Article
Psychiatry
Na Hu, Wei Li, Hu Deng, Jiaqi Song, Hanxue Yang, Jiabao Chai, Wenqian Huang, Hong Wang, Xuanzi Zhou, Pan Zhang, Sushuang He, Yonghua Cui, Tengteng Fan, Ying Li
Summary: This study evaluated the clinical symptoms, antipsychotic adverse reactions, and social functioning of 283 hospitalized patients with chronic schizophrenia. Depressive symptoms, extrapyramidal symptoms, and positive symptoms were found to be significant contributors to secondary negative symptoms. Negative symptoms were found to play a significant mediating role in the effect of depressive and positive symptoms on social functioning.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Clinical Neurology
Veera K. Malkki, Tom H. Rosenstrom, Markus M. Jokela, Suoma E. Saarni
Summary: This study examined the impact of depression symptoms on functioning improvement during psychotherapy. The findings showed that changes in depressed mood or hopelessness, sleep problems, fatigue, and lack of interest or pleasure were associated with improved functioning during psychotherapy, while baseline measures of depression symptoms were not related to changes in functioning.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Clinical Neurology
Cheng Bian, Wei-Wei Zhao, Shi-Rui Yan, Shu-Yan Chen, Yin Cheng, Yan-Hong Zhang
Summary: Interpersonal psychotherapy (IPT) has significant effects on improving social functioning and reducing depression and anxiety. However, its effect on overall functioning requires further research. Subgroup analysis suggests that IPT is effective in improving social functioning for adolescent depression and perinatal depression, but not significant for adult depression.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Medicine, General & Internal
Gonzalo Salazar de Pablo, Filippo Besana, Vincenzo Arienti, Ana Catalan, Julio Vaquerizo-Serrano, Anna Cabras, Joana Pereira, Livia Soardo, Francesco Coronelli, Simi Kaur, Josette da Silva, Dominic Oliver, Natalia Petros, Carmen Moreno, Ana Gonzalez-Pinto, Covadonga M. Diaz-Caneja, Jae Il Shin, Pierluigi Politi, Marco Solmi, Renato Borgatti, Martina Maria Mensi, Celso Arango, Christoph U. Correll, Philip McGuire, Paolo Fusar-Poli
Summary: The meta-analysis study revealed that CHR-P individuals show improvements in symptoms and functional outcomes over time, but sustaining these improvements in the long term is challenging, with less than half of patients achieving full remission.
Article
Psychology, Clinical
Kristin M. Mignogna, Fernando S. Goes
Summary: In this study using the STEP-BD study, trajectories of bipolar disorder were identified in terms of depressive symptoms, manic symptoms, and psychosocial functioning. Different trajectories showed varying degrees of association with negative clinical risk factors.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Biology
Xinrui Wang, Zhao Chang, Rong Wang
Summary: The nested spectral partition (NSP) method, along with fMRI data, machine learning, and gene ontology analysis, reveals that positive and negative symptoms of schizophrenia have opposite effects on the functional organization of resting-state brains. This research sheds light on the neural basis of schizophrenia and could contribute to more accurate diagnostic criteria for the disease.
COMMUNICATIONS BIOLOGY
(2023)
Article
Clinical Neurology
Emilia L. Mielke, Julian Koenig, Sabine C. Herpertz, Sylvia Steinmann, Corinne Neukel, Pelin Kilavuz, Patrice van der Venne, Katja Bertsch, Michael Kaess
Summary: Interpersonal dysfunction is a core symptom of borderline personality disorder (BPD), and recent research suggests that low levels of oxytocin in plasma may be related to this disorder. This study examined plasma oxytocin levels in 131 female BPD patients, finding that they had reduced levels compared to non-BPD controls, and this was independent of age. Plasma oxytocin was also negatively associated with the number of BPD symptoms, and there was a mediating effect of adverse childhood experiences on the relationship between BPD symptoms and oxytocin levels.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2023)
Article
Business
Sylvia Lopez Davis, Longinos Marin Rives, Salvador Ruiz-de-Maya
Summary: While existing literature on consumer behavior has discussed responsible consumption, this research introduces the concept of personal social responsibility (PSR) which goes beyond consumption and encompasses various dimensions of individual behavior. The study develops a scale to measure PSR and finds that it includes economic, legal, ethical, philanthropic, and environmental aspects of individual behavior. Moreover, the research demonstrates that perceived consumer effectiveness and collectivism positively influence personal responsibility behaviors, and being more responsible is associated with higher self-esteem and life satisfaction.
