Article
Cardiac & Cardiovascular Systems
Po-Cheng Chang, Ming-Shien Wen, Chung-Chuan Chou, Chun-Chieh Wang, Kuo-Chun Hung
Summary: This study demonstrated the feasibility of ambulatory monitoring for atrial fibrillation (AF) detection using a commercial smartwatch in daily life, suggesting that a smartwatch may be an alternative screening tool to standard ambulatory Holter monitoring.
AMERICAN HEART JOURNAL
(2022)
Article
Medicine, General & Internal
Gregory F. Michaud, William G. Stevenson
Summary: A 63-year-old healthy male with atrial fibrillation presents with symptoms of dyspnea and irregular heartbeat. Physical examination reveals high blood pressure, irregular pulse, and ECG confirms atrial fibrillation. Further evaluation and treatment plan are needed.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Letter
Medicine, General & Internal
Isaac W. Leon-acuna, Takeki Suzuki
Summary: Andrade et al. found that initial catheter cryoballoon ablation strategy resulted in lower incidence of persistent atrial fibrillation and lower arrhythmia burden compared to antiarrhythmic drug therapy in patients with paroxysmal atrial fibrillation during 3 years of follow-up. The study builds upon the findings of the EARLY-AF trial and the STOP AF First trial. Due to the relatively small sample size (303 patients) and short follow-up period, it may be difficult to detect mortality benefits of cryoballoon ablation.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Ying Liu, Yi Zheng, Gary Tse, George Bazoukis, Konstantinos Letsas, Christos Goudis, Panagiotis Korantzopoulos, Guangping Li, Tong Liu
Summary: This systematic review and meta-analysis aimed to explore the relationship between sick sinus syndrome (SSS) and atrial fibrillation (AF) and compare different therapy strategies for patients with SSS and AF. Results showed that SSS was associated with a higher risk of new-onset AF. Catheter ablation was found to be more effective than pacemaker therapy in reducing the risk of AF recurrence, AF progression, mortality, stroke, and heart failure hospitalization. Different pacing strategies for SSS were also compared, with VVI/VVIR showing a higher risk of new-onset AF compared to DDD/DDDR. AAI/AAIR had a higher risk of all-cause mortality but a lower risk of cardiac death compared to DDD/DDDR. Right atrial septum pacing showed similar risks of new-onset AF or AF recurrence compared to right atrial appendage pacing. The meta-analysis emphasized the importance of avoiding high ventricular pacing percentages in SSS patients to reduce AF burden and mortality.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Multidisciplinary Sciences
Keita Watanabe, Yasutoshi Nagata, Giichi Nitta, Shinichiro Okata, Masashi Nagase, Ryoichi Miyazaki, Sho Nagamine, Masakazu Kaneko, Tetsumin Lee, Toshihiro Nozato, Takashi Ashikaga, Masahiko Goya, Tetsuo Sasano
Summary: This study found that patients with a longer sinus node recovery time (SNRT) had a higher recurrence rate of atrial fibrillation after the first ablation and a higher inducibility of non-pulmonary vein triggers. Therefore, measuring SNRT may be useful for stratifying patients with persistent AF.
Article
Mathematical & Computational Biology
Tao Feng, Zhihua Deng
Summary: This study explored the predictive value of ECG based on an intelligent analysis algorithm for AF in elderly patients undergoing CABG. The Gentle AdaBoost algorithm showed better detection accuracy for arrhythmia and identified important indicators of AF after CABG, including Pmax and Pmin.
