How Does It Kill?: Understanding the Candidacidal Mechanism of Salivary Histatin 5

Activation of stress signalling pathways enhances tolerance of fungi to chemical fungicides and antifungal proteins

(2014) Brigitte M. E. Hayes et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interplay between Candida albicans and the Antimicrobial Peptide Armory

(2014) Marc Swidergall et al.   EUKARYOTIC CELL

Histatin 5-Spermidine Conjugates Have Enhanced Fungicidal Activity and Efficacy as a Topical Therapeutic for Oral Candidiasis

(2013) Swetha Tati et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Histatin 5 Resistance of Candida glabrata Can Be Reversed by Insertion of Candida albicans Polyamine Transporter-Encoding Genes DUR3 and DUR31

(2013) Swetha Tati et al.   PLoS One

Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis

(2012) Sumant Puri et al.   PLoS One

Msb2 Shedding Protects Candida albicans against Antimicrobial Peptides

(2012) Eva Szafranski-Schneider et al.   PLoS Pathogens

Release of Metal Ions from Orthodontic Appliances: An In Vitro Study

(2011) Marcin Mikulewicz et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Histatin 5 Uptake byCandida albicansUtilizes Polyamine Transporters Dur3 and Dur31 Proteins

(2011) Rohitashw Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of salivary histatin and the human cathelicidin LL-37 in wound healing and innate immunity

(2010) Menno J. Oudhoff et al.   BIOLOGICAL CHEMISTRY

Candida albicans  -Glucan Exposure Is Controlled by the Fungal CEK1-Mediated Mitogen-Activated Protein Kinase Pathway That Modulates Immune Responses Triggered through Dectin-1

(2010) M. Galan-Diez et al.   INFECTION AND IMMUNITY

Evidence of Intact Histatins in the in vivo Acquired Enamel Pellicle

(2010) W.L. Siqueira et al.   JOURNAL OF DENTAL RESEARCH

Influence of Histatin 5 onCandida albicansMitochondrial Protein Expression Assessed by Quantitative Mass Spectrometry

(2010) Tomoko Komatsu et al.   JOURNAL OF PROTEOME RESEARCH

Salivary histatin 5 internalization by translocation, but not endocytosis, is required for fungicidal activity in Candida albicans

(2010) Woong Sik Jang et al.   MOLECULAR MICROBIOLOGY

Concentration and fate of histatins and acidic proline-rich proteins in the oral environment

(2009) Melanie Campese et al.   ARCHIVES OF ORAL BIOLOGY

A plausible role of salivary copper in antimicrobial activity of histatin-5—Metal binding and oxidative activity of its copper complex

(2009) William M. Tay et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

BAR Domain Proteins Rvs161 and Rvs167 Contribute to Candida albicans Endocytosis, Morphogenesis, and Virulence

(2009) L. M. Douglas et al.   INFECTION AND IMMUNITY

A Novel Immune Evasion Strategy of Candida albicans: Proteolytic Cleavage of a Salivary Antimicrobial Peptide

(2009) Timothy F. Meiller et al.   PLoS One

Histatins are the major wound-closure stimulating factors in human saliva as identified in a cell culture assay

(2008) Menno J. Oudhoff et al.   FASEB JOURNAL

In vitro reactive oxygen species production by histatins and copper(I,II)

(2008) Eric A. Houghton et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Uptake of the antifungal cationic peptide Histatin 5 byCandida albicansSsa2p requires binding to non-conventional sites within the ATPase domain

(2008) Jianing N. Sun et al.   MOLECULAR MICROBIOLOGY

The Antimicrobial Peptide Histatin-5 Causes a Spatially Restricted Disruption on the Candida albicans Surface, Allowing Rapid Entry of the Peptide into the Cytoplasm

(2008) A. Brian Mochon et al.   PLoS Pathogens

Nickel, Chromium and Iron Levels in the Saliva of Patients with Simulated Fixed Orthodontic Appliances

(2007) Rodrigo Matos de Souza et al.   ANGLE ORTHODONTIST