MECHANISMS IN ENDOCRINOLOGY: Ghrelin: the differences between acyl- and des-acyl ghrelin

Ghrelin: An emerging new anticonvulsant neuropeptide

(2012) Jeanelle Portelli et al.   EPILEPSIA

Metabolic effects of overnight continuous infusion of unacylated ghrelin in humans

(2012) A. Benso et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Ghrelin Protects H9c2 Cardiomyocytes From Angiotensin II–induced Apoptosis Through the Endoplasmic Reticulum Stress Pathway

(2012) Chunyan Yang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Des-Acyl Ghrelin Fragments and Analogues Promote Survival of Pancreatic β-Cells and Human Pancreatic Islets and Prevent Diabetes in Streptozotocin-Treated Rats

(2012) Riccarda Granata et al.   JOURNAL OF MEDICINAL CHEMISTRY

Des-acyl ghrelin exhibits pro-anabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats

(2012) Sulaiman Sheriff et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Acylated and unacylated ghrelin attenuate isoproterenol-induced lipolysis in isolated rat visceral adipocytes through activation of phosphoinositide 3-kinase γ and phosphodiesterase 3B

(2011) Alessandra Baragli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Unacylated ghrelin is associated with changes in body composition and body fat distribution during long-term exercise intervention

(2011) Henna Cederberg et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Mouse ghrelin-O-acyltransferase (GOAT) plays a critical role in bile acid reabsorption

(2011) Kihwa Kang et al.   FASEB JOURNAL

Ghrelin: A gut hormonal basis of motility regulation and functional dyspepsia

(2011) Kazuma Ogiso et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Lack of direct effects of acyl ghrelin, des-acyl ghrelin, and obestatin on rat lower esophageal sphincter motility in vitro

(2011) Chih-Yen Chen et al.   Journal of the Chinese Medical Association

The Relationship Between Serum Ghrelin and the Risk of Gastric and Esophagogastric Junctional Adenocarcinomas

(2011) G. Murphy et al.   JNCI-Journal of the National Cancer Institute

The Peptidic GHS-R antagonist [D-Lys3]GHRP-6 markedly improves adiposity and related metabolic abnormalities in a mouse model of postmenopausal obesity

(2011) L. Maletínská et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Ghrelin and cancer

(2011) Lisa Chopin et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Ghrelin receptor as a novel imaging target for prostatic neoplasms

(2011) Chen Lu et al.   PROSTATE

Unacylated Ghrelin Rescues Endothelial Progenitor Cell Function in Individuals With Type 2 Diabetes

(2010) G. Togliatto et al.   DIABETES

Des-Acyl Ghrelin Has Specific Binding Sites and Different Metabolic Effects from Ghrelin in Cardiomyocytes

(2010) Pamela V. Lear et al.   ENDOCRINOLOGY

Ectopic recombination in the central and peripheral nervous system byaP2/FABP4-Cremice: Implications for metabolism research

(2010) Katrin Martens et al.   FEBS LETTERS

Changes in Acyl Ghrelin, Des-acyl Ghrelin, and Ratio of Acyl Ghrelin to Total Ghrelin with Short-term Refeeding in Female Inpatients with Restricting-type Anorexia Nervosa

(2010) K.-I. Koyama et al.   HORMONE AND METABOLIC RESEARCH

Effect of desacyl ghrelin, obestatin and related peptides on triglyceride storage, metabolism and GHSR signaling in 3T3-L1 adipocytes

(2010) Pierre Miegueu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Gastric metaplasia of the duodenum: In vivo diagnosis by endomicroscopy and its relationship with functional dyspepsia

(2010) Rui Ji et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Unacylated Ghrelin Rapidly Modulates Lipogenic and Insulin Signaling Pathway Gene Expression in Metabolically Active Tissues of GHSR Deleted Mice

(2010) Patric J. D. Delhanty et al.   PLoS One

Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin

(2010) Rajesh Kumar et al.   REGULATORY PEPTIDES

Glucose and Weight Control in Mice with a Designed Ghrelin O-Acyltransferase Inhibitor

(2010) B. P. Barnett et al.   SCIENCE

Acylated and nonacylated ghrelin levels and their associations with insulin resistance in obese and normal weight children with metabolic syndrome

(2009) Lucia Pacifico et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes

(2009) A Rodríguez et al.   INTERNATIONAL JOURNAL OF OBESITY

Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone

(2008) Jing Yang et al.   CELL

Effect of Des-acyl Ghrelin on Adiposity and Glucose Metabolism

(2008) Weizhen Zhang et al.   ENDOCRINOLOGY

Des-acyl ghrelin fragments evoke endothelium-dependent vasodilatation of rat mesenteric vascular bed via activation of potassium channels

(2008) Banafsheh Moazed et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ghrelin octanoylation mediated by an orphan lipid transferase

(2008) J. A. Gutierrez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice

(2008) Kenneth A. Longo et al.   REGULATORY PEPTIDES

Ghrelin as a pleotrophic modulator of gonadal function and reproduction

(2008) Manuel Tena-Sempere   Nature clinical practice. Endocrinology & metabolism