Article
Multidisciplinary Sciences
Yue Gong, Yifei Wang, Du Chen, Feng Xu, Peng Yang
Summary: This study found that hyperglycemia is associated with increased mortality and hematoma expansion in patients with intracerebral hemorrhage. The hyperglycemic group had higher rates of hematoma expansion and larger hematoma volumes compared to the normoglycemic group. Multivariate logistic analysis showed that blood glucose is an independent predictor of hematoma expansion.
Article
Clinical Neurology
Jing Wang, Lu Zhou, Yuanyuan Chen, Hongli Zhou, Yuanxin Tan, Weijia Zhong, Zhiming Zhou
Summary: A nomogram model based on noncontrast computed tomography (NCCT) was developed and validated to predict the short-term prognosis of Chinese patients with hypertensive intracerebral hemorrhage (HICH). Four models were established using radiomics and logistic regression analyses, with the combined model showing the best predictive performance. A radiomics-clinical (R-C) nomogram was visualized and demonstrated satisfactory calibration and clinical value.
FRONTIERS IN NEUROLOGY
(2023)
Article
Clinical Neurology
Sae-Yeon Won, Johannes Walter, Silvia Hernandez-Duran, Obada T. Alhalabi, Bedjan Behmanesh, Joshua D. Bernstock, Marcus Czabanka, Nazife Dinc, Daniel Dubinski, Charlotte Flueh, Thomas M. Freiman, Anne S. Grosch, Eva Herrmann, Young Sill Kang, Juergen Konczalla, Andreas Kramer, Felix Lehmann, Johannes Lemcke, Ruzanna Melkonian, Dorothee Mielke, Lukas Mueller, Florian Ringel, Veit Rohde, Matthias Schneider, Christian Senft, Patrick Schuss, Merih Oznur Turgut, Michael Synowitz, Joana M. Ullmann, Hartmut Vatter, Klaus Zweckberger, Fatma Kilinc, Florian Gessler
Summary: This study aims to validate the ICH and ICH-GS scores in patients with cerebellar hemorrhage and compare the outcomes of surgical management with conservative treatment. The results showed that both ICH and ICH-GS scores have good prognostic accuracy for overall mortality and functional outcomes. Surgical management was beneficial for patients with severe cerebellar hemorrhages, indicated by high ICH scores, while conservative treatment was reasonable for patients with lower ICH scores. Therefore, ICH and ICH-GS scores are useful tools for predicting survival and outcome in cerebellar ICH patients.
Article
Clinical Neurology
Sijia Li, Yu Wang, Wenjuan Wang, Qian Zhang, Anxin Wang, Xingquan Zhao
Summary: This study investigates the impact of stress hyperglycemia on clinical outcomes in patients with spontaneous intracerebral hemorrhage using the glucose-to-glycated hemoglobin (HbA1c) ratio. The results indicate that higher glucose-to-HbA1c ratio is independently associated with worse functional outcomes at discharge and 90 days in these patients.
Review
Medicine, General & Internal
Xin-Ni Lv, Zuo-Qiao Li, Qi Li
Summary: Intracerebral hemorrhage is a dangerous subtype of stroke with high rates of morbidity and mortality. Targeting prevention of hematoma growth and perihematomal edema expansion shows promise as a therapeutic approach. Blood-based biomarkers are being studied as potential diagnostic, predictive, and prognostic markers due to their accessibility and acceptance in clinical practice. Validation studies are needed to determine the usefulness of these biomarkers in the future.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Jian Zhang, Chunlong Liu, Yaofeng Hu, Aoran Yang, Yonghui Zhang, Yang Hong
Summary: This study retrospectively collected baseline characteristics and laboratory findings of spontaneous intracerebral hemorrhage patients undergoing surgery, and found that high neutrophil-to-lymphocyte ratio (NLR) within 48 hours after surgery was an independent risk factor for poor prognosis at 30 days post-operation.
FRONTIERS IN NEUROLOGY
(2023)
Article
Neurosciences
Jiawen Li, Dong Luo, Feifei Peng, Qi Kong, Huawei Liu, Meiyuan Chen, Lusha Tong, Feng Gao
Summary: The novel ANAID-ICH nomogram, incorporating age, NIHSS score, anemia, infratentorial location, presence of DWILs, and prior ICH, may facilitate the identification of patients at higher risk for an unfavorable outcome.
