Journal
ESSAYS IN BIOCHEMISTRY: CHRONOBIOLOGY
Volume 49, Issue -, Pages 103-117Publisher
PORTLAND PRESS LTD
DOI: 10.1042/BSE0490103
Keywords
-
Categories
Funding
- NIGMS NIH HHS [GM078993, R01 GM078993] Funding Source: Medline
- NIMH NIH HHS [MH63104, R01 MH063104] Funding Source: Medline
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM078993] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF MENTAL HEALTH [R01MH063104] Funding Source: NIH RePORTER
Ask authors/readers for more resources
In vitro assays have localized circadian pacemakers to individual cells, revealed genetic determinants of rhythm generation, identified molecular players in cell cell synchronization and determined physiological events regulated by circadian clocks. Although they allow strict control of experimental conditions and reduce the number of variables compared with in vivo studies, they also lack many of the conditions in which cellular circadian oscillators normally function. The present review highlights methods to study circadian timing in cultured mammalian cells and how they have shaped the hypothesis that all cells are capable of circadian rhythmicity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available