Article
Chemistry, Multidisciplinary
Fabiola Spolaor, Annamaria Guiotto, Alfredo Ciniglio, Zimi Sawacha
Summary: Foot ulcers are a serious complication of diabetes, and it is recommended for diabetic individuals to wear appropriate footwear or insoles to reduce pressure. This study investigated the effects of custom insoles on biomechanical and neuromuscular functions in diabetic neuropathic individuals. The results showed that custom insoles reduced plantar pressure through surface redistribution and decreased electromyographic activity.
APPLIED SCIENCES-BASEL
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xin Wang, Lei Luo, Jianming Xing, Jianliang Wang, Bimin Shi, Yin-Min Li, Yong-Gang Li
Summary: The study demonstrated that DTI is effective in evaluating the diagnostic accuracy of diabetic peripheral neuropathy and can effectively differentiate between axonal injury and demyelination, showing correlations with electrophysiology parameters.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Article
Neurosciences
B. A. Petersen, P. J. Sparto, L. E. Fisher
Summary: The study aims to determine the relationship between sensory impairments and clinical functional measures of balance and gait in individuals with a lower-limb amputation. The findings suggest that sensory impairments do not significantly affect functional measures in this population.
Article
Computer Science, Interdisciplinary Applications
Weronika Piatkowska, Fabiola Spolaor, Annamaria Guiotto, Gabriella Guarneri, Angelo Avogaro, Zimi Sawacha
Summary: The aim of this study was to determine the most suitable sEMG parameters for classifying diabetic patients with and without neuropathy and distinguishing them from healthy controls, as well as to assess the role of the task in the classification process. By conducting tests on 30 subjects and recording the electrical activity of six muscles, the study found that applying a hierarchical clustering algorithm can successfully classify the subjects into different groups.
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
(2022)
Article
Endocrinology & Metabolism
Lining Dong, Yanyun Hu, Lei Xu, Hui Zeng, Wenqi Shen, Patrick Esser, Helen Dawes, Fang Liu
Summary: It is believed that gait characteristics differ between diabetic neuropathic patients and non-diabetic individuals. However, the influence of abnormal foot sensation on gait during walking in type 2 diabetes is still unclear. In this study, gait features were compared among participants with normal glucose tolerance and diabetic individuals with or without peripheral neuropathy, in order to gain insight into the alterations of detailed gait parameters and identify important aspects in gait indexes affected by peripheral neuropathy in older type 2 diabetes patients.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Jaewook Kim, Yekwang Kim, Seung-Jong Kim
Summary: Current gait rehabilitation strategies heavily rely on motor learning principles, but the use of exoskeleton-type robots may deviate the gait patterns from natural gait, especially during the weight acceptance stage.
APPLIED SCIENCES-BASEL
(2022)
Article
Neurosciences
Kyeongjin Lee
Summary: This study suggests that EMG-triggered pedaling training effectively improves lower extremity motor function, muscle activation, gait, postural balance, and activities of daily living in stroke patients.
Review
Engineering, Biomedical
Michael Gonzalez, Alex Bismuth, Christina Lee, Cynthia A. Chestek, Deanna H. Gates
Summary: This systematic review explored the parameters, qualities, and assessment methods of referred sensation induced by electrical stimulation in individuals with limb loss. The most commonly adjusted parameter was amplitude, and pressure, paresthesia, and vibration were the most reported qualities. Most studies evaluated the functional benefits of sensation, while fewer studies quantified subjective measures. Direct comparisons between studies were limited by variability in methodologies and outcome measures.
JOURNAL OF NEURAL ENGINEERING
(2022)
Article
Physiology
AmirAli Jafarnezhadgero, Elahe Mamashli, Urs Granacher
Summary: The study demonstrated that an endurance-dominated exercise program can improve VO(2)max and diabetes-related abnormal gait in patients with DN. The decreases in peak vertical ground reaction force during heel contact of walking may be due to increased activities of vastus lateralis and gluteus medius during the loading phase. Therefore, implementing endurance-dominated exercise programs in type 2 diabetic patients is recommended as it is feasible, safe, and effective in improving aerobic capacity and gait characteristics.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Business
Sharon A. Simmons, Jon C. Carr, Dan Hsu, S. Bartholomew Craig
Summary: This study examines the impact of prior success or failure feedback on individuals' motivation to reengage in entrepreneurship and explores the moderating effects of sensation-seeking and workaholism. The results demonstrate that entrepreneurs' compulsive traits can mitigate the cognitive influence of prior performance feedback on their decision to reengage in entrepreneurship.
JOURNAL OF BUSINESS RESEARCH
(2023)
Article
Nutrition & Dietetics
Dimitris Efthymiou, Niki Katsiki, Dimitrios Xipolias Zekakos, Panagiotis Vassiliadis, Alexandros Petrelis, Emilia Vassilopoulou
Summary: The study aimed to assess the early gait changes in T2DM patients without clinical signs of DPN compared to healthy controls. Significant differences were found in some gait parameters between the T2DM group and the control group. Further research is needed to explore whether gait analysis can be used as an early diagnostic tool for T2DM complications.
Article
Endocrinology & Metabolism
Tian Tian, Cheng Wang, Yuan Xu, Yuzhi Bai, Jing Wang, Zhou Long, Xiangdong Wang, Lichun Zhou
Summary: This study utilized a wearable gait analysis system to investigate the gait of patients with type 2 diabetes mellitus, revealing significant differences in certain gait parameters compared to the healthy control group. The landing angle and maximum swing angle of diabetes patients, as well as the walking speed of patients with peripheral neuropathy, were found to be significantly lower than controls. This confirms the potential of the wearable gait analysis system in identifying abnormal gait patterns in diabetic patients and providing new insights for diabetes-related gait research.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY
(2021)
Article
Neurosciences
Alec T. Beeve, Ivana Shen, Xiao Zhang, Kristann Magee, Ying Yan, Matthew R. MacEwan, Erica L. Scheller
Summary: Bioelectric nerve stimulation (eStim) is a potential strategy to promote neural and musculoskeletal health in diabetes, but its ability to prevent diabetic nerve and musculoskeletal complications remains unclear. This study found that while eStim did not prevent diabetes-induced neuroskeletal complications, it highlights the importance of considering device placement and long-term skeletal health in both healthy individuals and those with metabolic disease.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Neurosciences
Gena Henderson, Diego Ferreira, Jianhua Wu
Summary: The study found that typically developing children adapt their gait to changes in direction and speed of treadmill walking in ways similar to adults, but with notable differences in ankle range of motion.
Article
Biophysics
Amanda E. Munsch, Brian Pietrosimone, Jason R. Franz
Summary: This study aimed to investigate the net fascicle length change of the quadriceps muscles at different walking speeds. The results showed that the VL muscle accommodates greater mechanical demands at faster speeds with increased muscle activity, while also resisting muscle lengthening. These findings are important for further evaluating VL fascicle behavior in individuals with known quadriceps strength deficits, inhibition, or heightened risk.
JOURNAL OF BIOMECHANICS
(2022)