Article
Chemistry, Analytical
Baojun Long, Yuanmeng Zhao, Peiyu Cao, Wen Wei, Yan Mo, Juejing Liu, Cheng-Jun Sun, Xiaofeng Guo, Changsheng Shan, Ming-Hua Zeng
Summary: The researchers designed a catalyst composed of single-atom Pt supported on Ni(OH)(2) nanoplates/nitrogen-doped graphene for constructing an electrochemical nonenzymatic glucose sensor. The catalyst exhibited low anode peak potential and high sensitivity, with excellent selectivity, short response time, and high stability. The improved performance of the catalyst was attributed to the stronger binding strength of glucose on the single-atom Pt active centers and their surrounding Ni atoms, as well as the fast electron transfer ability of the conductive graphene.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Yilin Chen, Lu Yang, Xin Tang, Yu Zhang, Zhiyuan He, Yanying Liu, Xue Jiang, Xiaoli Xiong
Summary: In this study, nickel hydroxide nanoflake array was prepared on carbon cloth using a rapid and simple microplasma method. The resulting Ni(OH)(2) NA/CC electrode exhibited excellent electrocatalytic activity as well as non-enzymatic sensing properties for detecting glucose.
Article
Chemistry, Inorganic & Nuclear
Yingzhen Zhang, Yingying Song, Yancai Li
Summary: A simple and environmentally friendly autocatalytic reduction process was developed for the synthesis of Au/Ni(OH)(2)nanocomposites, which exhibit excellent electrocatalytic properties, particularly high sensitivity and a wide linear range for glucose oxidation.
JOURNAL OF CLUSTER SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Qian Zhang, Panpan Li, Jun Wu, Yi Peng, Huan Pang
Summary: 2D metal-organic frameworks (MOFs) have shown great promise as electrochemical sensing materials. In this study, a simple hydrothermal synthesis method was used to prepare pyridine-regulated lamellar Ni-MOFs with ultrathin and well-defined 2D morphology. Compared with bulk MOFs, the 2D lamellar Ni-MOF exhibited higher surface area and active site density, leading to improved electrochemical glucose sensing performance.
Article
Electrochemistry
Muhammad Waqas, Chengzhou Liu, Qiulan Huang, Xiaoxia Zhang, Youjun Fan, Zhe Jiang, Xiaoqu Wang, Wei Chen
Summary: This study presents the design of a novel nanostructure for non-enzymatic electrochemical determination of glucose. The morphological evolution of the nanostructure was achieved through control over reaction conditions, and the resulting catalysts were evaluated using spectroscopic, microscopic, and electrochemical characterization tools. The designed catalyst exhibited excellent electrocatalytic efficiency and glucose sensing performance.
ELECTROCHIMICA ACTA
(2022)
Article
Nanoscience & Nanotechnology
Haiyang Wang, Zhulin Niu, Zhikun Peng, Xianli Wu, Caiyan Gao, Shufang Zhao, Young Dok Kim, Han Wu, Xin Du, Zhongyi Liu, Baojun Li
Summary: Clearly defining responsibilities and establishing synergy between different active phases is crucial for improving the hydrogen evolution reaction process using heterostructure catalysts. This study successfully designed a three-dimensional hollow structure integrating CoxNi(1-x)(OH)(2) with MoS2 nanosheets, which resulted in dual active phases and optimized hydrogen evolution over a wide pH range.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Johvan O. Hill-Dick, Alexis Harmon, Wei Cao, Kishor K. Sadasivuni, Mehran Elahi, Adetayo Adedeji, Hani E. Elsayed-Ali, Gymama Slaughter, Kapil Kumar, Mohammad Asadi, Bijandra Kumar
Summary: Nonenzymatic glucose sensors based on nanocoral reduced Ag exhibit significantly higher sensitivity and stability, operating at low potentials and detecting glucose concentrations linearly in a wide range from 100 uM to 2.5 mM.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Chemistry, Physical
Yan Zhang, Donghui Zheng, Shuming Liu, Shengyao Qin, Xinhao Sun, Zhifeng Wang, Chunling Qin, Yongyan Li, Jun Zhou
Summary: Flexible sandwich beta-Ni(OH)(2) nanopetals/nanoporous Ni/metallic glass (beta-Ni(OH)(2)/NP-Ni/MG) electrodes were successfully fabricated for non-enzyme glucose sensor applications, showing high sensitivity, wide linear detection range, anti-interference ability, and long-term stability.
