Article
Immunology
Yufeng Wang, Chunxu Wang, Nan Zuo, Hao Yang, Shaohong Fang, Jialan Shi
Summary: This study investigates the role of ETs in endothelial injury in APL and suggests that targeting ETs production may be an effective approach for relieving vascular leakage and reducing the burden of bleeding.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Oncology
Bernice L. Z. Oh, Shawn H. R. Lee, Koon M. Foo, Kean H. Chiew, Zelia Z. L. Seeto, Zhi W. Chen, Cheryl C. C. Neoh, Germaine S. M. Liew, Jing J. Eng, Joyce C. M. Lam, Yiong H. Chan, Thuan C. Quah, Ah M. Tan, Allen E. J. Yeoh
Summary: In non-high-risk acute lymphoblastic leukaemia patients, replacing doxorubicin/cytarabine with vincristine/asparaginase during some delayed-intensification blocks has effectively reduced toxicity and decreased hospital admissions for fever, allowing for earlier completion of treatment phase without compromising outcomes.
EUROPEAN JOURNAL OF CANCER
(2021)
Article
Computer Science, Information Systems
Xiaohuan Wu, Weihua Dong, Lun Wu, Yu Liu
Summary: This research conducts a bibliometric analysis of 9400 publications between 1991 and 2020 in order to understand the development progress of GIScience. The results show that certain research themes are growing rapidly while others are decreasing. The study also suggests several research directions for future attention.
INTERNATIONAL JOURNAL OF GEOGRAPHICAL INFORMATION SCIENCE
(2023)
Article
Gastroenterology & Hepatology
Nirav Thosani, Shahrooz Rashtak, Bijun Sai Kannadath, Akhil Munjal, Matthew Meriwether, Eric D. Yoon, Andrew Hermann, Sara Ali, Paul G. Haddad, Prithvi Patil, Srinivas Ramireddy, Ricardo Badillo, R. Tomas DaVee, Sushovan Guha
Summary: The study found that the risk of significant bleeding associated with PEG placement was minimal in patients on uninterrupted periprocedural antithrombotic therapy. There were only a few cases of significant bleeding events and PEG-related mortality in the study cohort.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Oncology
Anselm Tamminen, Tuomas Huttunen, Tuomo Meretoja, Laura Niinikoski, Ilkka Koskivuo
Summary: This study evaluated the rate of postoperative bleeding and other surgical complications in mastectomy between ultrasonic scissors and traditional electrocautery. The results showed that the rate of postoperative bleeding complications was lower in patients operated with ultrasonic scissors, and the rate of surgical site infections was similar between the two instruments. Additionally, the rate of skin flap necrosis was also lower in the ultrasonic scissors group.
Article
Oncology
Harinder Gill, Radha Raghupathy, Carmen Y. Y. Lee, Yammy Yung, Hiu-Tung Chu, Michael Y. Ni, Xiao Xiao, Francis P. Flores, Rita Yim, Paul Lee, Lynn Chin, Vivian W. K. Li, Lester Au, Wing-Yan Au, Edmond S. K. Ma, Diwakar Mohan, Cyrus Rustam Kumana, Yok-Lam Kwong
Summary: This study found that the incidence of acute promyelocytic leukaemia (APL) is increasing, and the use of oral arsenic trioxide (oral-ATO) in treatment has significantly improved patient survival rates.
Article
Medicine, General & Internal
Mohammed Issa, Karl L. Kiening, Andreas W. Unterberg, Moritz Scherer, Alexander Younsi, Stepan Fedorko, Rod J. Oskouian, Jens R. Chapman, Basem Ishak
Summary: This study retrospectively analyzed 15 patients over 90 years of age who underwent CT-guided posterior stabilization for unstable odontoid type II fractures, showing that the surgical treatment is safe and effective with low complications and mortality rates. The average follow-up time was 36 months.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Hematology
Sandy On, Carolyn G. Rath, Michelle Lan, Bobby Wu, Kimberly M. Lau, Edna Cheung, William Alegria, Rebecca Young, Marisela Tan, Carrie Kim, Jennifer Phun, Nimish Patel, Gabriel Mannis, Aaron C. Logan, Vanessa Kennedy, Aaron Goodman, Randy A. Taplitz, Patricia A. Young, Raymond Wen, Ila M. Saunders
Summary: This study investigated the incidence of invasive fungal infections and other infectious complications in patients with acute myeloid leukaemia receiving venetoclax and hypomethylating agent therapy. The results showed a low incidence of IFIs, but an increase in bacterial infections and hospital admissions due to neutropenic fever.
