Article
Oncology
Tsuyoshi Etoh, Masaki Fujiwara, Yuto Yamada, Riho Wada, Yuji Higuchi, Shinichiro Inoue, Masafumi Kodama, Takanori Matsushita, Yusaku Yoshimura, Shigeo Horii, Maiko Fujimori, Kyoko Kakeda, Taichi Shimazu, Naoki Nakaya, Masahiro Tabata, Yosuke Uchitomi, Norihito Yamada, Masatoshi Inagaki
Summary: This study identified a wide range of issues in cancer care for people with mental disorders, from patient factors to public policy level, and highlighted the need for a multidisciplinary approach involving both cancer and psychiatric care professionals to address the disparities.
Article
Oncology
Atlal Abusanad, Assia Bensalem, Emad Shash, Layth Mula-Hussain, Zineb Benbrahim, Sami Khatib, Nafisa Abdelhafiz, Jawaher Ansari, Hoda Jradi, Khaled Alkattan, Abdul R. Jazieh
Summary: This study investigated the prevalence and factors affecting burnout among oncology professionals in the Middle East and North Africa (MENA). The study found that 68% of oncology professionals experienced burnout, with factors such as age, administrative work percentage, and thoughts of quitting oncology being significantly associated with burnout. Additionally, having a hobby, enjoying communication in oncology, and appreciating work-life balance in oncology were associated with lower burnout scores and prevalence.
Article
Public, Environmental & Occupational Health
Marija Andrijic, Darija Kisic Tepavcevic, Marina Nikitovic, Nebojsa Miletic, Tatjana Pekmezovic
Summary: This study aimed to investigate burnout levels among healthcare professionals at a national institution, particularly in oncology. The findings indicated a high prevalence of burnout, especially among nurses and technicians. Factors such as profession, work experience, depression, and quality of life were associated with an increased risk of burnout.
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
(2021)
Review
Oncology
Leeat Granek, Ora Nakash
Summary: This paper reviews the literature on the mental health of oncology healthcare professionals (HCP) before and during the COVID-19 pandemic. The implications of these mental health variables on the personal lives of HCPs, the healthcare system, and patient care are discussed. By summarizing and comparing the data, the paper provides insights into the impact of COVID-19 on the overall mental health of HCPs working in oncology and offers recommendations to improve their lives.
Article
Psychology, Multidisciplinary
Anna Server, Carlos Suso-Ribera, Marcos Perez-Carrasco, Javier Medel, Angela Mesas, Alfonso Ayora, Rosa Maria Gracia
Summary: The 8-week mindfulness program demonstrated feasibility and potential effectiveness in reducing burnout levels among staff in a pain clinic, with high participation rate, excellent adherence, and good acceptability of the program.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Oncology
Chandrika Gibson, Moira O'Connor, Rohen White, Siddhartha Baxi, Georgia Halkett
Summary: This qualitative study aimed to explore the experiences of health professionals working with head and neck cancer patients, focusing on work-life balance, mental health, and wellbeing. It identified challenges such as time and resource constraints, work-life imbalance, patients with complex needs, and lack of self-care in their work. It is crucial to develop interventions to reduce burnout risk and improve retention and capacity of these highly skilled professionals.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2021)
Article
Medicine, General & Internal
Amir Hassine, Guillemette Antoni, Muriel Fender, Katia Slama, Francois-Xavier Leandri, Jean-Luc Fanon, Christelle Auvray, Marie Christine Jaffar Bandjee, Nicolas Traversier, Laurence Fagour, Lise Rochaix, Camilla Fiorina, Dolores Pourette, Eric Opigez, Alexandre Dumont, Marc Bardou
Summary: This study aims to demonstrate that using incentives can improve screening rates for cervical cancer among underserved women in economically deprived areas.
Article
Medicine, General & Internal
Sharnel Miriam Perera, Clare O'Callaghan, Anna Ugalde, Olinda Santin, Cassandra Beer, G. Prue, Katherine Lane, Gerard G. Hanna, Penelope Schofield
Summary: The research gathered perspectives from rural and urban carers as well as healthcare professionals through focus groups and interviews. Findings showed that carers often felt ill-prepared for their caregiving responsibilities and experienced dissatisfaction with the healthcare system. The study highlighted the necessity for a user-friendly, carer-specific website tailored to the Australian context.
