Altered HCN4 channel C-linker interaction is associated with familial tachycardia–bradycardia syndrome and atrial fibrillation

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

(2012) Patrick T Ellinor et al.   NATURE GENETICS

Tetramerization Dynamics of C-terminal Domain Underlies Isoform-specific cAMP Gating in Hyperpolarization-activated Cyclic Nucleotide-gated Channels

(2011) Marco Lolicato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

(2011) M. Baruscotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tachybradycardia in the isolated canine right atrium induced by chronic sympathetic stimulation and pacemaker current inhibition

(2010) Boyoung Joung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Complex Interactions Between the Sinoatrial Node and Atrium During Reentrant Arrhythmias in the Canine Heart

(2010) Vadim V. Fedorov et al.   CIRCULATION

cAMP Sensitivity of HCN Pacemaker Channels Determines Basal Heart Rate But Is Not Critical for Autonomic Rate Control

(2010) Patrick A. Schweizer et al.   Circulation-Arrhythmia and Electrophysiology

Structural Basis for the cAMP-dependent Gating in the Human HCN4 Channel

(2010) Xinping Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Architecture of the Human Sinus Node

(2009) Natalie J. Chandler et al.   CIRCULATION

Funny Current Downregulation and Sinus Node Dysfunction Associated With Atrial Tachyarrhythmia

(2009) Yung-Hsin Yeh et al.   CIRCULATION