CNS NEUROSCIENCE & THERAPEUTICS
(2022)
Article
Clinical Neurology
Edward R. Bader, Tiberiu A. Pana, Raphae S. Barlas, Anthony K. Metcalf, John F. Potter, Phyo K. Myint
Summary: This study investigates the association between admission inflammatory biomarkers and adverse outcomes in spontaneous intracerebral hemorrhage (ICH) using a stroke register in the United Kingdom. The results show that elevated inflammatory biomarkers are associated with poor outcomes in ICH, highlighting the importance of inflammation in this condition.
JOURNAL OF NEUROLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Andrea Morotti, Giorgio Busto, Gregoire Boulouis, Elisa Scola, Alessandro Padovani, Ilaria Casetta, Enrico Fainardi
Summary: The combined analysis of non-contrast CT and CT perfusion markers improves the prediction of hematoma expansion and outcome in intracerebral hemorrhage.
EUROPEAN RADIOLOGY
(2023)
Article
Medicine, Research & Experimental
Xiao-Yu Wu, Yao-Kun Zhuang, Yong Cai, Xiao-Qiao Dong, Ke-Yi Wang, Quan Du, Wen-Hua Yu
Summary: The serum glucose/potassium ratio (GPR) is a potential prognostic predictor for acute brain injury-related diseases, and is weakly correlated with the NIHSS score, GCS score, and hematoma volume. It is independently associated with poor outcomes and significantly improves the prognostic predictive capability of hematoma volume.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2021)
Article
Critical Care Medicine
Valentina Mazzoleni, Alessandro Padovani, Andrea Morotti
Summary: Acute intracerebral hemorrhage is a serious medical emergency with high mortality and morbidity rates. Neuroimaging plays a crucial role in diagnosing the cause, monitoring patients, and assessing the risk of hematoma expansion and poor outcomes. Lowering blood pressure and reversing coagulopathy are the mainstays of medical treatment during the acute phase, with the goal of preventing hematoma expansion. The efficacy of these therapies is time-dependent and has a narrow time window. This review provides an update on the etiological diagnostic workup, acute treatment, and prognosis of intracerebral hemorrhage.
JOURNAL OF CRITICAL CARE
(2023)
Article
Clinical Neurology
Lindsey R. Kuohn, Jens Witsch, Thorsten Steiner, Kevin N. Sheth, Hooman Kamel, Babak B. Navi, Alexander E. Merkler, Santosh B. Murthy, Stephan A. Mayer
Summary: This study examined the relationship between different locations (deep versus lobar) of intracerebral hemorrhage (ICH) and early neurological deterioration, hematoma expansion (HE), and outcome. The results showed that lobar ICH location was associated with more common HE and early neurological deterioration, while deep ICH location was associated with smaller hematoma size. However, after adjusting for prognostic variables, deep ICH was associated with worse outcome.
Review
Neurosciences
Hongxiu Guo, Mingfeng You, Jiehong Wu, Anqi Chen, Yan Wan, Xinmei Gu, Senwei Tan, Yating Xu, Quanwei He, Bo Hu
Summary: This article summarizes the current knowledge of genetic variations in spontaneous intracerebral hemorrhage (ICH), with a focus on location distribution and outcome. Investigations have shown that certain genetic variants are associated with lobar ICH or deep ICH, and some variations in genes may contribute to the outcome of ICH.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Clinical Neurology
Zachary Troiani, Luis Ascanio, Christina P. Rossitto, Muhammad Ali, Nicki Mohammadi, Shahram Majidi, J. Mocco, Christopher P. Kellner
Summary: The study identified inflammatory and neuron and astrocyte-specific biomarker categories as having the greatest number of significant individual biomarker predictors of long-term outcomes. Further investigation is warranted to validate the predictive utility of biomarkers in patients with intracerebral hemorrhage.