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Florian Baptiste, Jerome Kalifa, Cyril Durand, Edouard Gitenay, Michel Bremondy, Anis Ayari, Nicolas Maillot, Antonio Taormina, Aicha Fofana, Guillaume Penaranda, Sabrina Siame, Clement Bars, Julien Seitz
Summary: This study aimed to investigate the prevalence and electrophysiological characteristics of atrial fibrillation (AF) drivers arising from the right atrial appendage (RAA). The results showed that 7% of patients had RAA drivers, which were associated with the termination of AF.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Oussama M. Wazni, Gopi Dandamudi, Nitesh Sood, Robert Hoyt, Jaret Tyler, Sarfraz Durrani, Mark Niebauer, Kevin Makati, Blair Halperin, Andre Gauri, Gustavo Morales, Mingyuan Shao, Jeffrey Cerkvenik, Rachelle E. Kaplon, Steven E. Nissen
Summary: In this multicenter trial, cryoballoon ablation as initial therapy was found to be superior to drug therapy in preventing atrial arrhythmia recurrence in patients with paroxysmal atrial fibrillation. Serious procedure-related adverse events were uncommon.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Medicine, General & Internal
J. G. Andrade, M. W. Deyell, L. Macle, G. A. Wells, M. Bennett, V Essebag, J-F Roux, D. Yung, A. Skanes, Y. Khaykin, C. Morillo, U. Jolly, P. Novak, E. Lockwood, G. Amit, P. Angaran, J. Sapp, S. Wardell, S. Lauck, J. Cadrin-Tourigny, S. Kochhaeuser, A. Verma
Summary: This study evaluated the treatment effect of catheter cryoballoon ablation versus antiarrhythmic drug therapy for initial paroxysmal atrial fibrillation. The results showed that in the 3-year follow-up period, the catheter ablation group had a lower incidence of persistent atrial fibrillation and recurrent atrial tachyarrhythmia compared to the drug therapy group. Additionally, the proportion of time in atrial fibrillation was also lower in the ablation group. Therefore, catheter ablation is recommended as the initial treatment for initial paroxysmal atrial fibrillation.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
F. Halimi, P. Sabouret, J. P. Huberman, L. Ouazana, D. Guedj, K. Djouadi, T. S. Dhanjal, A. Goette, C. Lafont, Nicolas Lellouche
Summary: This study evaluated the prevalence and management of atrial fibrillation (AF) diagnosed in patients with high cardiovascular risk and non-documented clinical palpitation using 14-day continuous ECG-Holter monitoring. The results showed that AF was detected in 14% of the patients, and the prescription rate of anticoagulation and antiarrhythmic therapy in the AF detected population reached 90%.
CLINICAL RESEARCH IN CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Gregory Y. H. Lip, Marco Proietti, Tatjana Potpara, Moussa Mansour, Irina Savelieva, Hung Fat Tse, Andreas Goette, A. John Camm, Carina Blomstrom-Lundqvist, Dhiraj Gupta, Giuseppe Boriani
Summary: Stroke prevention in patients with atrial fibrillation has significantly improved with the introduction of non-vitamin K antagonist oral anticoagulants. Early rhythm control and cardiovascular risk factor management are also crucial in reducing the risk of stroke. Left atrial appendage occlusion or exclusion may be considered for patients who cannot undergo long-term oral anticoagulation. A holistic approach to atrial fibrillation management is recommended.
Review
Cardiac & Cardiovascular Systems
Jason G. Andrade, Oussama M. Wazni, Malte Kuniss, Nathaniel M. Hawkins, Marc W. Deyell, Gian-Battista Chierchia, Steven Nissen, Atul Verma, George A. Wells, Ricky D. Turgeon
Summary: Cryoballoon catheter ablation has been shown to significantly improve arrhythmia outcomes, produce clinically meaningful improvements in patient-reported outcomes, reduce subsequent health care resource use, and not increase the risk of serious adverse events compared with initial antiarrhythmic drug therapy in patients with treatment-naive AF.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Carmelo Dominici, Massimo Chello
Summary: Surgical ablation is an effective treatment for atrial fibrillation during cardiac surgery, improving the duration of atrial fibrillation and potentially enhancing quality of life. However, it carries a risk of pacemaker implantation and complications, which should be weighed against individual patient selection. Short-term outcomes support the efficacy of surgical ablation, but further research is needed to investigate long-term effects.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Dorte Marie Stavnem, Rakin Hadad, Bjorn Stroier Larsen, Olav Wendelboe Nielsen, Mark Aplin Frederiksen, Ulla Davidsen, Soren Hojbjerg, Finn Michael Karlsen, Maria Helena Dominguez Vall-Lamora, Hanne Kruuse Rasmusen, Ahmad Sajadieh
Summary: Prolonged electrocardiographic pauses of >= 2.5 s or >= 3.0 s are not markers for increased mortality in patients with atrial fibrillation, according to this real-life clinical study.
Article
Medicine, General & Internal
Fabien Squara, Didier Scarlatti, Sok-Sithikun Bun, Pamela Moceri, Emile Ferrari, Olivier Meste, Vicente Zarzoso
Summary: This study found that Fibrillatory Wave Amplitude (FWA) is unrelated to the complexity of atrial fibrillation (AF) but is mainly determined by the amount of viable atrial myocytes. Therefore, FWA should only be referred as a marker of atrial tissue pathology.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Andreas Haeberlin, Nikola Kozhuharov, Sven Knecht, Hildegard Tanner, Beat Schaer, Fabian Noti, Stefan Osswald, Helge Servatius, Samuel Baldinger, Jens Seiler, Anna Lam, Luke Mosher, Christian Sticherling, Laurent Roten, Michael Kuhne, Tobias Reichlin
Article
Cardiac & Cardiovascular Systems
Andreas Haeberlin, Marie-Theres Anwander, Thomas Kueffer, Maximilien Tholl, Samuel Baldinger, Helge Servatius, Anna Lam, Florian Franzeck, Babken Asatryan, Adrian Zurbuchen, Hildegard Tanner, Tobias Reichlin, Laurent Roten, Fabian Noti
Summary: The Beflex/Vega leads had a higher failure rate of over 10% after 3 years compared to a competitor lead. This is concerning as over 135,000 such leads are active worldwide.