APPLIED SURFACE SCIENCE
(2021)
Article
Engineering, Electrical & Electronic
Shuai Chen, Dongzhi Zhang, Yan Yang, Xiaoshuang Song
Summary: A high sensitivity, low cost non-enzymatic glucose sensor was successfully developed on a printed circuit board substrate, showing excellent sensor performance and application prospects.
IEEE SENSORS JOURNAL
(2021)
Article
Chemistry, Physical
Liu-Han Yang, Rui Luo, Xiao-Ju Wen, Zong-Tang Liu, Zheng-Hao Fei, Lin Hu
Summary: Rechargeable zinc-air batteries are considered promising for renewable energy conversion, but the lack of efficient electrocatalysts for oxygen evolution and reduction reactions has hindered their application. A green and facile strategy was developed to synthesize Ni@CNT nanostructures, showing superior performance in OER and ORR, paving the way for energy device development.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Engineering, Electrical & Electronic
Tianheng Sun, Xin Cheng, Dongzhi Zhang
Summary: This study reported a low-cost, highly sensitive nonenzymatic glucose sensor based on CuCo2O4 nanoparticles. The CuCo2O4 nanoparticles were synthesized using oxalic acid and sodium hydroxide, and exhibited superior glucose sensing performance compared to NaOH-assisted CuCo2O4. The sensor showed good selectivity, repeatability, and long-term stability.
IEEE SENSORS JOURNAL
(2022)
Article
Chemistry, Analytical
Zhitao Shao, Qiyue Gao, Simin Sun, Lili Wu, Wei Feng
Summary: In this study, MOF-derived porous CuO nanosheets and CuO/CNT (7:3) NEGSs with high sensitivity, fast response time, and excellent selectivity were synthesized. The superior glucose sensing properties were attributed to the synergistic effect of MOF-derived CuO and CNT, where MOF-derived CuO nanosheets provided more active sites and CNT improved the conductivity and ion diffusion in the electrode. The CuO/CNT (7:3) NEGSs also demonstrated good recovery for glucose detection in human urine and beverages, suggesting their potential as electrode materials for high-performance NEGSs.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Physical
Shengzhe Wang, Hongxia Lv, Chengyu Jin, Yu Wang, Huangzhao Wei, Chenglin Sun, Lian Yu, Lei Ma, Xiangnan Li, Xiaowei Liu
Summary: A series of Ru-Ti-Ni/CNT electrodes were synthesized to degrade levofloxacin in wastewater, showing a notable synergistic effect. The reaction kinetics constant of Ru-Ti-Ni/CNT with a Ru: Ti ratio of 10:0 outperforms Ni/CNT by 3.7 times and CNT alone by 16.4 times. Comprehensive characterizations revealed its morphology and structure, with Ru nanoparticles shielding Ni and Ni single-atoms facilitating electron transfer to generate abundant reactive oxygen radicals (ROS) for pollutant degradation.
CATALYSIS COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Yuanhao Pang, Zhourui Xiao, Yanan Deng, Xueying Zhou, Yu Wang, Yali Yuan, Yun Zhang
Summary: Uniform cube-shaped copper nanoparticles and tiny nickel nanoparticles were obtained using the electrodeposition method, leading to the construction of a non-enzyme electrochemical glucose sensor with high catalytic activity. The bimetallic composite electrode showed improved catalytic performance due to the synergistic bimetallic catalysis effect. The electrode exhibited satisfactory linear response, low detection limit, good anti-interference ability, and reproducibility for glucose detection in practical samples.
Article
Biochemistry & Molecular Biology
Yi Kang, Xuelei Ren, Yejun Li, Zhiming Yu
Summary: In this study, a modified Ni and DLC-coated TiO2 nanotube composite electrode was prepared and evaluated as a glucose sensor. The results showed that the electrode exhibited superior electrochemical performance for glucose detection and had great potential for application in non-enzymatic glucose sensors.