Article
Psychology, Multidisciplinary
Pablo Ruisoto, Marina R. Ramirez, Pedro A. Garcia, Belen Paladines-Costa, Silvia L. Vaca, Vicente J. Clemente-Suarez
Summary: Burnout is prevalent among healthcare professionals, and social support mediates the negative effects of burnout on health regardless of gender. The study provides insights for designing effective burnout interventions for healthcare professionals in Ecuador.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychology, Multidisciplinary
Gian Piero Turchi, Ilaria Salvalaggio, Claudio Croce, Marta Silvia Dalla Riva, Luisa Orru, Antonio Iudici
Summary: Through analyzing scientific literature on the health of oncological patients, it is important to consider the overall dimension of individuals' health. This paper presents the results of an Italian study that focuses on the health of healthcare professionals who take care of patients with a neoplasia diagnosis. The findings highlight the impact of healthcare professionals' health on the patients they care for.
BEHAVIORAL SCIENCES
(2022)
Article
Oncology
S. Banerjee, K. H. J. Lim, K. Murali, K. Kamposioras, K. Punie, C. Oing, M. O'Connor, E. Thorne, B. Devnani, M. Lambertini, C. B. Westphalen, P. Garrido, T. Amaral, G. Morgan, J. B. A. G. Haanen, C. Hardy
Summary: The study showed that the COVID-19 pandemic has negatively impacted the well-being and job performance of oncology professionals, with rates of burnout and poor well-being increasing over time. While job performance improved, urgent measures are needed to address well-being and improve resilience.
Article
Multidisciplinary Sciences
Nina Oginska-Bulik, Piotr Jerzy Gurowiec, Paulina Michalska, Edyta Kedra
Summary: The study showed that job satisfaction is the main predictor of STS symptoms in medical personnel. In addition, two cognitive strategies - regret (positive relation) and resolution/acceptance (negative relation) - are also predictors of STS. Other analyzed variables, such as denial, workload and social support, have a relatively small contribution to explaining the dependent variable.
Article
Public, Environmental & Occupational Health
Yared Mulu Gelaw, Kashtan Hanoch, Bruria Adini
Summary: This study found that a substantial number of healthcare professionals in surgical and obstetric departments in Ethiopian hospitals experience burnout, with high emotional exhaustion, depersonalization, and low personal accomplishment. Factors such as profession, professional recognition, and workload were found to predict burnout. The study also revealed a negative association between resilience at work and emotional exhaustion and depersonalization, and a positive association between resilience at work and personal accomplishment. Therefore, efforts should be made to enhance healthcare professionals' resilience at work and reduce job burnout.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Oncology
K. H. J. Lim, K. Murali, K. Kamposioras, K. Punie, C. Oing, M. O'Connor, E. Thorne, T. Amaral, P. Garrido, M. Lambertini, B. Devnani, C. B. Westphalen, G. Morgan, J. B. A. G. Haanen, C. Hardy, S. Banerjee
Summary: The COVID-19 pandemic has significantly impacted the professional and personal lives of oncology professionals globally, leading to increased distress, burnout, and concerns about career development and job security. Efforts to address mental health support and coping strategies are crucial for recovery from the crisis.
Review
Psychiatry
Juliana Pontes Soares, Rayssa Horacio Lopes, Paula Beatriz de Souza Mendonca, Cicera Renata Diniz Vieira Silva, Claudia Cristiane Filgueira Martins Rodrigues, Janete Lima de Castro
Summary: This study aims to identify and determine burnout syndrome among health professionals working in public health services using the Maslach Burnout Inventory (MBI) scale. The study found that burnout syndrome is prevalent among health professionals and is associated with long working hours and lack of proper rest.
