Article
Oncology
Mate Szilcz, Jonas W. Wastesson, Lucas Morin, Amaia Calderon-Larranaga, Mats Lambe, Kristina Johnell
Summary: This study aimed to identify quality indicators of overtreatment at the end of life among older adults with solid cancer, finding that about one-third of decedents received potentially overtreatment during their last month of life.
Article
Oncology
Ana Paula de Souza Franco, Eric Renato Lima Figueiredo, Giovana Salomao Melo, Josiel de Souza e Souza, Nelson Veiga Goncalves, Fabiana de Campos Gomes, Joao Simao de Melo Neto
Summary: This study aims to identify sociodemographic and risk factors associated with higher testicular cancer mortality and poorer survival rates, while examining the impact of diagnostic and treatment procedures on reducing mortality. The retrospective ecological study analyzed mortality data from testicular cancer in Brazil from 2001 to 2020. Data revealed an increasing trend in mortality after 2011 among persons born after 1976 in the 15-40 age group.
Review
Clinical Neurology
Sepehr Khosravi, Amirmahdi Khayyamfar, Milad Shemshadi, Masoud Pourghahramani Koltapeh, Mohsen Sadeghi-Naini, Zahra Ghodsi, Farhad Shokraneh, Mohadeseh Sarbaz Bardsiri, Pegah Derakhshan, Khalil Komlakh, Alex R. Vaccaro, Michael G. Fehlings, James D. Guest, Vanessa Noonan, Vafa Rahimi-Movaghar
Summary: The scoping review identified 87 quality of care indicators for individuals with traumatic spinal cord injury, covering assessment of healthcare system structure, medical processes, and outcomes related to spinal cord injury.
GLOBAL SPINE JOURNAL
(2022)
Article
Nursing
Shantelle Smith, Daniel Sapkaroski, Margaret Brand, Anh Tran, John Zalcberg, Robert G. Stirling
Summary: This retrospective cohort study analyzed the clinical care pathways of Stage III-IV non-small cell lung cancer patients in Victoria based on the Optimal Care Pathway recommendations. The study found unwarranted variations in the implementation of supportive care and palliative care, with higher utilization of palliative care at the time of treatment rather than early after diagnosis. The findings highlight the importance of multidisciplinary meetings and early supportive care screening in improving communication and integration of palliative care into routine clinical practice.
NURSING & HEALTH SCIENCES
(2023)
Article
Clinical Neurology
Abdel Douiri, Walter Muruet, Ajay Bhalla, Martin James, Lizz Paley, Kaili Stanley, Anthony G. Rudd, Charles D. A. Wolfe, Benjamin D. Bray
Summary: The initial wave of the COVID-19 pandemic in the UK led to a decrease in admissions for acute stroke patients, with older patients and those with less severe strokes being more affected. While quality of stroke care was maintained and even improved in some aspects, there was an increase in inpatient case fatality, especially among patients with confirmed or suspected COVID-19 infections. These findings suggest that hospital avoidance during the pandemic may have resulted in untreated stroke patients with poorer outcomes, highlighting the need for resilient healthcare systems.
Article
Oncology
Mariana Brandao, Diogo Martins-Branco, Claudia De Angelis, Peter Vuylsteke, Richard D. Gelber, Nancy Van Damme, Lien van Walle, Arlindo R. Ferreira, Matteo Lambertini, Francesca Poggio, Didier Verhoeven, Annelore Barbeaux, Francois P. Duhoux, Hans Wildiers, Carmela Caballero, Ahmad Awada, Martine Piccart-Gebhart, Kevin Punie, Evandro de Azambuja
Summary: Among patients with de novo metastatic breast cancer who received systemic treatment and survived for nine months or more, those who underwent surgery of the primary tumor within nine months of diagnosis had longer overall survival compared to those who did not.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Article
Oncology
Saeed Nemati, Elnaz Saeedi, Fereshte Lotfi, Azin Nahvijou, Habbiballah Pirnejad, Maria Cheraghi, Abbas Rezaeianzadeh, Roya Dolatkhah, Azam Bazarafshan, Arash Golpazir, Majid Yaghoobi-Ashrafi, Sepideh Abdi, Saba Alvand, Zahra Ravankhah, Elham Mohebbi, Ardeshir Khosravi, Arash Etemadi, Mahdi Sheikh, Gholamreza Roshandel, Ali Ghanbari-Motlagh, Elham Partovipour, Farid Najafi, Reza Malekzadeh, Mohammad Ali Mohagheghi, Kazem Zendehdel
Summary: This study investigated the geographical disparity in cancer survival in different provinces of Iran. The results showed significant differences in survival rates between regions for different cancer types, with less disparity for lethal cancers. Compared to Tehran, the highest excess hazard of death was found in Western Azerbaijan, Kermanshah, and Kerman provinces. Provinces with higher HDI had better survival rates, indicating the importance of human development for cancer patients' outcomes.
