APR-246 exhibits anti-leukemic activity and synergism with conventional chemotherapeutic drugs in acute myeloid leukemia cells

Genes of cell-cell interactions, chemotherapy detoxification and apoptosis are induced during chemotherapy of acute myeloid leukemia

(2009) Anne Margrete Øyan et al.   BMC CANCER

PRIMA-1 Reactivates Mutant p53 by Covalent Binding to the Core Domain

(2009) Jeremy M.R. Lambert et al.   CANCER CELL

Comprehensive analysis of cooperative gene mutations between class I and class II inde novoacute myeloid leukemia

(2009) Yuichi Ishikawa et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Low p14ARF expression inde novoacute myeloid leukemia with normal karyotype is associated with poor survival

(2009) Esbjörn Paul et al.   LEUKEMIA & LYMPHOMA

PRIMA-1MET induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 protein

(2009) György Stuber et al.   Molecular Cancer

Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis

(2009) J M R Lambert et al.   ONCOGENE

Mutated and non-mutated TP53 as targets in the treatment of leukaemia

(2008) H. Nahi et al.   BRITISH JOURNAL OF HAEMATOLOGY

Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype

(2008) C Haferlach et al.   LEUKEMIA