NEUROREHABILITATION AND NEURAL REPAIR
(2021)
Article
Clinical Neurology
ZhiMing Zhou, ZuHua Song, Yuanyuan Chen, Jinhua Cai
Summary: A radiomics-clinical nomogram was developed to predict the short-term prognosis of patients with deep intracerebral hemorrhage (DICH). The nomogram showed good discrimination and clinical applicability in different cohorts, utilizing radiomics features and clinical factors for prediction.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Negar Morovatdar, Mario Di Napoli, Saverio Stranges, Amanda G. Thrift, Moira Kapral, Reza Behrouz, Mohammad Taghi Farzadfard, Mohammad Sobhan Sheikh Andalibi, Reza Rahimzadeh Oskooie, Anuradha Sawant, Naghmeh Mokhber, M. Reza Azarpazhooh
Summary: This study found that among stroke patients, inactive individuals were younger at the age of first stroke occurrence and had a higher risk of mortality at 1 and 5 years compared to active individuals, while other outcomes did not show significant differences.
NEUROLOGICAL SCIENCES
(2021)
Letter
Clinical Neurology
Flavio Di Stasio, Martina Fanella, Marianna Brienza, Giuliano Gentili, Mario Di Napoli
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
(2021)
Review
Clinical Neurology
Sasan Andalib, Jose Biller, Mario Di Napoli, Narges Moghimi, Louise D. McCullough, Clio A. Rubinos, Christa O'Hana Nobleza, M. Reza Azarpazhooh, Luciana Catanese, Isabel Elicer, Mostafa Jafari, Fabrizio Liberati, Claudia Camejo, Michel Torbey, Afshin A. Divani
Summary: This review discusses the peripheral nervous system manifestations associated with COVID-19, including nerve pain, muscle injury, Guillain-Barre syndrome, and other disorders. COVID-19 not only affects the central nervous system but also involves the PNS, potentially due to immune system dysregulation.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
(2021)
Review
Environmental Sciences
Francesco Fisicaro, Mario Di Napoli, Aldo Liberto, Martina Fanella, Flavio Di Stasio, Manuela Pennisi, Rita Bella, Giuseppe Lanza, Gelsomina Mansueto
Summary: The current research on the neuropathology of COVID-19 deceased patients is still limited, focusing on vascular-related and infection-related inflammatory tissue damage. However, it is currently unclear whether these findings are the result of direct viral pathology or the non-specific impact of cardiovascular and pulmonary diseases on the brain.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Neurosciences
Elaheh Zarean, Simona Lattanzi, Mehdi Azizmohammad Looha, Mario Di Napoli, Sherry H-Y Chou, Alibay Jafarli, Michel Torbey, Afshin A. Divani
Summary: The study evaluated the association between glycemic gap (GG) and in-hospital mortality in patients with intracerebral hemorrhage (ICH). GG was found to be an independent predictor of in-hospital mortality and showed better predictive performance in diabetic patients compared to admission glucose levels. Admission GG may serve as a useful prognostic biomarker for ICH patients with diabetes.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2021)
Article
Clinical Neurology
Negar Morovatdar, Abolfazl Avan, M. Reza Azarpazhooh, Mario Di Napoli, Saverio Stranges, Moira K. Kapral, Arash Akhavan Rezayat, Aidin Shariatzadeh, Shahram Abootalebi, Naghmeh Mokhber, J. David Spence, Vladimir Hachinski
Summary: From 1990 to 2017, the age-standardized burden of IHD, stroke, and dementia decreased, more prominently in OECD countries than the world. However, their rising crude numbers mainly due to population growth and ageing require urgent identification of reversible risk and protective factors.
NEUROLOGICAL SCIENCES
(2022)
Article
Environmental Sciences
Monica Singh, Srishti Valecha, Rubanpal Khinda, Nitin Kumar, Surinderpal Singh, Pawan K. Juneja, Taranpal Kaur, Mario Di Napoli, Jatinder S. Minhas, Puneetpal Singh, Sarabjit Mastana
Summary: This study aimed to investigate whether a combination of significant risk variables, pro-inflammatory markers, and candidate genes could serve as a predictive marker for knee osteoarthritis (KOA). The study identified higher BMI, triglycerides, poor sleep, IL-6, IL-1 beta, and hsCRP as independent predictors for KOA. Additionally, specific haplotypes within CRP, IL-6, VDR, and eNOS genes were found to impact KOA risk, further enhancing the predictive ability of the model.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Neurosciences
Simona Lattanzi, Davide Norata, Afshin A. Divani, Mario Di Napoli, Serena Broggi, Chiara Rocchi, Santiago Ortega-Gutierrez, Gelsomina Mansueto, Mauro Silvestrini
Summary: This study aimed to evaluate the relationship between systemic inflammatory response index (SIRI) and futile recanalization in patients with AIS. The study found that older age, higher admission National Institutes of Health stroke scale score, and higher admission SIRI increased the risk of poor outcomes at 3 months despite complete or near-complete recanalization.