CANCER EPIDEMIOLOGY
(2023)
Article
Urology & Nephrology
Benjamin V. Stone, Jacob E. Tallman, Kelvin A. Moses
Summary: The study found that treatment of adrenocortical carcinoma at an academic center is associated with improved overall survival compared to community programs. Academic centers had more aggressive surgical treatment practices, and the survival benefit persisted even after controlling for treatment modality in multivariable analysis.
JOURNAL OF UROLOGY
(2021)
Article
Public, Environmental & Occupational Health
Anita Andreano, Maria Grazia Valsecchi, Antonio Giampiero Russo, Salvatore Siena
Summary: A set of 34 indicators for guideline-concordant care in lung cancer was selected and evaluated by a multidisciplinary panel of clinicians. Out of 22 feasible indicators, 16 were retained after assessing criterion validity and were further evaluated for reliability. The developed set of indicators is now available for implementing and monitoring quality initiatives for lung cancer care.
ARCHIVES OF PUBLIC HEALTH
(2021)
Review
Clinical Neurology
Anna Kristina Kraft, Klaus Berger
Summary: This review identified six quality indicators for the assessment of care for patients with MS, based on evidence from 6 sources and a total of 226 quality indicators. Out of these, 147 indicators were included in the assessment, and the six identified indicators describe five important characteristics of high-quality care for MS patients.
FRONTIERS IN NEUROLOGY
(2021)
Review
Clinical Neurology
Anna Kristina Kraft, Klaus Berger
Summary: A review identified six reports with a total of 226 quality indicators for MS care. After assessment, 147 indicators were included, with six high-quality indicators describing important characteristics of high-quality care for MS patients. These findings provide a starting point for the development of comprehensive sets of quality indicators in MS.
FRONTIERS IN NEUROLOGY
(2021)
Review
Oncology
Marta Maes-Carballo, Yolanda Gomez-Fandino, Ayla Reinoso-Hermida, Carlos Roberto Estrada-Lopez, Manuel Martin-Diaz, Khalid Saeed Khan, Aurora Bueno-Cavanillas
Summary: The study identified 89 QIs from 22 selected documents, covering various aspects of breast cancer care. Most countries have not established national clinical pathways or integrated health care processes for breast cancer care, leading to heterogeneity in QIs for evaluating care quality.
Article
Oncology
Benjamin V. Stone, Stephen C. Hill, Kelvin A. Moses
Summary: The study revealed significant differences in survival rates for urethral cancer patients based on treating facilities. Academic centers tended to use more complex multimodal treatments, radical surgeries, and regional lymphadenectomies during treatment processes.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2021)
Article
Medicine, Research & Experimental
Yelda A. Leal, Javier Torres, Ricardo Gamboa, Alejandra Mantilla-Morales, Patricia Pina-Sanchez, Oscar Arrieta, Laura Bonifaz, Abelardo Meneses, Celida Duque, Marion Pineros
Summary: This article presents the first results of the Merida population-based cancer registry in Mexico over a four-year period. The main incident cancers were prostate and breast cancer, while cervical cancer had high incidence rates among women. Further exploration is needed for lymphomas and liver cancer data.
