Review
Oncology
Zhi Liang, Xiaobiao Song, Jiang Hu, Riga Wu, Pengda Li, Zhenyu Dong, Lu Liang, Jijun Wang
Summary: This meta-analysis suggests that the consumption of fermented dairy foods, especially cheese and yogurt, may be associated with a decreased risk of colorectal cancer.
FRONTIERS IN ONCOLOGY
(2022)
Article
Gastroenterology & Hepatology
Zhen-Ying Wu, Jia-Li Chen, Han Li, Ke Su, Yun-Wei Han
Summary: A meta-analysis of existing studies found that higher intake of citrus, apples, watermelon, and kiwi was associated with a reduced risk of colorectal cancer (CRC), while the intake of other types of fruits showed no significant association. Citrus intake showed a non-linear dose-response relationship with CRC risk, with the risk minimized at a daily intake of 120g.
WORLD JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Nutrition & Dietetics
Wei Qi Loh, Jiyoung Youn, Wei Jie Seow
Summary: There is conflicting evidence regarding the association between vitamin E intake and prostate cancer risk. This meta-analysis found little evidence for a beneficial effect of vitamin E intake on prostate cancer risk overall, but suggests that supplements may have a protective effect in certain conditions.
Review
Nutrition & Dietetics
Long Shu, Yiqian Huang, Caijuan Si, Qin Zhu, Peifen Zheng, Xiaoyan Zhang
Summary: This systematic review and meta-analysis examined the association between ultra-processed food (UPF) intake and colorectal cancer (CRC) risk. The results showed that high intake of UPF was significantly associated with increased risk of CRC, particularly in case-control studies and developed countries. However, further large prospective cohort studies are needed to confirm these findings.
FRONTIERS IN NUTRITION
(2023)
Review
Food Science & Technology
Yue Li, Mingjun Sun
Summary: The meta-analysis found no association between cholesterol consumption and colorectal cancer in cohort studies when comparing high vs low intake categories and assessing dose-response relationship. However, significant associations were found in case-control studies. Additional prospective cohort studies are needed to confirm these findings.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Nutrition & Dietetics
Hyeonmin Gil, Qiao-Yi Chen, Jaewon Khil, Jihyun Park, Gyumi Na, Donghoon Lee, Nana Keum
Summary: A meta-analysis of observational studies found that milk intake during childhood and adolescence may not be associated with risks of breast, prostate, and colorectal cancer later in life. More studies are needed to reach a definitive conclusion.
Article
Pharmacology & Pharmacy
Jie Wang, Jing Gao, Hong-li Xu, Ying Qian, Li Xie, Herbert Yu, Bi-yun Qian
Summary: This study found a negative association between Citrus fruit intake and lung cancer risk. Moreover, there was a nonlinear dose-response relationship between Citrus intake and lung cancer risk within a certain range.
PHARMACOLOGICAL RESEARCH
(2021)
Review
Multidisciplinary Sciences
Christos Markellos, Maria-Eleni Ourailidou, Maria Gavriatopoulou, Panagiotis Halvatsiotis, Theodoros N. Sergentanis, Theodora Psaltopoulou
Summary: This study found an association between olive oil consumption and a lower risk of cancer and better prognosis. Higher olive oil consumption was correlated with a decreased likelihood of developing any cancer, breast cancer, gastrointestinal cancer, upper aerodigestive cancer, and urinary tract cancer.
Article
Nutrition & Dietetics
Xuechen Chen, Michael Hoffmeister, Hermann Brenner
Summary: This study aimed to assess the impact of high red and processed meat intake (RPMI) on colorectal cancer (CRC) risk and compare it with genetically determined risk. The study found that RPMI increases CRC risk regardless of genetic risk. Avoiding RPMI can compensate for a substantial proportion of polygenic risk for CRC.
Review
Oncology
Hongmei Hua, Qiuping Jiang, Pan Sun, Xing Xu
Summary: This study conducted a systematic review and meta-analysis of 36 studies to identify risk factors for early-onset colorectal cancer (EOCRC). The results showed that male, Caucasian, family history of CRC, inflammatory bowel disease, obesity, hypertension, smoking, and alcohol consumption were associated with increased risk of EOCRC. Sedentary lifestyle, high intake of red meat, processed meat, Western dietary patterns, and sugar-sweetened beverages were also associated with increased risk. Vitamin D may be a protective factor. These findings provide important information for risk prediction models and tailored screening strategies for EOCRC.
FRONTIERS IN ONCOLOGY
(2023)
Review
Nutrition & Dietetics
Qie Reng, Ling Ling Zhu, Li Feng, Yong Jie Li, Yan Xing Zhu, Ting Ting Wang, Feng Jiang
Summary: This study conducted a systematic review and meta-analysis to investigate the association between meat mutagens and cancer risk. The results showed that the intake of PhIP, MeIQx, DiMeIQx, and total HCA was significantly associated with an increased risk of cancer, while the intake of B(a)P did not show a significant association with cancer risk.
FRONTIERS IN NUTRITION
(2022)
Review
Nutrition & Dietetics
Bo Wu, Dehua Yang, Shuhan Yang, Guangzhe Zhang
Summary: High intakes of salt, pickled food, and processed meat are significantly associated with increased risks of gastric cancer, even when moderate amounts of salt are consumed.
FRONTIERS IN NUTRITION
(2021)
Review
Gastroenterology & Hepatology
Dylan E. O'Sullivan, R. Liam Sutherland, Susanna Town, Kristian Chow, Jeremy Fan, Nauzer Forbes, Steven J. Heitman, Robert J. Hilsden, Darren R. Brenner
Summary: This study identified significant risk factors for early-onset colorectal cancer, including family history of colorectal cancer, hyperlipidemia, obesity, and alcohol consumption. Smoking was suggestive but not statistically significant as a risk factor. Other potential risk factors such as hypertension, metabolic syndrome, ulcerative colitis, and occupational exposure to organic dusts were also identified in limited studies. High-quality studies on generalizable populations are needed to further explore risk factors for early-onset colorectal cancer and inform prevention strategies.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Review
Oncology
Hatim Boughanem, Silvia Canudas, Pablo Hernandez-Alonso, Nerea Becerra-Tomas, Nancy Babio, Jordi Salas-Salvado, Manuel Macias-Gonzalez
Summary: Vitamin D intake is associated with the prevention of colorectal cancer (CRC), showing a significant lower risk in case-control studies. However, larger and high-quality prospective studies and clinical trials are needed to confirm this association.
Review
Surgery
A. L. Ebbehoj, L. N. Jorgensen, P-M Krarup, H. G. Smith
Summary: This study reviewed the association between histopathological findings and lymph node metastases in T1 colorectal cancer, finding that factors such as lymphovascular invasion, tumor budding, and depth of submucosal invasion were associated with LNMs. These distinct histopathological factors can help in selecting patients for local excision or major excisional surgery.
BRITISH JOURNAL OF SURGERY
(2021)