Article
Cardiac & Cardiovascular Systems
Babken Asatryan, Lauren Yee, Yael Ben-Haim, Stephan Dobner, Helge Servatius, Laurent Roten, Hildegard Tanner, Lia Crotti, Jonathan R. Skinner, Carol Ann Remme, Philippe Chevalier, Argelia Medeiros-Domingo, Elijah R. Behr, Tobias Reichlin, Katja E. Odening, Andrew D. Krahn
Summary: Sex-related differences in cardiac channelopathies are increasingly recognized, with varying risks and clinical features between men and women in different conditions, mainly influenced by age and sex hormones. While sex-specific predictors have been identified, gaps in the mechanistic understanding of these differences remain, highlighting the need for further research to address these disparities and improve patient outcomes.
Article
Cardiac & Cardiovascular Systems
Babken Asatryan, Jens Seiler, Luc Bourquin, Sven Knecht, Helge Servatius, Antonio Madaffari, Samuel H. Baldinger, Patrick Badertscher, Thomas Kuffer, Florian Spies, Hildegard Tanner, Michael Kuhne, Stefan Osswald, Laurent Roten, Christian Sticherling, Tobias Reichlin
Summary: This study demonstrates that pre-procedural burden of idiopathic premature ventricular complexes does not predict the outcome of catheter ablation, suggesting that ablation may be a reasonable treatment option for patients with symptomatic yet rare PVCs.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Anna Lam, Thomas Kueffer, Lukas Hunziker, Nikolas Nozica, Babken Asatryan, Florian Franzeck, Antonio Madaffari, Andreas Haeberlin, Aline Muehl, Helge Servatius, Jens Seiler, Fabian Noti, Samuel H. Baldinger, Hildegard Tanner, Stephan Windecker, Tobias Reichlin, Laurent Roten
Summary: Chemical ablation by retrograde infusion of ethanol into the vein of Marshall (VOM-EI) is a feasible, safe, and effective technique to achieve acute mitral isthmus block. The study demonstrated successful mitral isthmus block with VOM-EI, with some patients requiring additional ablation procedures and experiencing arrhythmia recurrence during follow-up.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Sven Knecht, Christian Sticherling, Laurent Roten, Patrick Badertscher, Laureve Chollet, Thomas Kuffer, Florian Spies, Antonio Madaffari, Aline Muhl, Samuel H. Baldinger, Helge Servatius, Stefan Osswald, Tobias Reichlin, Michael Kuhne
Summary: The study compared procedural and technical differences of a novel cryoballoon ablation catheter to a standard cryoballoon catheter for pulmonary vein isolation in patients with atrial fibrillation. Results showed slightly more freezes with the novel catheter, lower temperatures during vein isolation, and similar acute efficacy and time to isolation compared to the standard catheter.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Felix Neugebauer, Fabian Noti, Stephan van Gool, Laurent Roten, Samuel H. Baldinger, Jens Seiler, Antonio Madaffari, Helge Servatius, Adrian Ryser, Hildegard Tanner, Tobias Reichlin, Andreas Haeberlin
Summary: This study investigated AV synchrony and the impact of programming adjustments on AV synchrony in outpatients with leadless VDD pacemakers. The study found that achieving successful VDD pacing during higher sinus rates is challenging and often requires multiple reprogramming to optimize AV sequential pacing.
Article
Cardiac & Cardiovascular Systems
Helge Servatius, Thomas Kuffer, Samuel H. Baldinger, Babken Asatryan, Jens Seiler, Hildegard Tanner, Jan Novak, Anna Lam, Fabian Noti, Andreas Haeberlin, Antonio Madaffari, Romy Sweda, Aline Muhl, Mattia Branca, Sophie Dutschler, Gabor Erdoes, Frank Stuber, Lorenz Theiler, Tobias Reichlin, Laurent Roten
Summary: This study aimed to compare the efficacy of DEX and PRO in AF ablation procedures, and found that there was no significant difference in primary endpoints between the two groups. However, patients in the PRO group reported higher satisfaction with the procedural sedation.