ARCHIVES OF MEDICAL RESEARCH
(2022)
Review
Medicine, General & Internal
Davis Kibirige, Nyasatu Chamba, Irene Andia-Biraro, Kajiru Kilonzo, Sweetness Naftal Laizer, Isaac Sekitoleko, Andrew Peter Kyazze, Sandra Ninsiima, Phillip Ssekamatte, Felix Bongomin, Lucy Elauteri Mrema, Willyhelmina Olomi, Theodora D. Mbunda, Nyanda Elias Ntinginya, Issa Sabi, Katrina Sharples, Philip Hill, Lindsey Te Brake, Josephine VandeMaat, Reinout VanCrevel, Julia Alison Critchley
Summary: There is a lack of contemporary data on the attainment of optimal diabetes treatment goals and the burden of diabetes complications in adult populations with type 2 diabetes in Africa. This study aimed to document the current status of attainment of key indicators of optimal diabetes care and the prevalence of diabetes complications in this population. The findings suggest that achieving optimal treatment goals, especially for HbA1c, remains a challenge in adult patients with type 2 diabetes in Africa. Diabetes complications, particularly diabetic peripheral neuropathy and retinopathy, are highly prevalent.
Article
Oncology
S. Stordeur, J. Vlayen, F. Vrijens, C. Camberlin, C. De Gendt, E. Van Eycken, T. Lerut
EUROPEAN JOURNAL OF CANCER CARE
(2015)
Article
Nutrition & Dietetics
Dominique Roberfroid, Lieven Huybregts, Carl Lachat, France Vrijens, Patrick Kolsteren, Benjamin Guesdon
Article
Public, Environmental & Occupational Health
S. Stordeur, F. Vrijens, R. Leroy
REVUE D EPIDEMIOLOGIE ET DE SANTE PUBLIQUE
(2016)
Article
Oncology
L. Verleye, C. De Gendt, F. Vrijens, V. Schillemans, C. Camberlin, G. Silversmit, S. Stordeur, E. Van Eycken, C. Dubois, J. Robays, I. Wauters, J. P. Van Meerbeeck
EUROPEAN JOURNAL OF CANCER CARE
(2018)
Article
Oncology
C. Dubois, H. De Schutter, R. Leroy, S. Stordeur, C. De Gendt, V. Schillemans, L. Kohn, L. Van Eycken, F. Vrijens
EUROPEAN JOURNAL OF CANCER CARE
(2018)
Article
Health Care Sciences & Services
France Vrijens, Cindy De Gendt, Leen Verleye, Jo Robays, Viki Schillemans, Cecile Camberlin, Sabine Stordeur, Cecile Dubois, Elisabeth Van Eycken, Isabelle Wauters, Jan P. Van Meerbeeck
INTERNATIONAL JOURNAL FOR QUALITY IN HEALTH CARE
(2018)
Article
Public, Environmental & Occupational Health
F. Vrijens, F. Hulstaert, S. Devriese, S. Van De Sande
EPIDEMIOLOGY AND INFECTION
(2012)
Article
Health Care Sciences & Services
France Vrijens, Francoise Renard, Pascale Jonckheer, Koen Van den Heede, Anja Desomer, Carine Van de Voorde, Denise Walckiers, Cecile Dubois, Cecile Camberlin, Joan Vlayen, Herman Van Oyen, Christian Leonard, Pascal Meeus
Article
Cardiac & Cardiovascular Systems
Danielle Strens, An Colle, France Vrijens, Dominique Paulus, Maria Eyssen, Hans Van Brabandt, Ilse Van Vlaenderen
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2013)
Article
Oncology
David Jegou, Cecile Dubois, Viki Schillemans, Sabine Stordeur, Cindy De Gendt, Cecile Camberlin, Leen Verleye, France Vrijens
Article
Oncology
Viki Schillemans, France Vrijens, Cindy De Gendt, Jo Robays, Geert Silversmit, Leen Verleye, Cecile Camberlin, Cecile Dubois, Sabine Stordeur, Isabelle Wauters, Jan P. Van Meerbeeck, Elizabeth Van Eycken, Paul De Leyn
Article
Medicine, Research & Experimental
Hilde Nevens, Jillian Harrison, France Vrijens, Leen Verleye, Nelle Stocquart, Elisabeth Marynen, Frank Hulstaert
Article
Dermatology
D. Beeckman, A. Fourie, C. Raepsaet, N. Van Damme, B. Manderlier, D. De Meyer, H. Beele, S. Smet, L. Demarre, R. Vossaert, A. de Graaf, L. Verhaeghe, N. Vandergheynst, B. Hendrickx, V. Hanssens, H. Keymeulen, K. Vanderwee, J. Van De Woestijne, S. Verhaeghe, A. Van Hecke, I. Savoye, J. Harrison, F. Vrijens, F. Hulstaert
Summary: The study demonstrates that silicone foam dressings can effectively reduce the incidence of category 2 or worse PUs in hospitalized at-risk patients, especially for sacral areas. No statistical difference was found for the heel and trochanter areas.