CORPORATE SOCIAL RESPONSIBILITY AND ENVIRONMENTAL MANAGEMENT
(2021)
Article
Neurosciences
Shiu F. Wong, Christopher Cardoso, Mark A. Orlando, Christopher A. Brown, Mark A. Ellenbogen
Summary: The study demonstrates the complex effects of oxytocin on social cognition and its regulation of depressive symptoms. Oxytocin increases the vividness of recalled memories in a social context, while it may lead to more negative memories in a non-social context, especially in individuals with elevated depressive symptoms.
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2022)
Article
Psychiatry
Sarah E. Herniman, Lisa J. Phillips, Stephen J. Wood, Sue M. Cotton, Edith J. Liemburg, Kelly A. Allott
Summary: This study aimed to understand the interrelationships between positive and negative symptoms of recent-onset schizophrenia spectrum disorders and co-occurring depressive symptoms. Results showed that positive symptoms were associated with depressive and negative symptoms, while negative symptoms were more likely to be associated with depressive symptoms. Suspiciousness and stereotyped thinking bridged between positive and depressive symptoms, and apparent sadness and lassitude bridged between negative and depressive symptoms.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Clinical Neurology
Blaire C. Pingeton, Amy Cochran, Sherryl H. Goodman, Heidemarie Laurent, Marissa D. Sbrilli, Bettina Knight, D. Jeffrey Newport, Zachary N. Stowe
Summary: This study aimed to test whether measuring positive affect could improve a transdiagnostic model of depression symptoms in perinatal patients and replicate the model in another sample. The results showed that adding a positive affect factor improved the model fit in both samples. These findings have implications for clinicians and researchers in understanding and treating depression symptoms in perinatal patients, as well as developing more effective tools for screening, prevention, and intervention.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Timm Rosburg, Regina Kunz, Bruno Trezzini, Urban Schwegler, Joerg Jeger
Summary: This study evaluated the role of Mini-ICF-APP ratings in psychiatric work disability evaluations, finding that ratings varied with primary psychiatric diagnoses and were strongly correlated with RWC estimates. The study showed differences in ratings between claimants with different psychiatric diagnoses, with a strong negative correlation between Mini-ICF-APP ratings and estimated RWC.
Article
Psychiatry
Keane Lim, Attilio Rapisarda, Richard S. E. Keefe, Jimmy Lee
Summary: This study examined the psychometric properties of a social skills measure (HiSoC) in individuals at Ultra-High Risk (UHR) of psychosis, and evaluated the relationship between social skills, negative symptoms, and real-world functioning. The results showed that HiSoC could differentiate UHR individuals from healthy controls, and the social amotivation subdomain of negative symptoms was the strongest predictor of real-world functioning.
ASIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Psychiatry
Chaoqing Yang, Linlin He, Yucheng Liu, Ziyang Lin, Lizhu Luo, Shan Gao
Summary: Depressed individuals are more sensitive to negative information and have a reduced ability to focus on positive information. In this study, we examined the inhibitory control over attentional bias on social evaluation in individuals with depression. The results showed that depressed individuals had longer latencies and made more errors in anti-saccade trials compared to non-depressed individuals. Furthermore, depressed individuals spent more time making correct anti-saccade responses to negative social feedback than to positive ones, while non-depressed individuals had longer correct anti-saccade latencies for positive evaluations. These findings suggest that depressed individuals have impaired attention control for self-referential evaluations, particularly those with negative valence.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Article
Geriatrics & Gerontology
Carlos Vara-Garcia, Brent T. Mausbach, Rosa Romero-Moreno, Andres Losada-Baltar, Dilip Jeste, Igor Grant
Summary: This study examined the associations between caregivers' cognitive and behavioral coping strategies and depressive symptoms. The results showed that different coping strategies were associated with different components of depressive symptomatology. Personal mastery and coping self-efficacy were found to be important factors in predicting mood outcomes.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2022)
Article
Clinical Neurology
Patricia Correa-Ghisays, Joan Vicent Sanchez-Orti, Vicent Balanza-Martinez, Gabriel Selva-Vera, Joan Vila-Frances, Rafael Magdalena-Benedito, Victor M. Victor, Irene Escribano-Lopez, Antonio Hernandez-Mijares, Juliana Vivas-Lalinde, Constanza San-Martin, Benedicto Crespo-Facorro, Rafael Tabares-Seisdedos
Summary: The study revealed overlapping neurocognitive impairments across somatic and psychiatric disorders, as well as social functioning impairment in almost all disorders. Transdiagnostic deficits remained stable over a 1-year follow-up and accurately differentiated individuals with somatic and psychiatric disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychiatry
Ana M. Sanchez-Torres, Victor Peralta, Gustavo J. Gil-Berrozpe, Gisela Mezquida, Mariola Molina-Garcia, Silvia Amoretti, Antonio Lobo, Ana Gonzalez-Pinto, Jessica Merchan-Naranjo, Iluminada Corripio, Eduard Vieta, Elena de la Serna, Daniel Berge, Miguel Bernardo, Manuel J. Cuesta
Summary: This study used network analysis to examine the structure of cognitive performance in psychotic disorders and found many similarities in the network structure between FEP patients and healthy controls. The study showed that verbal memory, attention, working memory, and executive function are central dimensions in the cognitive network, which has important implications for cognitive rehabilitation and treatment.
SCHIZOPHRENIA RESEARCH
(2022)
Review
Environmental Sciences
Vicent Balanza-Martinez, Jose Cervera-Martinez
Summary: The study aimed to review the impact of nature exposure and screen time on depression, finding that walks in natural environments may help reduce symptoms in clinical depression patients, but research on screen time is limited.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Mario Simjanoski, Taiane de Azevedo Cardoso, Bianca Wollenhaupt-Aguiar, Bianca Pfaffenseller, Vicent Balanza-Martinez, Luciano Minuzzi, Flavio Kapczinski
Summary: This study investigated the association between lifestyle behaviors and symptoms of depression and anxiety during the COVID-19 pandemic in Canada. The results showed that unhealthy lifestyle behaviors were associated with depression and anxiety symptoms, emphasizing the importance of lifestyle medicine education and targeted interventions.
AMERICAN JOURNAL OF LIFESTYLE MEDICINE
(2023)
Article
Clinical Neurology
M. Vicent-Gil, M. Serra-Blasco, G. Navarra-Ventura, J. Trujols, V Balanza-Martinez, M. J. Portella, N. Cardoner
Summary: This study explored the relationship between clinical remission, functional remission, and patient's perception of recovery in individuals with major depression disorder. It also identified the factors associated with functional and subjective remission. The findings showed that depressive symptoms and cognitive function were related to psychosocial functioning, while depressive symptoms and attention and executive function were significant factors for self-perception of remission.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Psychiatry
Tamsyn E. Van Rheenen, Elysha Ringin, James A. Karantonis, Lisa Furlong, Kiymet Bozaoglu, Susan L. Rossell, Michael Berk, Vicent Balanza-Martinez
Summary: This study examined the role of vitamin D in bipolar disorder (BD) patients and found no significant differences in vitamin D levels or deficiency status between BD patients and healthy controls. The study also found no association between vitamin D and clinical symptoms or global cognition in BD.