Article
Medicine, General & Internal
Laurent Roten, Eleni Goulouti, Anna Lam, Elena Elchinova, Nikolas Nozica, Alessandro Spirito, Severin Wittmer, Mattia Branca, Helge Servatius, Fabian Noti, Jens Seiler, Samuel H. Baldinger, Andreas Haeberlin, Stefano de Marchi, Babken Asatryan, Nicolas Rodondi, Jacques Donze, Drahomir Aujesky, Hildegard Tanner, Tobias Reichlin, Peter Juni
Summary: In a large hospital-based patient population aged 65-84 years, the prevalence of clinical AF and of screen-detected AF was 22.2% and 3.8%, respectively, and significantly higher in males than females.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Helge Servatius, Simon Raab, Babken Asatryan, Andreas Haeberlin, Mattia Branca, Stefano de Marchi, Nicolas Brugger, Nikolas Nozica, Eleni Goulouti, Elena Elchinova, Anna Lam, Jens Seiler, Fabian Noti, Antonio Madaffari, Hildegard Tanner, Samuel H. Baldinger, Tobias Reichlin, Matthias Wilhelm, Laurent Roten
Summary: Structural and electrical atrial remodeling is more advanced in patients with hypertrophic cardiomyopathy (HCM) compared to patients with hypertensive heart disease (HHD) and athletes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Adrian Thomas Huber, Severin Fankhauser, Laureve Chollet, Severin Wittmer, Anna Lam, Samuel Baldinger, Antonio Madaffari, Jens Seiler, Helge Servatius, Andreas Haeberlin, Fabian Noti, Nicolas Brugger, Hendrik von Tengg-Kobligk, Christoph Grani, Laurent Roten, Hildegard Tanner, Tobias Reichlin
Summary: The presence of left atrial enhancing epicardial adipose tissue is associated with recurrence after atrial fibrillation ablation, indicating its potential as a predictive marker for treatment outcomes.
Article
Cardiac & Cardiovascular Systems
Barbara Steinhauer, Sophie Dutschler, Jasmin Spicher, Sarah Aerschmann, Nicole Ambord, Joanna Bartkowiak, Serlha Tawo, Gregor Thalmann, Helge Servatius, Fabian Noti, Jens Seiler, Samuel Baldinger, Andreas Haeberlin, Antonio Madaffari, Hildegard Tanner, Tobias Reichlin, Laurent Roten
Summary: The study compared nurse-led ICM implantation with physician-led ICM implantation in terms of patient satisfaction, adverse events during implantation, and ICM re-interventions. The results showed that nurse-led ICM implantation service can ensure patient satisfaction while reducing physician workload.
EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING
(2023)
Meeting Abstract
Medicine, General & Internal
T. Kueffer, S. H. Baldinger, H. Servatius, A. Madaffari, J. Seiler, A. Muhl, F. Franzeck, G. Thalmann, B. Asatryan, A. Haeberlin, F. Noti, H. Tanner, L. Roten, T. Reichlin
SWISS MEDICAL WEEKLY
(2022)
Article
Medicine, General & Internal
Nikolas Nozica, Anna Lam, Eleni Goulouti, Elena Elchinova, Alessandro Spirito, Mattia Branca, Helge Servatius, Fabian Noti, Jens Seiler, Samuel H. Baldinger, Andreas Haeberlin, Stefano F. de Marchi, Babken Asatryan, Nicolas Rodondi, Jacques Donze, Drahomir Aujesky, Hildegard Tanner, Tobias Reichlin, Peter Juni, Laurent Roten
Summary: The STAR-FIB study programme aims to determine the age- and sex-specific prevalence of silent atrial fibrillation and develop a clinical prediction model to identify patients at risk of undiagnosed atrial fibrillation in a hospitalised patient population. The study includes a prospective cohort study and a case-control study, with the primary endpoint being any episode of atrial fibrillation or atrial flutter of >= 30 seconds duration. The study will estimate the age- and sex-specific prevalence of silent atrial fibrillation and validate a clinical prediction model to identify patients at risk.
SWISS MEDICAL WEEKLY
(2021)
Article
Cardiac & Cardiovascular Systems
Annina Stauber, Hildegard Tanner, Fabian Noti, Laurent Roten, Jens Seiler, Anna Lam, Argelia Medeiros-Domingo, Helge Servatius, Van Nam Tran, Thierry Carrel, Alberto Weber
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
(2020)