BRITISH JOURNAL OF DERMATOLOGY
(2021)
Article
Economics
France Vrijens, Carine Van de Voorde, Maria-Isabel Farfan-Portet, Robert Vander Stichele
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2012)
Article
Oncology
Diego de Miguel-Perez, Edward M. Pickering, Umberto Malapelle, William Grier, Francesco Pepe, Pasquale Pisapia, Gianluca Russo, Joseph A. Pinto, Alessandro Russo, Giancarlo Troncone, Melissa J. Culligan, Katherine A. Scilla, Ranee Mehra, Pranshu Mohindra, Oscar Arrieta, Andres F. Cardona, Marzia Del Re, Ashutosh Sachdeva, Fred R. Hirsch, Andrea Wolf, Joseph S. Friedberg, Christian Rolfo
Summary: In this study, genetic alterations in resectable pleural mesothelioma tissues and blood samples were analyzed, and it was found that high tissue tumor mutational burden, tissue median minor allele frequency, blood tumor mutational burden, and specific mutations were correlated with outcomes in patients with resected PM. These findings suggest that molecular profiling could help identify longer survivors in patients with resected PM.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Davide Melisi, Camilla Zecchetto, Valeria Merz, Giuseppe Malleo, Luca Landoni, Alberto Quinzii, Simona Casalino, Federica Fazzini, Marina Gaule, Camilla Pesoni, Luca Casetti, Alessandro Esposito, Giovanni Marchegiani, Cristiana Piazzola, Mirko D'Onofrio, Riccardo de Robertis, Armando Gabbrielli, Laura Bernardoni, Stefano F. Crino, Silvia Pietrobono, Claudio Luchini, Camillo Aliberti, Guido Martignoni, Stefano Milleri, Giovanni Butturini, Aldo Scarpa, Roberto Salvia, Claudio Bassi
Summary: This study evaluated the safety and activity of liposomal irinotecan in the perioperative treatment of resectable pancreatic ductal adenocarcinoma (rPDAC) patients. The results showed that NALIRIFOX has manageable and active outcomes, and should be further investigated in randomized trials comparing it to standard upfront surgery followed by adjuvant therapy.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Eric Jonasch, Todd M. Bauer, Kyriakos P. Papadopoulos, Elizabeth R. Plimack, Jaime R. Merchan, David F. Mcdermott, M. Dror Michaelson, Leonard J. Appleman, Ananya Roy, Rodolfo F. Perini, Yanfang Liu, Toni K. Choueiri
Summary: After a median follow-up of 41.2 months, belzutifan monotherapy demonstrated durable antitumor activity in patients with advanced ccRCC and acceptable safety.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Patricia A. H. Hamers, Geraldine R. Vink, Marloes A. G. Elferink, Leon M. G. Moons, Cornelis J. A. Punt, Anne M. May, Miriam Koopman
Summary: Screen-detection of the primary tumor is associated with longer overall survival after metachronous metastasis.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Camilla Nero, Nicolo Bizzarri, Stefano Di Berardino, Francesca Sillano, Giuseppe Vizzielli, Francesco Cosentino, Virginia Vargiu, Pierandrea De Iaco, Anna Myriam Perrone, Enrico Vizza, Benito Chiofalo, Stefano Uccella, Fabio Ghezzi, Luigi Carlo Turco, Giacomo Corrado, Diana Giannarelli, Tina Pasciuto, Gian Franco Zannoni, Anna Fagotti, Giovanni Scambia
Summary: This study evaluates the sensitivity and specificity of sentinel-lymph-node mapping compared to systematic lymphadenectomy in detecting lymph node metastasis in early stage ovarian cancer. The results show that sentinel-lymph-node mapping did not reach the expected sensitivity, but ultra-staging protocol improved the accuracy of diagnosis for patients.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Adriana Hepner, Judith M. Versluis, Roslyn Wallace, Clara Allayous, Lauren Julia Brown, Claudia Trojanielloh, Camille Lea Gerardi, Yanina J. L. Jansenj, Prachi Bhave, Bart Neyns, Andrew Haydon, Olivier Michielin, Joanna Manganan Oliver Klein, Alexander N. Shoushtari, Allison Betof Warner, Paolo Antonio Ascierto, Jennifer Leigh McQuade, Matteo S. Carlino, Lisa Zimmer, Celeste Lebbe, Douglas B. Johnson, Shahneen Sandhu, Victoria Atkinson, Christian U. Blank, Serigne N. Lo, Georgina V. Long, Alexander M. Menzies
