The novel, orally bioavailable HSP90 inhibitor NVP-HSP990 induces cell cycle arrest and apoptosis in multiple myeloma cells and acts synergistically with melphalan by increased cleavage of caspases
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Title
The novel, orally bioavailable HSP90 inhibitor NVP-HSP990 induces cell cycle arrest and apoptosis in multiple myeloma cells and acts synergistically with melphalan by increased cleavage of caspases
Authors
Keywords
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Journal
EUROPEAN JOURNAL OF HAEMATOLOGY
Volume 88, Issue 5, Pages 406-415
Publisher
Wiley
Online
2012-02-07
DOI
10.1111/j.1600-0609.2012.01764.x
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- (2009) O. Landgren et al. BLOOD
- Caspases and Kinases in a Death Grip
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- International Myeloma Working Group molecular classification of multiple myeloma: spotlight review
- (2009) R Fonseca et al. LEUKEMIA
- Myeloma Bone Disease: Recent Advances in Biology, Diagnosis, and Treatment
- (2009) O. Sezer ONCOLOGIST
- Heat Shock Protein 90 as a Drug Target: Some Like It Hot
- (2008) U. Banerji CLINICAL CANCER RESEARCH
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- Serum concentrations of DKK-1 decrease in patients with multiple myeloma responding to anti-myeloma treatment
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- (2008) C Jakob et al. LEUKEMIA
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- (2007) Monica Hecht et al. EXPERIMENTAL CELL RESEARCH
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