JMIR MENTAL HEALTH
(2023)
Article
Ethnic Studies
Patsy S. Soon, Neda Karimi, Verena S. Wu, Afaf Girgis
Summary: This study explored the factors influencing Vietnamese- and English-speaking women's decisions about breast reconstruction after mastectomy for breast cancer treatment. The results revealed that lack of information was a persistent barrier, with Vietnamese women identifying this issue more significantly. The importance of doctors' recommendations in helping Vietnamese women make informed decisions about reconstruction was emphasized.
ETHNICITY & HEALTH
(2022)
Review
Oncology
Verena Shuwen Wu, Allan Ben Smith, Afaf Girgis
Summary: This systematic review aims to identify the unmet supportive care needs of immigrant and native Chinese cancer patients and caregivers. The most prevalent area of unmet needs was health system and information, with patients desiring one member of the hospital to talk to about all aspects of their care and caregivers seeking information about the patient's prognosis and likely outcome.
EUROPEAN JOURNAL OF CANCER CARE
(2022)
Article
Health Care Sciences & Services
Andrew H. Kim, Afaf Girgis, Peter De Cruz, Corey A. Siegel, Neda Karimi, Sasha O. Ruban, Alexandra J. Sechi, Wa Sang Watson Ng, Jane M. Andrews, Susan J. Connor
Summary: This study aims to explore the feasibility and acceptability of myAID, a web-based decision aid, in informing treatment decisions for ulcerative colitis (UC) from the perspectives of Australian patients and clinicians. The study found that myAID was generally acceptable to clinicians as a tool to facilitate shared decision making (SDM) in UC management, but its uptake varied depending on clinicians' approaches to patient education and practice.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Medicine, General & Internal
Reema Harrison, Merrilyn Walton, Elizabeth Manias, Carlene Wilson, Afaf Girgis, Melvin Chin, Desiree Leone, Holly Seale, Allan Ben Smith, Ashfaq Chauhan
Summary: Consumer engagement is crucial for high-quality cancer service delivery and reducing healthcare-associated harm. This project aims to use an adapted approach to experience-based codesign (EBCD) to codesign consumer engagement interventions tailored for ethnic minority populations, in order to increase consumer engagement and safety in cancer services in New South Wales and Victoria.
Article
Education & Educational Research
Emma R. Pollock, Myles D. Young, David R. Lubans, Julia E. Coffey, Vibeke Hansen, Philip J. Morgan
Summary: The study found that a university teacher education course had a positive impact on preservice and inservice teachers' attitudes towards gender equity, with preservice teachers reducing negative attitudes towards girls and activity, and both preservice and inservice teachers improving awareness and skills to address gender-related issues in schools. Targeted teacher education courses have the potential to improve gender equity in schools.
TEACHING AND TEACHER EDUCATION
(2021)
Article
Psychology, Social
Janelle Levesque, Adeola Bamgboje-Ayodele, Jessica Paradiso, Joseph Descallar, Afaf Girgis
Summary: The study found that self-efficacy is significantly negatively related to emotional distress, challenges experienced, and unmet needs among male caregivers of women with breast cancer. The mediation model accounted for a significant 18% of emotional distress variability, but self-efficacy did not mediate the relationship between challenges and emotional distress or between unmet needs and emotional distress.
JOURNAL OF PSYCHOSOCIAL ONCOLOGY
(2022)
Article
Health Care Sciences & Services
Tegan Bradley, Vibeke Hansen, Paula Wye, Elizabeth Campbell, Kate Bartlem, Kate Reid, Jenny Bowman
Summary: People with mental health conditions have a higher prevalence of chronic diseases and shorter life expectancy than the general population. Health risk behaviors, such as physical inactivity and poor nutrition, contribute to these disparities. Population-level health coaching delivered via telephone can be a valuable tool to support behavior change in this high-risk group. Coaches play a crucial role in building confidence and readiness to change, with a focus on improving both physical and mental health outcomes for participants. Training and support for coaches, along with potential adjustments to service delivery, could enhance engagement and outcomes for individuals with mental health conditions. Further research on the experiences of mental health consumers engaging with telephone coaching services is warranted.