Review
Clinical Neurology
Gelsomina Mansueto, Giuseppe Lanza, Francesco Fisicaro, Danielle Alaouieh, Emily Hong, Sara Girolami, Marco Montella, Alessandro Feola, Mario Di Napoli
Summary: This review provides a comprehensive update on the clinical assessment, diagnosis, complications, and treatment of PCNSV. Recent developments and advances in technology have improved diagnostic accuracy and provided new insights for preventing misdiagnosis. However, treatment for PCNSV remains largely empirical.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
(2022)
Article
Genetics & Heredity
Nitin Kumar, Manminder Kaur, Gurjinderpal Singh, Srishti Valecha, Rubanpal Khinda, Mario DiNapoli, Monica Singh, Puneetpal Singh, Sarabjit Mastana
Summary: This study explores the genetic implications of NLRP3 inflammasome in ischemic stroke (IS) in Punjab. It finds that certain SNPs and haplotypes within the NLRP3 gene are associated with an increased risk of IS, and this risk is linked to higher levels of systolic blood pressure and pro-inflammatory markers.
INTERNATIONAL JOURNAL OF IMMUNOGENETICS
(2022)
Review
Medicine, General & Internal
Diana L. L. Alsbrook, Mario Di Napoli, Kunal Bhatia, Masoom Desai, Archana Hinduja, Clio A. A. Rubinos, Gelsomina Mansueto, Puneetpal Singh, Gustavo G. G. Domeniconi, Asad Ikram, Sara Y. Y. Sabbagh, Afshin A. A. Divani
Summary: This review article provides an up-to-date understanding of the pathophysiology of DCI and its association with EBI in aSAH patients. Recent studies have shown that EBI plays a crucial role in the development of DCI, and advanced monitoring and neuroimaging techniques can help detect EBI and improve clinical management.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Immunology
Puneetpal Singh, Nitin Kumar, Monica Singh, Manminder Kaur, Gurjinderpal Singh, Amit Narang, Abhinav Kanwal, Kirti Sharma, Baani Singh, Mario Di Napoli, Sarabjit Mastana
Summary: Atherosclerosis is the formation of plaque within arteries, caused by the accumulation of fats, cholesterol, and fibrous material, leading to blockage of blood flow and ischemia. It has a significant impact on global health statistics, being the main cause of morbidity and mortality for diseases such as rheumatological, heart, and brain disorders. Inflammation and coagulatory mediators contribute to the development and worsening of atherosclerotic plaque, with neutrophil extracellular traps and NLRP3 playing a significant role in this process. This review focuses on the contribution of these two processes in atherosclerosis, inflammation, and atherothrombosis.
Review
Clinical Neurology
Ylenia Pastorello, Roxana O. Carare, Claudia Banescu, Lawrence Potempa, Mario Di Napoli, Mark Slevin
Summary: Circulating C-reactive protein (pCRP) concentrations significantly increase during acute and chronic infection and disease, playing a role in complement fixation. It is now known that pCRP dissociates into the monomeric form (mCRP) when exposed to activated immune cells or damaged tissue, becoming biologically active. Studies have shown that mCRP is distributed within the brain tissue of individuals with neuroinflammatory disease and has been linked to neurovascular dysfunction, blood brain barrier compromise, and increased risk of dementia. Future therapeutic options aim to inhibit pCRP-LPC mediated dissociation and prevent associated damage.
