Article
Cardiac & Cardiovascular Systems
Martin B. Leon, Michael J. Mack, Rebecca T. Hahn, Vinod H. Thourani, Raj Makkar, Susheel K. Kodali, Maria C. Alu, Mahesh V. Madhavan, Katherine H. Chau, Mark Russo, Samir R. Kapadia, S. Chris Malaisrie, David J. Cohen, Philipp Blanke, Jonathon A. Leipsic, Mathew R. Williams, James M. McCabe, David L. Brown, Vasilis Babaliaros, Scott Goldman, Howard C. Herrmann, Wilson Y. Szeto, Philippe Genereux, Ashish Pershad, Michael Lu, John G. Webb, Craig R. Smith, Philippe Pibarot
Summary: In low surgical risk patients with symptomatic severe aortic stenosis, the PARTNER 3 trial showed superiority of transcatheter aortic valve replacement (TAVR) over surgery for the primary endpoint at 1 year. However, at 2 years, differences in death and stroke between TAVR and surgery were no longer significant, and TAVR patients had an increased risk of valve thrombosis.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Mahesh V. Madhavan, Susheel K. Kodali, Vinod H. Thourani, Raj Makkar, Michael J. Mack, Samir Kapadia, John G. Webb, David J. Cohen, Howard C. Herrmann, Mathew Williams, Kevin Greason, Philippe Pibarot, Rebecca T. Hahn, Wael Jaber, Ke Xu, Maria Alu, Craig R. Smith, Martin B. Leon
Summary: This study compared the 5-year risk-adjusted outcomes of S3 TAVR and SAVR in intermediate-risk patients and found similar rates of death and disabling stroke between the two procedures. However, the incidence of paravalvular regurgitation was higher after S3 TAVR.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Amgad Mentias, Marwan Saad, Milind Y. Desai, Amar Krishnaswamy, Venu Menon, Phillip A. Horwitz, Samir Kapadia, Mary Vaughan Sarrazin
Summary: The study compared outcomes of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in patients with rheumatic aortic stenosis (AS), as well as TAVR in nonrheumatic AS. The results showed similar mortality rates between TAVR and SAVR for rheumatic AS patients, suggesting that TAVR could be a viable alternative to traditional surgery in this patient population.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
John K. Forrest, G. Michael Deeb, Steven J. Yakubov, Hemal Gada, Mubashir A. Mumtaz, Basel Ramlawi, Tanvir Bajwa, Paul S. Teirstein, Michael DeFrain, Murali Muppala, Bruce J. Rutkin, Atul Chawla, Bart Jenson, Stanley J. Chetcuti, Robert C. Stoler, Marie-France Poulin, Kamal Khabbaz, Melissa Levack, Kashish Goel, Didier Tchetche, Ka Yan Lam, Pim A. L. Tonino, Saki Ito, Jae K. Oh, Jian Huang, Jeffrey J. Popma, Neal Kleiman, Michael J. Reardon, Low Risk Trial Investigators
Summary: This study evaluated the clinical and echocardiographic outcomes of transcatheter aortic valve replacement (TAVR) compared with surgery in low-risk patients at 3 years. It found that TAVR showed durable benefits compared with surgery in terms of reducing the incidence of all-cause mortality or disabling stroke, and also significantly improved valve hemodynamics in patients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Robert B. Hawkins, G. Michael Deeb, Devraj Sukul, Himanshu J. Patel, Sarah K. Gualano, Stanley J. Chetcuti, P. Michael Grossman, Gorav Ailawadi, Shinichi Fukuhara
Summary: This study found that there is a higher risk associated with redo surgery after transcatheter aortic valve replacement (TAVR), and the number of patients requiring reoperation after TAVR is increasing. Therefore, patients with a longer life expectancy and unsuitable anatomy for redo-TAVR should consider surgical aortic valve replacement (SAVR) as the first-line treatment option.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Yousif Ahmad, James P. Howard, Ahran D. Arnold, Mahesh V. Madhavan, Christopher M. Cook, Maria Alu, Michael J. Mack, Michael J. Reardon, Vinod H. Thourani, Samir Kapadia, Hans Gustav Horsted Thyregod, Lars Sondergaard, Troels Hojsgaard Jorgensen, William D. Toff, Nicolas M. Van Mieghem, Raj R. Makkar, John K. Forrest, Martin B. Leon
Summary: A meta-analysis comparing TAVI with SAVR in lower-risk patients showed a lower risk of death and death or disabling stroke at 1 year with TAVI. However, there were no significant differences in main outcomes between the two procedures in higher-risk patients.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Daniel O'Hair, Steven J. Yakubov, Kendra J. Grubb, Jae K. Oh, Saki Ito, G. Michael Deeb, Nicolas M. Van Mieghem, David H. Adams, Tanvir Bajwa, Neal S. Kleiman, Stanley Chetcuti, Lars Sondergaard, Hemal Gada, Mubashir Mumtaz, John Heiser, William M. Merhi, George Petrossian, Newell Robinson, Gilbert H. L. Tang, Joshua D. Rovin, Stephen H. Little, Renuka Jain, Sarah Verdoliva, Tim Hanson, Shuzhen Li, Jeffrey J. Popma, Michael J. Reardon
Summary: This study aimed to evaluate the 5-year incidence and clinical outcomes of hemodynamic structural valve deterioration (SVD) in patients undergoing self-expanding transcatheter aortic valve implantation (TAVI) or surgery. The results showed a lower rate of SVD in the TAVI group and its association with worse clinical outcomes.