BMC HEALTH SERVICES RESEARCH
(2021)
Article
Oncology
Verena Shuwen Wu, Allan 'Ben' Smith, Afaf Girgis
Summary: This study developed a self-management intervention, WeCope, to support Chinese immigrant patients affected by cancer and their caregivers through a community participatory approach. Participants expressed overall satisfaction with the resource and provided suggestions for improvement, particularly in providing more information on treatment-related issues and support services.
EUROPEAN JOURNAL OF CANCER CARE
(2022)
Article
Medicine, General & Internal
Patricia M. Livingston, Lahiru Russell, Liliana Orellana, Natalie Winter, Michael Jefford, Afaf Girgis, David Austin, O. Eric, Cathrine Mihalopoulos, Anna Ugalde, Richard Chambers, Jo Phipps-Nelson, Dishan Herath, Mari Botti, Bodil Rasmussen, Kathryn Whitfield, Maria Ftanou, Allan Ben Smith, Kirsten Pilatti, Sally Sara, Addie Wootten, Kate Gillan, Madhu Singh, David Campbell, Brindha Pillay, Victoria White
Summary: Fear of cancer recurrence (FCR) is a common psychological issue among cancer survivors, causing distress and anxiety. Online mindfulness programmes, such as MindOnLine, may help cancer survivors manage FCR and improve their well-being. This study aims to determine the potential efficacy of MindOnLine for survivors of breast, prostate, and colorectal cancer through a single-blind randomized controlled trial. The findings of this study will be disseminated in peer-reviewed journals and among key stakeholders.
Article
Environmental Sciences
Ryan J. Drew, Philip J. Morgan, Frances Kay-Lambkin, Clare E. Collins, Robin Callister, Brian J. Kelly, Vibeke Hansen, Myles D. Young
Summary: The study found that gender-tailored, self-directed lifestyle interventions incorporating mental health support are acceptable and satisfying for men experiencing depressive symptoms, helping them improve their physical and mental health conditions.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Anna K. Jansson, David R. Lubans, Jordan J. Smith, Mitch J. Duncan, Vibeke Hansen, Ronald C. Plotnikoff
Summary: This study explores the impact of the COVID-19 pandemic on participant experience and motivation in the ecofit program. The findings suggest that overall physical activity levels increased during the pandemic, although the impact on the ecofit intervention is yet to be determined.
JOURNAL OF PHYSICAL ACTIVITY & HEALTH
(2022)
Article
Education & Educational Research
Stina Oftedal, Sasha Fenton, Vibeke Hansen, Megan C. C. Whatnall, Lee M. Ashton, Rebecca L. L. Haslam, Melinda J. J. Hutchesson, Mitch J. J. Duncan
Summary: This study aimed to explore the impact of starting university on young adults' physical activity, diet, sleep, and mental well-being, as well as the barriers and enablers to health behavior change. The findings revealed that mental well-being, physical activity levels, diet quality, and sleep health were negatively affected among university students. Key barriers included stress, study demands, university timetabling, lack of prioritization of physical activity, cost and availability of healthy foods, and difficulty falling asleep. Future interventions should focus on providing both information and support to improve mental well-being. Conclusion: There is a significant opportunity to enhance the transition to university for young adults, targeting areas such as physical activity, diet, and sleep.
JOURNAL OF AMERICAN COLLEGE HEALTH
(2023)
Article
Health Care Sciences & Services
Afaf Girgis, Adeola Bamgboje-Ayodele, Orlando Rincones, Shalini K. Vinod, Sandra Avery, Joseph Descallar, Allan 'Ben' Smith, Belinda Arnold, Anthony Arnold, Victoria Bray, Ivana Durcinoska, Nicole M. Rankin, PROMPT-Care Implementation Authorship Group, Geoff P. Delaney
Summary: This study implemented an effective ePROM system (PRM system) for lung cancer patients in routine care, using the RE-AIM framework. The study showed that the implementation of the PRM system successfully improved the routine care of lung cancer patients by identifying patient concerns early and providing timely responses, resulting in fewer visits to the cancer assessment unit and increased confidence and engagement of healthcare providers.