BRITISH JOURNAL OF HAEMATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Yasutoshi Shiratori, Naoki Ishii, Tomonori Aoki, Katsumasa Kobayashi, Atsushi Yamauchi, Atsuo Yamada, Jun Omori, Taiki Aoyama, Naoyuki Tominaga, Yoshinori Sato, Takaaki Kishino, Tsunaki Sawada, Masaki Murata, Akinari Takao, Kazuhiro Mizukami, Ken Kinjo, Shunji Fujimori, Takahiro Uotani, Minoru Fujita, Hiroki Sato, Sho Suzuki, Toshiaki Narasaka, Junnosuke Hayasaka, Tomohiro Funabiki, Yuzuru Kinjo, Akira Mizuki, Shu Kiyotoki, Tatsuya Mikami, Ryosuke Gushima, Hiroyuki Fujii, Yuta Fuyuno, Naohiko Gunji, Yosuke Toya, Kazuyuki Narimatsu, Noriaki Manabe, Koji Nagaike, Tetsu Kinjo, Yorinobu Sumida, Sadahiro Funakoshi, Kiyonori Kobayashi, Tamotsu Matsuhashi, Yuga Komaki, Kuniko Miki, Kazuhiro Watanabe, Kazuki Yamamoto, Takaaki Yoshimoto, Ayaka Takasu, Takashi Ikeya, Fumio Omata, Katsuyuki Fukuda, Mitsuru Kaise, Naoyoshi Nagata
Summary: This study aimed to determine the optimal timing of colonoscopy for acute lower GI bleeding and factors that benefit patients. The results showed that early colonoscopy identified recent bleeding better and reduced hospital stay, but it also carried an increased risk of rebleeding within 30 days. Early colonoscopy was particularly beneficial for patients with a shock index >= 1 or poor performance status at presentation.
GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Marilia Carabotti, Antonio M. Morselli Labate, Cesare Cremon, Rosario Cuomo, Fabio Pace, Paolo Andreozzi, Francesca Falangone, Giovanni Barbara, Bruno Annibale
Summary: This study of 1,217 patients found that those with previous acute diverticulitis were younger with a higher family history of diverticular disease, while those with previous diverticular bleeding had a higher prevalence of chronic obstructive pulmonary disease compared to uncomplicated diverticular disease and diverticulitis. These distinct features could help improve the assessment of risk factors for diverticular complications.
DIGESTIVE AND LIVER DISEASE
(2021)
Article
Gastroenterology & Hepatology
Scheifer Carole, Luckina Elena, Lebrun-Vignes Benedicte, Diop Abdoul-Aziz, Damais-Thabut Dominique, Damien Roos Weil, Dechartres Agnes, Lebray Pascal
Summary: This study aimed to investigate the relationship between the use of oral anti-HCV Direct Acting Antivirals (DAA) treatment and the occurrence of hematological malignancies (HM) in patients with chronic HCV infection. The results showed that the incidence of acute myeloid leukemia (AML) appeared to be higher after DAA treatments, especially in severe HCV patients, including those with cirrhosis and/or liver transplants.
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
(2022)
Article
Pediatrics
Tianyan Hu, Belene Podmore, Rosemarie Barnett, Dominik Beier, Wolfgang Galetzka, Nawab Qizilbash, Dennis Haeckl, Jessica Weaver, Timo Boellinger, Sarah Mihm, Tanaz Petigara
Summary: The incidence of AOM in children under 16 years old in Germany has decreased following the introduction of PCV13, with significant declines in all age groups. However, there has been an increase in complicated AOM cases while the incidence of AOM-related surgical procedures remained constant.
Review
Pediatrics
Melissa Gabriel, Bianca A. W. Hoeben, Hilde Hylland Uhlving, Olga Zajac-Spychala, Anita Lawitschka, Dorine Bresters, Marianne Ifversen
Summary: Despite advancements in hematopoietic stem cell transplant techniques, the risk of neurological complications remains significant, especially for children and adolescents. The impact of neurotoxic drugs, radiotherapy, and neurological complications on the developing brain is still not fully understood. Further research is needed to determine the sensitivity of the nervous system to toxic insults and the long-term effects of these complications on children and adolescents.
FRONTIERS IN PEDIATRICS
(2021)
Article
Multidisciplinary Sciences
Anna Graipe, Anders Ulvenstam, Anna-Lotta Irevall, Lars Soderstrom, Thomas Mooe
Summary: Bleeding complications post ACS, particularly gastrointestinal bleeding, were frequent in this study. Older age, lower baseline hemoglobin, hypertension, and heart failure were predictive factors for bleeding events. Importantly, bleeding independently predicted increased mortality.
SCIENTIFIC REPORTS
(2021)
Article
Hematology
Tabea Sutter, Marcus Schittenhelm, Thomas Volken, Thomas Lehmann
Summary: The objective of this study was to investigate the impact of treatment choice on survival, transfusion needs, and hospitalizations in patients over 64 years old with newly diagnosed AML. Retrospective analysis of patients diagnosed with AML between 2017 and 2020 in a regional healthcare network in Switzerland revealed that patients in the HMA + VEN treatment group had significantly better overall survival, shorter hospital stays, and lower transfusion needs.