Article
Cardiac & Cardiovascular Systems
John K. Forrest, G. Michael Deeb, Steven J. Yakubov, Joshua D. Rovin, Mubashir Mumtaz, Hemal Gada, Daniel O'Hair, Tanvir Bajwa, Paul Sorajja, John C. Heiser, William Merhi, Abeel Mangi, Douglas J. Spriggs, Neal S. Kleiman, Stanley J. Chetcuti, Paul S. Teirstein, George L. Zorn, Peter Tadros, Didier Tchetche, Jon R. Resar, Antony Walton, Thomas G. Gleason, Basel Ramlawi, Ayman Iskander, Ronald Caputo, Jae K. Oh, Jian Huang, Michael J. Reardon
Summary: The complete 2-year follow-up from the Evolut Low Risk Trial found that TAVR is noninferior to surgery for the primary endpoint of all-cause mortality or disabling stroke.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Nazli Okumus, Sonu Abraham, Rishi Puri, W. H. Wilson Tang
Summary: This review comprehensively examines the phenotypes of AS in the context of HF progression and explores the evolving role of TAVR in specific populations.
JACC-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Mathew R. Williams, Hasan Jilaihawi, Raj Makkar, William W. O'Neill, Robert Guyton, S. Chris Malaisrie, David L. Brown, Philipp Blanke, Jonathon A. Leipsic, Philippe Pibarot, Rebecca T. Hahn, Martin B. Leon, David J. Cohen, Jeroen J. Bax, Susheel K. Kodali, Michael J. Mack, Michael Lu, John G. Webb
Summary: This study compares 1-year outcomes between TAVR patients with BAV and TAV morphology. The results show that TAVR with the SAPIEN 3 device demonstrates similar outcomes to TAV patients in low-surgical-risk, severe aortic stenosis cases.
JACC-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Medicine, General & Internal
Taishi Okuno, Caglayan Demirel, Daijiro Tomii, Gabor Erdoes, Dik Heg, Jonas Lanz, Fabien Praz, Rainer Zbinden, David Reineke, Lorenz Raber, Stefan Stortecky, Stephan Windecker, Thomas Pilgrim
Summary: This study aimed to evaluate the risk of noncardiac surgery after TAVI. The results suggest that noncardiac surgery can be performed early after successful TAVI, and device performance may impact the risk of adverse outcomes after surgery.
Article
Cardiac & Cardiovascular Systems
Amr E. Abbas, Julien Ternacle, Philippe Pibarot, Ke Xu, Maria Alu, Erin Rogers, Rebecca T. Hahn, Martin Leon, Vinod H. Thourani
Summary: Severe PPM is more common following SAVR compared with TAVR and only affects mortality in patients with LF following TAVR and LF and low ejection fraction following SAVR, while severe PPM in normal flow is not associated with poor outcomes.
CIRCULATION-CARDIOVASCULAR IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Tadeja Kolar, Nikola Lakic, Alesa Kotnik, David Stubljar, Zlatko Fras, Matjaz Bunc
Summary: This study compared the outcomes of transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) in octogenarians. The results showed similar clinical outcomes in terms of clinical endpoints in low- and medium-risk groups, but differences were observed in certain indicators such as paravalvular leak, acute kidney injury, and new onset atrial fibrillation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Flavien Vincent, Julien Ternacle, Tom Denimal, Mylene Shen, Bjorn Redfors, Cedric Delhaye, Matheus Simonato, Nicolas Debry, Basile Verdier, Bahira Shahim, Thibault Pamart, Hugues Spillemaeker, Guillaume Schurtz, Francois Pontana, Vinod H. Thourani, Philippe Pibarot, Eric Van Belle
Summary: TAVR is rapidly expanding its indications, but faces technical challenges and knowledge gaps when dealing with patients with bicuspid aortic valve (BAV). Physicians need to understand the BAV anatomy and TAVR procedure planning comprehensively to guide treatment decisions.