JOURNAL OF PATIENT-REPORTED OUTCOMES
(2022)
Article
Environmental Sciences
Vibeke Hansen, Sabrina Winona Pit, Michele Fiorentino, Selina Campion, Ryan Abraham, Jonathan Cheng, Sue Phelan
Summary: This study found that transitions in antidepressant medication have significant impacts on employment and workplace functioning, with participants reporting both positive effects of the medication and negative effects during transitions. Practical solutions were suggested to help employers, policymakers, and clinicians support individuals during these transition events.
ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Belinda L. Arnold, Georgia Halkett, Haryana Dhillon, Afaf Girgis
Summary: The majority of radiation therapists lack training in psychosocial and emotional cues, some believe discussing patients' psychosocial concerns is part of their role but still feel insufficient knowledge and confidence to conduct symptom and distress screening.
JOURNAL OF MEDICAL RADIATION SCIENCES
(2021)
Article
Oncology
Diego de Miguel-Perez, Edward M. Pickering, Umberto Malapelle, William Grier, Francesco Pepe, Pasquale Pisapia, Gianluca Russo, Joseph A. Pinto, Alessandro Russo, Giancarlo Troncone, Melissa J. Culligan, Katherine A. Scilla, Ranee Mehra, Pranshu Mohindra, Oscar Arrieta, Andres F. Cardona, Marzia Del Re, Ashutosh Sachdeva, Fred R. Hirsch, Andrea Wolf, Joseph S. Friedberg, Christian Rolfo
Summary: In this study, genetic alterations in resectable pleural mesothelioma tissues and blood samples were analyzed, and it was found that high tissue tumor mutational burden, tissue median minor allele frequency, blood tumor mutational burden, and specific mutations were correlated with outcomes in patients with resected PM. These findings suggest that molecular profiling could help identify longer survivors in patients with resected PM.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Davide Melisi, Camilla Zecchetto, Valeria Merz, Giuseppe Malleo, Luca Landoni, Alberto Quinzii, Simona Casalino, Federica Fazzini, Marina Gaule, Camilla Pesoni, Luca Casetti, Alessandro Esposito, Giovanni Marchegiani, Cristiana Piazzola, Mirko D'Onofrio, Riccardo de Robertis, Armando Gabbrielli, Laura Bernardoni, Stefano F. Crino, Silvia Pietrobono, Claudio Luchini, Camillo Aliberti, Guido Martignoni, Stefano Milleri, Giovanni Butturini, Aldo Scarpa, Roberto Salvia, Claudio Bassi
Summary: This study evaluated the safety and activity of liposomal irinotecan in the perioperative treatment of resectable pancreatic ductal adenocarcinoma (rPDAC) patients. The results showed that NALIRIFOX has manageable and active outcomes, and should be further investigated in randomized trials comparing it to standard upfront surgery followed by adjuvant therapy.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Eric Jonasch, Todd M. Bauer, Kyriakos P. Papadopoulos, Elizabeth R. Plimack, Jaime R. Merchan, David F. Mcdermott, M. Dror Michaelson, Leonard J. Appleman, Ananya Roy, Rodolfo F. Perini, Yanfang Liu, Toni K. Choueiri
Summary: After a median follow-up of 41.2 months, belzutifan monotherapy demonstrated durable antitumor activity in patients with advanced ccRCC and acceptable safety.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Patricia A. H. Hamers, Geraldine R. Vink, Marloes A. G. Elferink, Leon M. G. Moons, Cornelis J. A. Punt, Anne M. May, Miriam Koopman
Summary: Screen-detection of the primary tumor is associated with longer overall survival after metachronous metastasis.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Camilla Nero, Nicolo Bizzarri, Stefano Di Berardino, Francesca Sillano, Giuseppe Vizzielli, Francesco Cosentino, Virginia Vargiu, Pierandrea De Iaco, Anna Myriam Perrone, Enrico Vizza, Benito Chiofalo, Stefano Uccella, Fabio Ghezzi, Luigi Carlo Turco, Giacomo Corrado, Diana Giannarelli, Tina Pasciuto, Gian Franco Zannoni, Anna Fagotti, Giovanni Scambia