Article
Engineering, Biomedical
Yingrui Deng, Xiaoting Zhang, Rui Li, Zhuo Li, Boguang Yang, Peng Shi, Honglu Zhang, Chunming Wang, Chunyi Wen, Gang Li, Liming Bian
Summary: This study investigates the efficacy of biofunctionalizing a hyaluronic acid hydrogel with a synthetic Wnt5a mimetic ligand (Foxy5 peptide) to promote the chondrogenesis of human mesenchymal stem cells (hMSCs). The conjugation of Foxy5 peptide in the hydrogels activates non-canonical Wnt signaling, leading to enhanced expression of chondrogenic markers and metabolic activities of encapsulated hMSCs. Furthermore, Foxy5 peptide inhibits hypertrophy of chondrogenically induced hMSCs through multiple signaling pathways. These findings provide valuable insights for the rational design of bio-inductive scaffolds in regenerative medicine.
Article
Gastroenterology & Hepatology
Chunyan Liu, Lintao Wang, Mengzhen Xu, Yajie Sun, Zhen Xing, Junfeng Zhang, Chunming Wang, Lei Dong
Summary: This study successfully transformed the spleen into a liver-like organ by directly reprogramming the splenic fibroblasts into hepatocytes. This method, which does not require cell or tissue transplantation, provides a potential therapeutic approach for the treatment of end-stage liver diseases.
Article
Biochemistry & Molecular Biology
Sen Zhu, Xuan Li, Bingrong Dang, Fen Wu, Chunming Wang, Changjun Lin
Summary: LBP protects skin cells from PM2.5-induced cytotoxicity by regulating the oxidative stress-ER stress-autophagy-apoptosis signaling axis.
Review
Pharmacology & Pharmacy
Ruoyu Mu, Senio Campos de Souza, Zhencheng Liao, Lei Dong, Chunming Wang
Summary: Despite advancements in skin repair therapies, chronic wounds like diabetic foot ulcers continue to be a global issue. Immune cells play crucial and diverse roles in the development and repair of skin tissue. Understanding and modulating the immune microenvironment can lead to comprehensive and perfect regeneration.
ADVANCED DRUG DELIVERY REVIEWS
(2022)
Article
Chemistry, Applied
Yurong Li, Shaocong Wang, Zhen Xing, Yiming Niu, Zhencheng Liao, Yang Lu, Junni Qiu, Junfeng Zhang, Chunming Wang, Lei Dong
Summary: Eliminating biofilms from infected tissue is a challenging task in treating chronic wounds. The study found that cationic polymers can disrupt biofilms and enhance bacterial antibiotic sensitivity. In a mouse wound healing model, cationic polymers effectively controlled infection and accelerated the healing process.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Analytical
Wenzhuo Chang, Yongxi Zhu, Yongjun Ma, Zhixiang Zheng, Chunming Wang
Summary: This article develops a silk-derived carbon material for the detection of chloramphenicol. This material proves to have excellent sensing performance and is successfully used in the detection of chloramphenicol in real samples.
CURRENT ANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Sen Zhu, Xuan Li, Fen Wu, Xinhui Cao, Kexin Gou, Chunming Wang, Changjun Lin
Summary: Research on the phototoxicity of blue light to the skin is increasing, and it has been found that blue light induces oxidative stress, ER stress, autophagy, and apoptosis in skin cells. Exogenous hydrogen sulfide (H2S) can protect the skin from blue light-induced damage by regulating these signaling pathways.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Sen Zhu, Xuan Li, Bingrong Dang, Fen Wu, Kexin Gou, Chunming Wang, Changjun Lin
Summary: This study investigated the therapeutic effects of exogenous hydrogen sulfide (H2S) in experimental models of retinal photodamage. The results showed that H2S could alleviate blue light-induced retinal oxidative stress, apoptosis, and degeneration, and inhibit the activation of ER stress CHOP apoptotic signaling. H2S also improved blue light-induced oxidative stress and damage, and alleviated apoptosis while increasing cell viability.