PSYCHIATRY RESEARCH
(2023)
Article
Neurosciences
Norma Verdolini, Gisela Mezquida, Isabel Valli, Clemente Garcia-Rizo, Manuel Cuesta, Eduard Vieta, Miquel Bioque, Antonio Lobo, Ana Gonzalez-Pinto, Laura Pina-Camacho, Iluminada Corripio, Marina Garriga, Inmaculada Baeza, Laura Martinez-Sadurni, Byron Bitanihirwe, Mary Cannon, Miquel Bernardo
Summary: This study examined the relationship between obstetric complications (OCs) and clinical phenotypes in patients with a first episode of psychosis (FEP). The results showed that OCs were associated with more severe psychopathology, highlighting the importance of OCs in understanding the heterogeneity of clinical presentation in psychosis.
ACTA NEUROPSYCHIATRICA
(2023)
Review
Psychiatry
Dharmanand Ramnarain, Sjaak Pouwels, Sol Fernandez-Gonzalo, Guillem Navarra-Ventura, Vicent Balanza-Martinez
Summary: Delirium is common in the ICU and has a significant impact on the neurocognitive and psychiatric state of survivors, referred to as post-intensive care syndrome (PICS). This review discusses the latest screening and follow-up options for psychological and cognitive sequelae of PICS. The confusion assessment method for the ICU and the intensive care delirium screening checklist are commonly used tools for diagnosing delirium in the ICU. Survivors often experience depression, anxiety, post-traumatic stress disorder, and long-term cognitive impairment. Implementing screening and follow-up protocols for PICS sequelae is crucial for early detection and management.
ACTA PSYCHIATRICA SCANDINAVICA
(2023)
Article
Psychiatry
Isabel Valli, Alex Gonzalez Segura, Norma Verdolini, Clemente Garcia-Rizo, Daniel Berge, Inmaculada J. Baeza, Manuel Cuesta, Ana Gonzalez-Pinto, Antonio Lobo, Anabel Martinez-Aran, Gisela Mezquida, Laura Pina-Camacho, Alexandra Roldan Bejarano, Sergi Mas, Philip McGuire, Miquel Bernardo, Eduard Vieta
Summary: Obstetric complications (OCs) are important factors contributing to psychosis risk. This study found that complications of pregnancy and abnormalities of foetal growth are significantly associated with psychosis, while complications of delivery are not. There is no significant interaction between genetic risk and OCs. Different types of OCs may have different impacts on psychosis risk based on their nature and timeframe.
ACTA PSYCHIATRICA SCANDINAVICA
(2023)
Article
Clinical Neurology
Paola Lavin, Soham Rej, Andrew T. Olagunju, Antonio L. Teixeira, Annemieke Dols, Martin Alda, Osvaldo P. Almeida, Kursat Altinbas, Vicent Balanza-Martinez, Izabela G. Barbosa, Hilary P. Blumberg, Farren Briggs, Cynthia Calkin, Kristin Cassidy, Brent P. Forester, Orestes V. Forlenza, Tomas Hajek, Barthomeus C. M. Haarman, Esther Jimenez, Beny Lafer, Benoit Mulsant, Stephen O. Oluwaniyi, Regan Patrick, Joaquim Radua, Sigfried Schouws, Harmehr Sekhon, Christian Simhandl, Jair C. Soares, Shang-Ying Tsai, Eduard Vieta, Luca M. Villa, Martha Sajatovic, Lisa T. Eyler
Summary: By 2030, more than 50% of individuals with bipolar disorder will be aged 50 years or older. However, there is a lack of research on older age bipolar disorder. This study developed initial recommendations for essential dimensions and variables for data collection in older age bipolar disorder, which can guide future research and clinical practice.
