein et al.   EUROPEAN JOURNAL OF HEART FAILURE

Timing of Immunoreactive B-Type Natriuretic Peptide Levels and Treatment Delay in Acute Decompensated Heart Failure

(2008) Alan S. Maisel et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Design, Synthesis, and Actions of a Novel Chimeric Natriuretic Peptide: CD-NP

(2008) Ondrej Lisy et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Hemodynamic, Echocardiographic, and Neurohormonal Effects of Istaroxime, a Novel Intravenous Inotropic and Lusitropic Agent

(2008) Mihai Gheorghiade et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial

(2008) GISSI-HF investigators   LANCET

Epidemiology and risk stratification in acute heart failure

(2007) Gregg C. Fonarow   AMERICAN HEART JOURNAL

Usefulness of B-Type Natriuretic Peptide and Cardiac Troponin Levels to Predict In-Hospital Mortality from ADHERE

(2007) Gregg C. Fonarow et al.   AMERICAN JOURNAL OF CARDIOLOGY