Review
Clinical Neurology
Gelsomina Mansueto, Giuseppe Lanza, Jessica Falleti, Pasquale Orabona, Danielle Alaouieh, Emily Hong, Sara Girolami, Marco Montella, Francesco Fisicaro, Anna Galdieri, Puneetpal Singh, Mario Di Napoli
Summary: This review provides a comprehensive update on the clinical assessment, diagnosis, complications, treatment, and follow-up of peripheral nervous system vasculitides (PNSV). Recent advancements in neuroimaging, molecular testing, and peripheral nerve biopsy have improved the clinical assessment and diagnostic accuracy of PNSV. The identification of specific morphological findings has improved the differentiation between systemic and non-systemic neuropathies, leading to more accurate diagnoses and proper management.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
(2023)
Meeting Abstract
Clinical Neurology
Afshin Divani, Xi Liu, Alexander Petersen, Craig Anderson, Elaheh Zarean, Simona Lattanzi, Wendy Ziai, Michel Torbey, Tom Moullaali, Alibay Jafarli, Michael James, Stephan Mayer, Jose Suarez, Claude Hemphill, Mario Di Napoli
Article
Neurosciences
Adam Vacek, Grant Mair, Philip White, Philip M. Bath, Keith W. Muir, Rustam Al-Shahi Salman, Chloe Martin, David Dye, Francesca M. Chappell, Ruediger von Kummer, Malcolm Macleod, Nikola Sprigg, Joanna M. Wardlaw
Summary: This study evaluated the performance of e-ASPECTS software in delineating the extent of intracranial hemorrhage (ICH) on brain CT scans. The results showed that the software achieved excellent or good delineation of ICH extent in 71% of cases. However, it was more likely to over- or under-estimate the extent when ICH was more extensive, intraventricular, or extra-axial.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Mathias Jacobsen Bach, Audrone Jakubauskaite, Ian Law, Otto Molby Henriksen, Inger Havsteen, Alexander Cuculiza Henriksen, Sverre Rosenbaum, Lisbeth Marner
Summary: This study found that the rCBFacz value after ACZ challenge can serve as an important indicator for predicting future cerebrovascular events, with high accuracy and prognostic value.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Tak Kyu Oh, Saeyeon Kim, In-Ae Song
Summary: The study found that many survivors of nontraumatic intracranial hemorrhage in South Korea experience unemployment, decreased household income, and newly acquired disability after intensive care unit admission. However, these changes are not associated with 2-year all-cause mortality.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Eduardo Sousa de Melo, Rodrigo de Paiva Bezerra, Arthur Cesario de Holanda, Maria Junia Lira e Silva, Paloma Peter Travassos, Tayne Fernanda Lemos da Silva, Genova Maria de Azevedo Oliveira, Silvia Marinho Martins Alves, Carolina de Araujo Medeiros, Maria das Neves Dantas da Silveira Barros, Wilson Alves de Oliveira, Gisele Sampaio Silva, Luciana Patrizia Alves de Andrade Valenca
Summary: Cardiac involvement has been found to be the predominant factor correlated with stroke in Chagas disease. While atherosclerosis-related risk factors are prevalent, their influence on ischemic stroke in Chagas disease appears limited.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Pingping Zheng, Ning Zhang, Zixi Chen
Summary: This case presents a rare infectious cause of stroke and air embolism involving a pulmonary abscess and pulmonary vein thrombosis. Early detection, diagnosis, and appropriate treatment of infected systemic embolism in young patients are crucial to prevent serious complications.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Filippo Luca Gurgoglione, Luigi Vignali, Maria Alberta Cattabiani, Emilia Solinas, Giorgio Benatti, Iacopo Tadonio, Federico Barocelli, Chiara Dizdari, Domenico Tuttolomondo, Diego Ardissino, Francesco Nicolini, Giampaolo Niccoli
Summary: The incidence of recurrent ischemic neurological events after transcatheter patent foramen ovale closure is relatively low. Obesity, Risk of Paradoxical Embolism score < 7, and migraine are independent positive predictors of recurrent stroke or transient ischemic attack.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Angelo Cascio Rizzo, Ghil Schwarz, Amedeo Cervo, Giuditta Giussani, Chiara Ceresa, Antonella Gatti, Fausto De Angeli, Cristina Motto, Angelo Guccione, Rachele Tortorella, Giuseppe Granata, Claudia Rollo, Antonio Macera, Mariangela Piano, Guglielmo Pero, Elio Clemente Agostoni