Summary: Acquired resistance to PD-1 therapy in melanoma is mainly oligometastatic, and patients may have a favorable survival outcome following salvage treatment.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Savannah Roy, Stephanie Lakritz, Anna R. Schreiber, Elizabeth Molina Kuna, Cathy J. Bradley, Lavanya Kondapalli, Jennifer R. Diamond
Summary: This study evaluates major adverse cardiovascular events (MACE) in older women with TNBC treated with anthracycline and taxane-based chemotherapy (ATAX) compared to taxane-based chemotherapy (TAX). The results show that ATAX does not increase the risk of MACE and there is no difference in survival between patients who received TAX and ATAX.
EUROPEAN JOURNAL OF CANCER
(2024)
Letter
Oncology
Pei-Chun Weng, Yau-Li Huang, Chun-Yu Cheng
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Philipp Jansen, Jean Le 'Clerc Arrastia, Daniel Otero Baguer, Maximilian Schmidt, Jennifer Landsberg, Joerg Wenzel, Michael Emberger, Dirk Schadendorf, Eva Hadaschik, Peter Maass, Klaus Georg Griewank
Summary: This study highlights the enormous potential of artificial intelligence in pathology, showing that it can aid in the identification of rare cutaneous adnexal tumors and potentially become a standard tool in routine diagnostics.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Casper W. F. van Eijck, Gaby Strijk, Eveline E. Vietscha, Fleur van der Sijde, Maaike Verheij, Dana A. M. Mustafa, Madelief Vinkc, Joachim G. J. V. Aerts, Casper H. J. van Eijck, Marcella Willemsen
Summary: The study reveals that FOLFIRINOX has immunomodulatory effects, suggesting its potential in immune-based combination therapies for pancreatic cancer. Additionally, certain plasma proteins hold promise as circulating predictive biomarkers for early prediction of FOLFIRINOX response in patients with pancreatic cancer.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Marwan Fakih, Chongkai Wang, Jaideep Sandhu, Jian Ye, Colt Egelston, Xiaochen Li
Summary: This study explores the impact of metastatic sites on treatment outcomes for chemotherapy-refractory colorectal cancer patients. It found that patients with liver or peritoneal metastases had poor treatment outcomes, while those with lung-only metastases showed significant response. The presence of concurrent lymph node or other extrahepatic metastatic disease diminished treatment response in patients with lung metastases. Future checkpoint inhibitor trials should stratify patients based on metastatic locations.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Georgios Christos Tsiatsianis, Candace S. Y. Chan, Ioannis Mouratidis, Nikol Chantzi, Anna Maria Tsiatsiani, Nelson S. Yee, Apostolos Zaravinos, Verena Kantere, Ilias Georgakopoulos-Soares
Summary: The study reveals that nullpeptides can serve as biomarkers for cancer detection and treatment, particularly in highly recurrent cancer patients. These nullpeptides primarily occur in highly expressed genes, particularly in specific loci of oncogenes and tumor suppressors. Recurrent nullpeptides are more likely to be found in neoantigens, which play a significant role in immunotherapy.
EUROPEAN JOURNAL OF CANCER
(2024)