Article
Psychology, Developmental
Inmaculada Baeza, Elena de la Serna, Gisela Mezquida, Manuel Cuesta, Eduard Vieta, Silvia Amoretti, Antonio Lobo, Ana Gonzalez-Pinto, Covadonga Diaz-Caneja, Iluminada Corripio, Isabel Valli, Olga Puig, Anna Mane, Miquel Bioque, Miriam Ayora, Miquel Bernardo, Josefina Castro-Fornieles
Summary: This study investigated the influence of age (early onset psychosis-EOP vs. adult onset psychosis-AOP) and diagnosis (schizophrenia spectrum disorders-SSD vs. bipolar disorders-BD) on the duration of untreated psychosis (DUP) and prodromal symptoms in patients with a first episode of psychosis. The results revealed that EOP patients had more prodromal symptoms and a longer DUP compared to AOP patients. Moreover, SSD patients had a significantly longer DUP than BD patients, and they also exhibited different profiles of prodromal symptoms. Understanding these differences can help improve the early detection of psychosis among minors.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychiatry
I. Zorrilla, S. Lopez-Zurbano, S. Alberich, I. Barbero, P. Lopez-Pena, E. Garcia-Corres, J. P. Chart Pascual, J. M. Crespo, C. de Dios, V. Balanza-Martinez, A. Gonzalez-Pinto
Summary: This study assessed the influence of lifestyle factors on lithium levels in patients with bipolar disorder. It found that higher levels of physical activity and BMI contribute to lower lithium levels. Patients should be aware of these relationships to improve their perception of control and self-management. Lifestyle-based interventions contribute to establishing a more personalized medicine.
INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS
(2023)
Review
Behavioral Sciences
Mario Simjanoski, Swara Patel, Raquel De Boni, Vicent Balanza-Martinez, Benicio N. Frey, Luciano Minuzzi, Flavio Kapczinski, Taiane de Azevedo Cardoso
Summary: This review and meta-analysis examine interventions targeting the 6 pillars of Lifestyle Psychiatry for bipolar disorder. The study found that sleep, physical activity, and diet were the most targeted domains, while substance use, stress management, and social relationships were least targeted. Combined diet and physical activity interventions showed significant improvement in depressive symptoms and functioning. Sleep interventions also led to significant improvements in depressive symptoms. Future research should focus on developing multidimensional lifestyle interventions for better outcomes.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Medicine, General & Internal
Marcelo Ribeiro-Alves, Giovanna Lucieri Costa, Jurema Correa da Mota, Taiane de Azevedo Cardoso, Keila Cerezer, Thais Martini, Marina Ururahy Soriano de Sousa, Francisco Bastos, Vicent Balanza-Martinez, Flavio Kapczinski, Raquel Brandini De Boni
Summary: The objective of this study was to evaluate changes in lifestyle among the Brazilian general population during the first year of the pandemic. The findings indicate that individuals from a large middle-income country, such as Brazil, struggled to restore diet and social relationships after 1 year of the pandemic. These findings have implications for monitoring the long-term consequences of the pandemic, as well as future pandemics.
Article
Clinical Neurology
Joan Vicent Sanchez-Orti, Patricia Correa-Ghisays, Vicent Balanza-Martinez, Gabriel Selva-Vera, Joan Vila-Frances, Rafael Magdalena-Benedito, Constanza San-Martin, Victor M. Victor, Irene Escribano-Lopez, Antonio Hernandez-Mijares, Juliana Vivas-Lalinde, Benedicto Crespo-Facorro, Rafael Tabares-Seisdedos
Summary: This study aimed to identify peripheral biomarkers suitable to signal memory decline from a transdiagnostic and longitudinal perspective. The results showed that inflammation and lipid metabolism are associated with memory problems in various conditions such as diabetes and severe mental illnesses. A panel of biomarkers may be an effective approach to identify individuals at risk of neurocognitive impairment. These findings have potential implications for early intervention and precision medicine in these disorders.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2023)