Summary: This study aimed to evaluate the efficacy and safety of endovascular treatment (EVT) in primary and EVT-induced secondary medium-vessel occlusions (MeVO). The results showed that primary MeVO had poorer outcomes in terms of complications, EVT efficacy, and the proportion of patients with a modified Rankin Scale (mRS) of 0-2 at 3 months compared to exclusive large-vessel occlusion (LVO). However, EVT-induced secondary MeVO showed similar safety and efficacy outcomes as exclusive LVO and had better outcomes in terms of mRS 0-2 compared to primary MeVO.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jing Zhang, Chenming Wei, Jian Wu
Summary: This case report describes a patient with Bloom syndrome who developed acute cerebral infarction along with elevated antiphospholipid antibodies, suggesting a possible association between immune and coagulation abnormalities caused by Bloom syndrome and the development of acute cerebral infarction.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Yunxia Zhou, Shenglan He, Yanhong Hu
Summary: Compared with clopidogrel, DAPT with ticagrelor plus aspirin was associated with significantly lower thromboembolic events without an increase in hemorrhagic events in the treatment of intracranial aneurysms, according to the one-year clinical outcome analysis. However, larger upcoming trials are needed to confirm the effectiveness and safety of ticagrelor-associated DAPT.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Edvania Andrade de Moura Silva, Ludmilla Ribeiro Batista, Marcela Aline Fernandes Braga, Luci Fuscaldi Teixeira-Salmela, Christina Danielli Coelho de Morais Faria, Iza Faria-Fortini
Summary: The study found that stroke severity is the best predictor of self-perceived manual ability at both three and six months after stroke. Age, although significant, contributes little to the prediction of manual ability.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Sidarrth Prasad, Erica M. Jones, Mehari Gebreyohanns, Veronica Aguilera, DaiWai M. Olson, Jane A. Anderson, Sean I. Savitz, Salvador C. Flores, Steven J. Warach, Charlotte E. Rhodes, Mark P. Goldberg, Nneka L. Ifejika
Summary: This study identified the barriers and facilitators to adopting tenecteplase (TNK) as a thrombolytic treatment for acute ischemic stroke (AIS) by conducting qualitative research with stroke clinicians in Texas. The findings suggest that providing evidence and identifying key change processes can help clinicians achieve consensus on adopting TNK for AIS treatment.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jeshma Jayan, Sunil K. Narayan, Yasmin Nesha Haniffa, Navin Kumar
Summary: This study investigated the effects of transcranial electrical and magnetic stimulation on somatosensory evoked potentials in chronic ischemic stroke patients, finding that the real tDCS and rTMS combination results in significant improvement and is safe for use.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Phoebe M. Tran, Cenjing Zhu, William T. Harris II, Sajeesh K. Kamala Raghavan, Agricola Odoi, Liem Tran
Summary: This study assessed the geographic accessibility of stroke rehabilitation facilities in Tennessee. The study found that rural counties had significantly longer travel distances and times compared to urban counties. Counties with high and medium stroke prevalence also had higher travel times and distances compared to low stroke prevalence counties. Therefore, addressing transportation barriers and implementing tele-rehabilitation are crucial for improving access to stroke aftercare in these areas.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Lili Xu, Shuaiyu Chen, Jing Xu, Yanyan Shi, Zhihang Huang, Meng Wang, Ziqiao Wei, Hui Cao, Junshan Zhou, Wei Wang, Mingyang Du
Summary: This study found that the Chinese Visceral Adiposity Index (CVAI) is positively correlated with 90-day poor outcome in Chinese ischemic stroke patients after endovascular thrombectomy (EVT).
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Guangying Wu, Shuhua Li, Min Luo, Xiaotian Li, Xinghua Zhu, Junhuai Zhang, Qian He, Qian Yang, Guojiang Zhao, Shasha Luo, Zhijie Yang
Summary: The study aimed to investigate the relationship between serum alkaline phosphatase (ALP) levels and the severity and prognosis of intracerebral hemorrhage (ICH). The results showed that serum ALP levels in ICH patients were significantly elevated and correlated with hematoma volume and Glasgow coma scale (GCS) score. High serum ALP levels may serve as a potential predictor for the severity and unfavorable prognosis of ICH.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)