Combination pharmacotherapy to prevent cardiovascular disease: present status and challenges

Rationale and design of the Kanyini guidelines adherence with the polypill (Kanyini-GAP) study: a randomised controlled trial of a polypill-based strategy amongst Indigenous and non Indigenous people at high cardiovascular risk

(2016) Hueiming Liu et al.   BMC PUBLIC HEALTH

Why are we failing to implement effective therapies in cardiovascular disease?

(2013) Robby Nieuwlaat et al.   EUROPEAN HEART JOURNAL

Effects of a Fixed-Dose Combination Strategy on Adherence and Risk Factors in Patients With or at High Risk of CVD

(2013) Simon Thom   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prevalence, Awareness, Treatment, and Control of Hypertension in Rural and Urban Communities in High-, Middle-, and Low-Income Countries

(2013) Clara K. Chow   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The story of artesunate–mefloquine (ASMQ), innovative partnerships in drug development: case study

(2013) Susan Wells et al.   MALARIA JOURNAL

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet

(2013) Ramón Estruch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adherence to Drugs That Prevent Cardiovascular Disease: Meta-analysis on 376,162 Patients

(2012) Sayed H. Naderi et al.   AMERICAN JOURNAL OF MEDICINE

Relationship Between Healthy Diet and Risk of Cardiovascular Disease Among Patients on Drug Therapies for Secondary Prevention

(2012) Mahshid Dehghan et al.   CIRCULATION

Comparison of Risk Factor Reduction and Tolerability of a Full-Dose Polypill (With Potassium) Versus Low-Dose Polypill (Polycap) in Individuals at High Risk of Cardiovascular Diseases

(2012) Salim Yusuf et al.  

European Guidelines on cardiovascular disease prevention in clinical practice (version 2012): The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts) * Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)

(2012) et al.   EUROPEAN HEART JOURNAL

The Rural Andhra Pradesh Cardiovascular Prevention Study (RAPCAPS)

(2012) Rohina Joshi et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Randomized Polypill Crossover Trial in People Aged 50 and Over

(2012) David S. Wald et al.   PLoS One

The Fixed-dose Combination Drug for Secondary Cardiovascular Prevention project: Improving equitable access and adherence to secondary cardiovascular prevention with a fixed-dose combination drug. Study design and objectives

(2011) Ginés Sanz et al.   AMERICAN HEART JOURNAL

Medication adherence: A call for action

(2011) Hayden B. Bosworth et al.   AMERICAN HEART JOURNAL

Potential impact of single-risk-factor versus total risk management for the prevention of cardiovascular events in Seychelles

(2011) Roger Ndindjock et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Value of Primordial and Primary Prevention for Cardiovascular Disease

(2011) William S. Weintraub et al.   CIRCULATION

Dose Response Between Physical Activity and Risk of Coronary Heart Disease

(2011) Jacob Sattelmair et al.   CIRCULATION

Improving adherence using combination therapy (IMPACT): Design and protocol of a randomised controlled trial in primary care

(2011) Vanessa Selak et al.   Contemporary Clinical Trials

AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2011 Update

(2011) Sidney C. Smith et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey

(2011) Salim Yusuf et al.   LANCET

Medication Adherence: WHO Cares?

(2011) Marie T. Brown et al.   MAYO CLINIC PROCEEDINGS

An International Randomised Placebo-Controlled Trial of a Four-Component Combination Pill (“Polypill”) in People with Raised Cardiovascular Risk

(2011)   PLoS One

A Polypill for primary prevention of cardiovascular disease: A feasibility study of the World Health Organization

(2011) Elsayed Z Soliman et al.   Trials

Evaluation of Cardiovascular Morbidity Associated with Adherence to Atorvastatin Therapy

(2010) Dale A Rublee et al.   AMERICAN JOURNAL OF THERAPEUTICS

Estimating modifiable coronary heart disease risk in multiple regions of the world: the INTERHEART Modifiable Risk Score

(2010) C. McGorrian et al.   EUROPEAN HEART JOURNAL

A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy (‘polypill’) on cardiovascular risk factors

(2010) F. Malekzadeh et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

The effects of adherence and persistence on clinical outcomes in patients treated with statins: A systematic review

(2010) Ross J. Simpson et al.   Journal of Clinical Lipidology

Better compliance to antihypertensive medications reduces cardiovascular risk

(2010) Giovanni Corrao et al.   JOURNAL OF HYPERTENSION

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

(2010)   LANCET

Acceptance of a Polypill Approach to Prevent Cardiovascular Disease Among a Sample of U.S. Physicians

(2010) Anthony J. Viera et al.   PREVENTIVE MEDICINE

Continuation of Statin Treatment and All-Cause Mortality

(2009) Varda Shalev et al.   ARCHIVES OF INTERNAL MEDICINE

EUROASPIRE III: a survey on the lifestyle, risk factors and use of cardioprotective drug therapies in coronary patients from 22 European countries

(2009) Kornelia Kotseva et al.   EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION

Effectiveness of Public Report Cards for Improving the Quality of Cardiac Care

(2009) Jack V. Tu et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomised trial

(2009)   LANCET

Barriers to and Determinants of Medication Adherence in Hypertension Management: Perspective of the Cohort Study of Medication Adherence Among Older Adults

(2009) Marie A. Krousel-Wood et al.   MEDICAL CLINICS OF NORTH AMERICA

Barriers to Antihypertensive Medication Adherence Among Adults- United States, 2005

(2008) Lemuel Vawter et al.   Journal of Clinical Hypertension