Article
Medicine, Research & Experimental
Ruoyu Mu, Zhe Zhang, Congwei Han, Yiming Niu, Zhen Xing, Zhencheng Liao, Jinzhi Xu, Ningyi Shao, Guokai Chen, Junfeng Zhang, Lei Dong, Chunming Wang
Summary: Nonhealing diabetic wounds can be effectively healed by training macrophages to mimic the reparative functions of tumor-associated macrophages (TAMs), which produce immunosuppressive and proliferative factors. These TAM-educated macrophages (TAMEMs) outperform other macrophage phenotypes in reducing inflammation, promoting angiogenesis, and activating fibroblasts. A nine-factor cocktail has also been developed to train human primary monocytes into TAMEMs, enabling the preparation of safer and autologous cells. This study demonstrates the potential of recapitulating TAMs' reparative activities in non-tumor cells for regenerative medicine.
EMBO MOLECULAR MEDICINE
(2023)
Review
Medicine, Research & Experimental
Zuohao Liu, Chunming Wang, Changjun Lin
Summary: Pyroptosis is a recently discovered programmed cell death mode caused by inflammasomes and Gasdermin family proteins. It leads to the release of inflammatory factors and triggers an inflammatory cascade response. Pyroptosis has different morphological features compared to other cell death modes and can be a potential cancer treatment strategy. However, there is still much unknown about its molecular mechanisms in pathogenicity and therapeutics, requiring further research.
Article
Zoology
Wen Guo, Mengna Wang, Haotian Li, Chunming Wang
Summary: A new species of nematode, Chromadorina communis sp. nov., is described in this study. Its characteristics include: medium-sized body, finely striated cuticle with homogeneous punctations, absence of ocelli, buccal cavity with three equal-sized, solid teeth, four cephalic setae, oval amphidial fovea between cephalic setae, curved spicules with tapered distal ends, simple boat-shaped gubernaculums, five or six cup-shaped precloacal supplements, and conical tail with a very short spinneret.
Article
Chemistry, Multidisciplinary
Xiaoyu Yin, Lintao Wang, Yiming Niu, Daping Xie, Qingwen Zhang, Jian Xiao, Lei Dong, Chunming Wang
Summary: This study discovered an oligosaccharide biomaterial (OG6) that stimulates specific expression of a chemokine in macrophages, leading to hair regeneration without inducing excessive inflammation. This finding opens up new possibilities for designing glycan-based therapeutic tools.
ADVANCED MATERIALS
(2023)
Article
Engineering, Biomedical
Daping Xie, Jiaxi Chen, Chonghao Chen, Yiming Niu, Lei Dong, Chunming Wang
Summary: The emerging applications of click chemistry have provided new possibilities for understanding cellular processes and designing therapeutic tools. This study focuses on the modification of neutrophils, which are known for short lives but play a crucial role in innate immune responses. A two-step strategy involving lipid fusion and click chemical reaction is studied to engineer neutrophil surfaces with carbohydrates. Among the modified neutrophils, those modified with mannose stimulate macrophage phagocytosis, suggesting a potential approach for anti-inflammatory therapies.
ADVANCED NANOBIOMED RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Shuaifei Ji, Mingchen Xiong, Huating Chen, Yiqiong Liu, Laixian Zhou, Yiyue Hong, Mengyang Wang, Chunming Wang, Xiaobing Fu, Xiaoyan Sun
Summary: The ageing process involves the decline from cellular dysfunction to organ degeneration, resulting in increased susceptibility to deteriorated disorders. However, rejuvenation techniques, such as cellular reprogramming and epigenetic regulation, have demonstrated that ageing can be reversed or delayed. This review discusses the factors influencing cell rejuvenation, the core mechanisms involved, and the latest advancements in rejuvenation strategies. These strategies, including cellular reprogramming, removal of senescence cells, metabolic manipulation, and immune rejuvenation, have potential applications in ageing-related disease treatment.
SIGNAL TRANSDUCTION AND TARGETED THERAPY
(2023)
Review
Immunology
Ruoyu Mu, Lei Dong, Chunming Wang
Summary: This article summarizes the latest trends in developing carbohydrate-containing adjuvants and discusses how the physicochemical characteristics of glycans affect their immunostimulatory functions. Additionally, potential technologies for addressing challenges in carbohydrate adjuvant design are explored from a translational perspective.
TRENDS IN IMMUNOLOGY
(2023)