Journal
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Volume 41, Issue 1, Pages 99-106Publisher
SPRINGER
DOI: 10.1007/s00249-011-0763-7
Keywords
DNA; Optical tweezers; Colored noise; Power spectral density
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Funding
- MIIN (Spain), Fundacio privada Cellex Barcelona [FIS2008-00114]
- ICREA Funding Source: Custom
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We studied fluctuations of an optically trapped bead connected to a single DNA molecule anchored between the bead and a cover glass or between two optically trapped beads. Power spectral densities of the bead position for different extensions of the molecule were compared with the power spectral density of the position fluctuations of the same bead without the molecule attached. Experiments showed that the fluctuations of the DNA molecule extended up to 80% by a force of 3 pN include the colored noise contribution with spectral dependence 1/f (alpha) with alpha similar to 0.75.
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