Epistatic interactions between thiopurine methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) variations determine 6-mercaptopurine toxicity in Indian children with acute lymphoblastic leukemia

Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing

(2011) M V Relling et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Determinants of mercaptopurine toxicity in paediatric acute lymphoblastic leukemia maintenance therapy

(2010) Tiphaine Adam de Beaumais et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Thiopurine S-methyltransferase gene polymorphism and 6-mercaptopurine dose intensity in Indian children with acute lymphoblastic leukemia

(2010) Gauri Kapoor et al.   LEUKEMIA RESEARCH

Frequency of TPMT alleles in Indian patients with acute lymphatic leukemia and effect on the dose of 6-mercaptopurine

(2009) Salamun Desire et al.   MEDICAL ONCOLOGY

Characterization of the Inosine Triphosphatase (ITPA) Gene: Haplotype Structure, Haplotype-Phenotype Correlation and Promoter Function

(2009) Nicolas von Ahsen et al.   THERAPEUTIC DRUG MONITORING

Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease

(2008) A. ANSARI et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Thiopurine-Induced Myelotoxicity in Patients With Inflammatory Bowel Disease: A Review

(2008) Javier P. Gisbert et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Highly Multiplexed Genotyping of Thiopurine S-Methyltransferase Variants Using MALDI-TOF Mass Spectrometry: Reliable Genotyping in Different Ethnic Groups

(2008) E. Schaeffeler et al.   CLINICAL CHEMISTRY

Genetic Polymorphism of Inosine Triphosphate Pyrophosphatase Is a Determinant of Mercaptopurine Metabolism and Toxicity During Treatment for Acute Lymphoblastic Leukemia

(2008) G Stocco et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Thiopurine S-methyltransferase activity in three major Asian populations: a population-based study in Singapore

(2008) Shirley Kow Yin Kham et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Functional characterization of 23 allelic variants of thiopurine S-methyltransferase gene (TPMT*2 – *24)

(2008) Shuta Ujiie et al.   Pharmacogenetics and Genomics