Article
Pediatrics
Timothy Edwards, Emir Tas, Kenneth Leclerc, Elisabet Borsheim
Summary: Noninvasive cardiopulmonary exercise testing (CPET) is useful for analyzing pulmonary gas exchange and cardiovascular responses. This case report demonstrates how CPET can be used to identify potential cardiac pathologies in at-risk adolescents. An asymptomatic adolescent with abnormal CPET response and a family history of early-age CAD had elevated circulating hs-CRP levels, further supporting the significance of the abnormal CPET response. These findings highlight the importance of thorough clinical evaluation and monitoring in at-risk adolescents, especially when CPET abnormalities are combined with elevated hs-CRP.
FRONTIERS IN PEDIATRICS
(2023)
Review
Physiology
Maria F. Ionescu, Sethu Mani-Babu, Luiza H. Degani-Costa, Martin Johnson, Chelliah Paramasivan, Karl Sylvester, Jonathan Fuld
Summary: Dysfunctional breathing (DB) is a condition that affects individuals in various situations, including athletes, and can be diagnosed and managed using cardiopulmonary exercise testing (CPET). Proper recognition of DB is important for treatment and can lead to significant benefits for individuals.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Respiratory System
Robert A. Lewis, Catherine G. Billings, Judith A. Hurdman, Ian A. Smith, Matthew Austin, Iain J. Armstrong, Jennifer Middleton, Alexander M. K. Rothman, John Harrington, Neil Hamilton, Abdul G. Hameed, A. A. Roger Thompson, Athanasios Charalampopoulos, Charlie A. Elliot, Allan Lawrie, Ian Sabroe, Jim M. Wild, Andrew J. Swift, Robin Condliffe, David G. Kiely
Summary: This study found that the incremental shuttle walking test can help stratify mortality risk in PAH patients at baseline and follow-up. Additionally, the test has been incorporated into risk assessment methods and accurately identifies different levels of risk.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2021)
Article
Respiratory System
Hanqing Zhu, Xingxing Sun, Yuan Cao, Bigyan Pudasaini, Wenlan Yang, Jinming Liu, Jian Guo
Summary: This study evaluated and monitored chronic thromboembolic pulmonary hypertension (CTEPH) noninvasively and effectively by CPET and PFT methods. Parameters such as minute ventilation at anaerobic threshold and oxygen uptake at peak were found to be independent predictors for severe CTEPH, with moderate efficacy in identifying the condition. The combination of these parameters had a moderate utility value in identifying severe CTEPH as well.
BMC PULMONARY MEDICINE
(2021)
Article
Pediatrics
Adam W. Powell, Wayne A. Mays, Samuel G. Wittekind, Clifford Chin, Sandra K. Knecht, Sean M. Lang, Alexander R. Opotowsky
Summary: This study investigated the impact of sport and school restrictions during the early stages of the COVID-19 pandemic on exercise performance and body composition in children and young adults with heart disease. The results showed that the pandemic and related lifestyle changes did not have substantial negative effects on aerobic fitness or body composition in this population.
FRONTIERS IN PEDIATRICS
(2023)
Review
Rehabilitation
Eva Pella, Marieta P. Theodorakopoulou, Afroditi K. Boutou, Maria-Eleni Alexandrou, Dimitra-Rafailia Bakaloudi, Despoina Sarridou, Aristi Boulmpou, Christodoulos Papadopoulos, Aikaterini Papagianni, Pantelis Sarafidis
Summary: This systematic review and meta-analysis compares individuals with chronic kidney disease (CKD) to those without CKD using cardiopulmonary exercise testing (CPET). The study found that CKD patients have lower cardiopulmonary reserve compared to controls and perform better than controls with heart failure without CKD. The findings suggest the need for widespread application of rehabilitation programs for individuals with CKD.