Summary: This study evaluates the sensitivity and specificity of sentinel-lymph-node mapping compared to systematic lymphadenectomy in detecting lymph node metastasis in early stage ovarian cancer. The results show that sentinel-lymph-node mapping did not reach the expected sensitivity, but ultra-staging protocol improved the accuracy of diagnosis for patients.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Adriana Hepner, Judith M. Versluis, Roslyn Wallace, Clara Allayous, Lauren Julia Brown, Claudia Trojanielloh, Camille Lea Gerardi, Yanina J. L. Jansenj, Prachi Bhave, Bart Neyns, Andrew Haydon, Olivier Michielin, Joanna Manganan Oliver Klein, Alexander N. Shoushtari, Allison Betof Warner, Paolo Antonio Ascierto, Jennifer Leigh McQuade, Matteo S. Carlino, Lisa Zimmer, Celeste Lebbe, Douglas B. Johnson, Shahneen Sandhu, Victoria Atkinson, Christian U. Blank, Serigne N. Lo, Georgina V. Long, Alexander M. Menzies
Summary: Acquired resistance to PD-1 therapy in melanoma is mainly oligometastatic, and patients may have a favorable survival outcome following salvage treatment.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Savannah Roy, Stephanie Lakritz, Anna R. Schreiber, Elizabeth Molina Kuna, Cathy J. Bradley, Lavanya Kondapalli, Jennifer R. Diamond
Summary: This study evaluates major adverse cardiovascular events (MACE) in older women with TNBC treated with anthracycline and taxane-based chemotherapy (ATAX) compared to taxane-based chemotherapy (TAX). The results show that ATAX does not increase the risk of MACE and there is no difference in survival between patients who received TAX and ATAX.
EUROPEAN JOURNAL OF CANCER
(2024)
Letter
Oncology
Pei-Chun Weng, Yau-Li Huang, Chun-Yu Cheng
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Philipp Jansen, Jean Le 'Clerc Arrastia, Daniel Otero Baguer, Maximilian Schmidt, Jennifer Landsberg, Joerg Wenzel, Michael Emberger, Dirk Schadendorf, Eva Hadaschik, Peter Maass, Klaus Georg Griewank
Summary: This study highlights the enormous potential of artificial intelligence in pathology, showing that it can aid in the identification of rare cutaneous adnexal tumors and potentially become a standard tool in routine diagnostics.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Casper W. F. van Eijck, Gaby Strijk, Eveline E. Vietscha, Fleur van der Sijde, Maaike Verheij, Dana A. M. Mustafa, Madelief Vinkc, Joachim G. J. V. Aerts, Casper H. J. van Eijck, Marcella Willemsen
Summary: The study reveals that FOLFIRINOX has immunomodulatory effects, suggesting its potential in immune-based combination therapies for pancreatic cancer. Additionally, certain plasma proteins hold promise as circulating predictive biomarkers for early prediction of FOLFIRINOX response in patients with pancreatic cancer.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Marwan Fakih, Chongkai Wang, Jaideep Sandhu, Jian Ye, Colt Egelston, Xiaochen Li
Summary: This study explores the impact of metastatic sites on treatment outcomes for chemotherapy-refractory colorectal cancer patients. It found that patients with liver or peritoneal metastases had poor treatment outcomes, while those with lung-only metastases showed significant response. The presence of concurrent lymph node or other extrahepatic metastatic disease diminished treatment response in patients with lung metastases. Future checkpoint inhibitor trials should stratify patients based on metastatic locations.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Georgios Christos Tsiatsianis, Candace S. Y. Chan, Ioannis Mouratidis, Nikol Chantzi, Anna Maria Tsiatsiani, Nelson S. Yee, Apostolos Zaravinos, Verena Kantere, Ilias Georgakopoulos-Soares
Summary: The study reveals that nullpeptides can serve as biomarkers for cancer detection and treatment, particularly in highly recurrent cancer patients. These nullpeptides primarily occur in highly expressed genes, particularly in specific loci of oncogenes and tumor suppressors. Recurrent nullpeptides are more likely to be found in neoantigens, which play a significant role in immunotherapy.
EUROPEAN JOURNAL OF CANCER
(2024)
