Innovative study design for paediatric clinical trials

Bayesian design using adult data to augment pediatric trials

(2009) David A Schoenfeld et al.   Clinical Trials

Stopping trials for efficacy: an almost unbiased view

(2009) Steven N Goodman   Clinical Trials

Antiepileptic Drug Development in Children

(2009) Catherine Chiron et al.   DRUGS

Sequential design with boundaries approach in pediatric intervention research reduces sample size

(2009) Johanna H. van der Lee et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial

(2008) Nicolino Ruperto et al.   LANCET

Adalimumab with or without Methotrexate in Juvenile Rheumatoid Arthritis

(2008) Daniel J. Lovell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adaptive design methods in clinical trials – a review

(2008) Shein-Chung Chow et al.   Orphanet Journal of Rare Diseases