ANNALS OF PHYSICAL AND REHABILITATION MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Reid Ponder, Luke Chez, Carl J. Rosenthal, Katia Bravo, Gentian Lluri, Leigh Reardon, Jeannette Lin, Daniel S. Levi, Jamil A. Aboulhosn
Summary: This study found that Fontan patients have variable exercise capacity. Factors such as BMI, Fontan pressure, and cardiac outputs are associated with high tolerance. High-performing patients also have higher activity levels, serum albumin levels, oxygen saturations, and less severe liver fibrosis. Predictive factors for high tolerance include Fontan pressure, oxygen saturation, albumin level, activity level, age at Fontan surgery, NYHA heart failure class, and BMI.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Physiology
Hayley Lewthwaite, Dennis Jensen
Summary: In healthy younger adults, using two separate single-item rating scales to assess breathlessness during CPET is feasible and allows for the distinct sensory intensity and affective dimensions of exertional breathlessness to be evaluated.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Physiology
Kathrin Rottermann, Annika Weigelt, Tim Staebler, Benedikt Ehrlich, Sven Dittrich, Isabelle Schoeffl
Summary: This study compares the results of a mobile device-based outdoor running test with a treadmill test. The results show that the outdoor test is significantly shorter in duration and yields higher values for almost all cardiopulmonary variables. Testing very young children with a mobile device is a new alternative that allows for individualized and standardized exercise testing.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Critical Care Medicine
Thomas W. DeCato, Hans C. Haverkamp, Thomas Gooding, Dave S. Collingridge, Matthew J. Hegewald
Summary: This study assessed the long-term variability of VO2, VCO2, and VE during biocontrol testing. The results showed that these measurements exhibited certain levels of variation under steady-state conditions over a one-year period. Utilizing +/- 1.96 z-scores allows one to determine if a result exceeds expected variability, which may warrant investigation of the instrument.
Article
Cardiac & Cardiovascular Systems
Erik H. Van Iterson, Leslie Cho, Adriano Tonelli, J. Emanuel Finet, Luke J. Laffin
Summary: In patients with HFrEF, demonstrating a restrictive pattern on spirometry yields the severest mortality risk associated with (V) over dotO(2peak). Using spirometry to screen patients with HFrEF for ventilatory defects has a potential role in improving risk stratification based on (V) over dotO(2peak).
Article
Pediatrics
T. Goddard, S. Sonnappa
Summary: CPET is a non-invasive, reproducible method for assessing cardiovascular, ventilatory, and metabolic responses to exercise, used to determine exercise capacity and personalized interventions in children. EID can be caused by various factors, requiring different treatments for each cause.
PAEDIATRIC RESPIRATORY REVIEWS
(2021)
Article
Cardiac & Cardiovascular Systems
Simon Wernhart, Maria Papathanasiou, Amir Abbas Mahabadi, Tienush Rassaf, Peter Luedike
Summary: Beta blockers (BB) have an impact on exercise capacity and oxygen uptake efficiency slope (OUES) in heart failure with preserved ejection fraction (HFpEF) patients. BB has a significant effect on the high-risk group but not on the low-risk group. Direct quantification of O 2 pulse may improve the discrimination of HFpEF patients.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Anesthesiology
Vladimir Bolshinsky, Hilmy Ismail, Michael Li, Jarrod Basto, Robert Schier, Anna Hagemeier, Kwok-Ming Ho, Alexander Heriot, Bernhard Riedel
Summary: This pilot study explores the impact of preoperative covariates and traditional cardiopulmonary exercise testing (CPET)-derived parameters on postoperative outcomes after major colorectal cancer surgery. The study found that low preoperative haemoglobin, low albumin, or high neutrophil count were associated with postoperative complications and reduced overall survival. Gas exchange parameters focusing on VCO2 kinetics and correcting peakVO2 to body surface area could improve CPET-derived preoperative risk assessment. Inflammatory parameters also added significant predictive value to preoperative risk assessment.
PERIOPERATIVE MEDICINE
(2022)
Article
Surgery
Riccardo Orlandi, Rocco Francesco Rinaldo, Alessandra Mazzucco, Andrea Baccelli, Michele Mondoni, Francesca Marchetti, Mariapia Zagaria, Jacopo Cefalo, Andrea Leporati, Matteo Montoli, Giorgio Ghilardi, Alessandro Baisi, Stefano Centanni
Summary: The study aims to evaluate postoperative outcomes of low-risk patients and compare them with patients without pulmonary impairment.
FRONTIERS IN SURGERY
(2023)