miRNA-21 is dysregulated in response to vein grafting in multiple models and genetic ablation in mice attenuates neointima formation

miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling

(2012) Shanzhong Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Off-Pump Coronary Artery Bypass Surgery Is Associated With Worse Arterial and Saphenous Vein Graft Patency and Less Effective Revascularization

(2012) Brack Hattler et al.   CIRCULATION

Vein graft failure: current clinical practice and potential for gene therapeutics

(2012) S Wan et al.   GENE THERAPY

Antagonist of microRNA-21 improves balloon injury-induced rat iliac artery remodeling by regulating proliferation and apoptosis of adventitial fibroblasts and myofibroblasts

(2012) Fei Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Comparative Effectiveness of Revascularization Strategies

(2012) William S. Weintraub et al.   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion

(2012) L. Maegdefessel et al.   Science Translational Medicine

MicroRNA-21 Regulates Vascular Smooth Muscle Cell Function via Targeting Tropomyosin 1 in Arteriosclerosis Obliterans of Lower Extremities

(2011) Mian Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

(2011) Emma Raitoharju et al.   ATHEROSCLEROSIS

MicroRNA and vascular remodelling in acute vascular injury and pulmonary vascular remodelling

(2011) R. A. McDonald et al.   CARDIOVASCULAR RESEARCH

Sustained Reduction of Vein Graft Neointima Formation by Ex Vivo TIMP-3 Gene Therapy

(2011) S. J. George et al.   CIRCULATION

MicroRNA-133 Controls Vascular Smooth Muscle Cell Phenotypic Switch In Vitro and Vascular Remodeling In Vivo

(2011) Daniele Torella et al.   CIRCULATION RESEARCH

MicroRNA 21 regulates the proliferation of human adipose tissue-derived mesenchymal stem cells and high-fat diet-induced obesity alters microRNA 21 expression in white adipose tissues

(2011) Yeon Jeong Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

An essential role of PDCD4 in vascular smooth muscle cell apoptosis and proliferation: implications for vascular disease

(2010) Xiaojun Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Modulation of K-Ras-Dependent Lung Tumorigenesis by MicroRNA-21

(2010) Mark E. Hatley et al.   CANCER CELL

Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation

(2010) Seth B. Furgeson et al.   CARDIOVASCULAR RESEARCH

Randomized trial to compare bilateral vs. single internal mammary coronary artery bypass grafting: 1-year results of the Arterial Revascularisation Trial (ART)

(2010) D. P. Taggart et al.   EUROPEAN HEART JOURNAL

Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice

(2010) David M. Patrick et al.   JOURNAL OF CLINICAL INVESTIGATION

The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease

(2009) L Elia et al.   CELL DEATH AND DIFFERENTIATION

MicroRNA-145, a Novel Smooth Muscle Cell Phenotypic Marker and Modulator, Controls Vascular Neointimal Lesion Formation

(2009) Yunhui Cheng et al.   CIRCULATION RESEARCH

MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3

(2009) Florin M. Selaru et al.   HEPATOLOGY

On-Pump versus Off-Pump Coronary-Artery Bypass Surgery

(2009) A. Laurie Shroyer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Percutaneous Coronary Intervention versus Coronary-Artery Bypass Grafting for Severe Coronary Artery Disease

(2009) Patrick W. Serruys et al.   NEW ENGLAND JOURNAL OF MEDICINE