Article
Medicine, General & Internal
You Mi Hwang, Jun Kim, Gi Byoung Nam, Kee Joon Choi, Duk-Woo Park, Do-Yoon Kang, Seung-Jung Park, Seo Young Park
Summary: The study found a higher incidence of pacemaker dependency after TAVR compared to SAVR, with 58.6% of post-TAVR PPI patients no longer being pacemaker-dependent after 1 year.
Article
Cardiac & Cardiovascular Systems
Fabiola B. Sozzi, Laura Iacuzio, Filippo Civaia, Ciro Canetta, Frederic Berthier, Stephane Rusek, Philippe Rossi, Federico Lombardi, Gilles Dreyfus, Vincent Dor
AMERICAN HEART JOURNAL
(2015)
Review
Cardiac & Cardiovascular Systems
Vito Maurizio Parato, Valeria Antoncecchi, Fabiola Sozzi, Stefania Marazia, Annapaola Zito, Maria Maiello, Pasquale Palmiero
CARDIOVASCULAR ULTRASOUND
(2016)
Review
Cardiac & Cardiovascular Systems
Fabiola B. Sozzi, Maria Maiello, Francesco Pelliccia, Vito Maurizio Parato, Ciro Canetta, Ketty Savino, Federico Lombardi, Pasquale Palmiero
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
(2016)
Editorial Material
Cardiac & Cardiovascular Systems
Fabiola B. Sozzi, Nicolas Hugues, Filippo Civaia, Clara Alexandrescu, Laura Iacuzio
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2017)
Editorial Material
Cardiac & Cardiovascular Systems
Fabiola B. Sozzi, Nicolas Hugues, Laura Iacuzio, Francois Bourlon
EUROPEAN HEART JOURNAL
(2017)
Article
Cardiac & Cardiovascular Systems
Fabiola B. Sozzi, Filippo Civaia, Philippe Rossi, Jean-Francois Robillon, Stephane Rusek, Frederic Berthier, Francois Bourlon, Laura Iacuzio, Gilles Dreyfus, Vincent Dor
AMERICAN JOURNAL OF CARDIOLOGY
(2011)
Article
Endocrinology & Metabolism
Jors N. van der Sijde, Henk J. Boiten, Fabiola B. Sozzi, Abdou Elhendy, Ron T. van Domburg, Arend F. L. Schinkel
Editorial Material
Cardiac & Cardiovascular Systems
Fabiola B. Sozzi, Francois Bourlon, Filippo Civaia, Philippe Rossi, Armand Eker, Stephane Rusek, Laura Iacuzio, Vincent Dor
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
(2010)
Article
Cardiac & Cardiovascular Systems
Fabiola B. Sozzi, Armand Eker, Francois Bourlon, Yacoub Habib, Filippo Civaia, Clara Alexandrescu, Gilles Dreyfus, Vincent Dor
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
(2014)
Article
Surgery
R. Ferraresi, A. Palloshi, G. Aprigliano, C. Caravaggi, M. Centola, F. Sozzi, G. B. Danzi, M. Manzi
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2012)
Editorial Material
Cardiac & Cardiovascular Systems
Emanuele Catena, Fabiola Sozzi, Salvatore Trunfio, Elisa Montrasio, Sandra Nonini, Giuseppe Tarelli
JOURNAL OF CARDIOVASCULAR MEDICINE
(2010)
Meeting Abstract
Cardiac & Cardiovascular Systems
F. B. Sozzi, L. Iacuzio, C. Canetta, F. Civaia, F. Berthier, P. Rossi, S. Rusek, F. Lombardi, G. Dreyfus, V. Dor
EUROPEAN HEART JOURNAL
(2014)
Article
Cardiac & Cardiovascular Systems
A. Campanile, F. B. Sozzi, D. Consonni, F. Piscione, P. Sganzerla, C. Indolfi, A. Stabile, A. Migliorini, D. Antoniucci, R. Ferraresi, G. Boccuzzi, G. B. Danzi
MINERVA CARDIOANGIOLOGICA
(2014)
Article
Cardiac & Cardiovascular Systems
Alfonso Campanile, Fabiola B. Sozzi, Ciro Canetta, Gian Battista Danzi
EXPERIMENTAL & CLINICAL CARDIOLOGY
(2013)
