Sodium channel block by ranolazine in an experimental model of stretch-related atrial fibrillation: prolongation of interatrial conduction time and increase in post-repolarization refractoriness

2012 focused update of the ESC Guidelines for the management of atrial fibrillation

(2012) et al.   EUROPACE

Further insights into the underlying electrophysiological mechanisms for reduction of atrial fibrillation by ranolazine in an experimental model of chronic heart failure

(2012) Gerrit Frommeyer et al.   EUROPEAN JOURNAL OF HEART FAILURE

Comparison of Effectiveness and Safety of Ranolazine Versus Amiodarone for Preventing Atrial Fibrillation After Coronary Artery Bypass Grafting

(2011) Ronald H. Miles et al.   AMERICAN JOURNAL OF CARDIOLOGY

Mechanisms of atrial-selective block of Na+ channels by ranolazine: I. Experimental analysis of the use-dependent block

(2011) Andrew C. Zygmunt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A new mechanism preventing proarrhythmia in chronic heart failure: rapid phase-III repolarization explains the low proarrhythmic potential of amiodarone in contrast to sotalol in a model of pacing-induced heart failure

(2011) Gerrit Frommeyer et al.   EUROPEAN JOURNAL OF HEART FAILURE

Ranolazine Reduces Ventricular Tachycardia Burden and ICD Shocks in Patients with Drug-Refractory ICD Shocks

(2011) T. JARED BUNCH et al.   PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY

The Antianginal Agent Ranolazine is a Potent Antiarrhythmic Agent that Reduces Ventricular Arrhythmias: Through a Mechanism Favoring Inhibition of Late Sodium Channel

(2010) Robert A. Kloner et al.   Cardiovascular Therapeutics

Altered Na+Currents in Atrial Fibrillation

(2010) Samuel Sossalla et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Late Na+Current Inhibition by Ranolazine Reduces Torsades de Pointes in the Chronic Atrioventricular Block Dog Model

(2010) Gudrun Antoons et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Ranolazine, an antianginal agent, markedly reduces ventricular arrhythmias induced by ischemia and ischemia-reperfusion

(2009) Arvinder K. Dhalla et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Use-dependent block of cardiac late Na+ current by ranolazine

(2009) Sridharan Rajamani et al.   HEART RHYTHM

Ranolazine Exerts Potent Effects on Atrial Electrical Properties and Abbreviates Atrial Fibrillation Duration in the Intact Porcine Heart

(2009) KAPIL KUMAR et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY

Pathology-specific effects of the IKur/Ito/IK,ACh blocker AVE0118 on ion channels in human chronic atrial fibrillation

(2008) T Christ et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antiarrhythmic effects of ranolazine in canine pulmonary vein sleeve preparations

(2008) Serge Sicouri et al.   HEART RHYTHM

Ranolazine Shortens Repolarization in Patients with Sustained Inward Sodium Current Due to Type-3 Long-QT Syndrome

(2008) ARTHUR J. MOSS et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY

Late sodium current inhibition as a new cardioprotective approach

(2008) Sharon L. Hale et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Postconditioning fails to improve no reflow or alter infarct size in an open-chest rabbit model of myocardial ischemia-reperfusion

(2007) Sharon L. Hale et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Molecular basis of ranolazine block of LQT-3 mutant sodium channels: evidence for site of action

(2006) Sandra Fredj et al.   BRITISH JOURNAL OF PHARMACOLOGY