Article
Agriculture, Dairy & Animal Science
Kajsa Gustafsson, Amos J. Tatz, Roee Dahan, Wiessam Abu Ahmad, Malka Britzi, Gila A. Sutton, Gal Kelmer
Summary: The study aimed to investigate the safety and pharmacokinetics of trimethoprim-sulphadiazine administered via intravenous regional limb perfusion (IVRLP) into the cephalic vein. However, severe vasculitis in some horses led to low concentrations of trimethoprim-sulphadiazine in synovial fluid.
Article
Veterinary Sciences
Eva Depuydt, Sarah Y. Broeckx, Lore Van Hecke, Koen Chiers, Leen Van Brantegem, Hans van Schie, Charlotte Beerts, Jan H. Spaas, Frederik Pille, Ann Martens
Summary: The study showed that equine allogeneic tenogenic primed mesenchymal stem cells were well-tolerated and may be effective for the management of tendon injuries.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Veterinary Sciences
Franziska C. Wagner, Sven Reese, Kerstin Gerlach, Peter Bottcher, Christoph K. W. Mulling
Summary: The study successfully developed a novel cryo-clamp for repetitive cyclic tensile testing of equine tendons, and validated a biplanar high-speed fluoroscopy system for tracking tendon movement. The precision of the tracking system and stability of the clamping technique were verified, highlighting the importance of repetitive cyclical testing for understanding tendon behavior under load in equine superficial digital flexor tendons.
BMC VETERINARY RESEARCH
(2021)
Article
Veterinary Sciences
Molly O'Brien, Jonathan P. Mochel, Kevin Kersh, Chong Wang, Jarrod Troy
Summary: This study aimed to investigate the pharmacokinetics and local complications of the NSAID phenylbutazone (PBZ) used for intravenous regional limb perfusion (IVRLP) in horses. The results showed that IVRLP with PBZ at a dose of 2.2 mg/kg did not provide any advantage compared to systemic PBZ administration, and the local complications were similar to placebo-IVRLP.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Veterinary Sciences
Rachel O. Salz, Christopher R. B. Elliott, Tomas Zuffa, Euan D. Bennet, Benjamin J. Ahern
Summary: Treatment with autologous bone marrow-derived mesenchymal stem cells (BM-MSCs) is associated with an increased likelihood of returning to racing and completing five or more races post-injury, compared to racehorses managed with a controlled exercise rehabilitation program (CERP) alone. There is no observed increased likelihood of return to racing or completing five or more races associated with treatment with allogenic adipose-derived mesenchymal stem cells (A-MSCs) compared to CERP alone.
EQUINE VETERINARY JOURNAL
(2023)
Review
Veterinary Sciences
Anna Ehrle, Svenja Lilge, Peter D. Clegg, Thomas W. Maddox
Summary: Flexor tendon injuries are a major cause of lameness in performance horses, impacting equine welfare and the horse industry. Recent research focuses on identifying subclinical tendon damage for prevention and better treatment outcomes. New imaging technologies like elastography show potential to change the clinical approach to equine flexor tendon imaging.
VETERINARY JOURNAL
(2021)
Article
Agriculture, Dairy & Animal Science
Valentina Secchi, Gerolamo Masala, Andrea Corda, Francesca Corda, Enrica Potop, Alicia Barbero Fernandez, Maria Luisa Pinna Parpaglia, Eraldo Sanna Passino
Summary: The study demonstrated the repeatability and reproducibility of manual measurements of elastograms obtained from injured superficial digital flexor tendons of horses. Despite subjectivity, manual measurements proved to be repeatable and reproducible, with results matching those obtained with external software. The manual modality was validated as a viable method for analyzing images obtained with strain elastography through comparison with external software and standardization of image analysis.
Article
Biochemistry & Molecular Biology
Michael J. Mienaltowski, Mitchell Callahan, Nicole L. Gonzales, Angelique Wong
Summary: This study investigated the effects of vitamin C on the tenogenic properties of equine superficial digital flexor tendon cells. It was found that vitamin C had anti-inflammatory effects, alleviated degenerative pathways, and increased collagen content in tendon cells. However, the cytoprotective effect of vitamin C varied between different types of tendon cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Veterinary Sciences
Luca Melotti, Anna Carolo, Noha Elshazly, Filippo Boesso, Laura Da Dalt, Gianfranco Gabai, Anna Perazzi, Ilaria Iacopetti, Marco Patruno
Summary: This case report describes a successful treatment of chronic tendonitis in a show jumping horse using repeated intralesional injections of autologous adipose-derived mesenchymal stem cells (AD-MSCs) and autologous platelet-rich plasma (PRP). The treatment led to the reduction of lameness, swelling, and pain, and the horse was able to resume competing at its previous level.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Veterinary Sciences
Andrew Frederick Rich, Emanuele Ricci, Sophie Gates, Guy Joseph Hinnigan, Kathryn Rose Owen
Summary: A 20-year-old British Warmblood gelding presented with worsening lameness in the right forelimb, which did not improve following an eight-week rehabilitation programme, resulting in euthanasia. Histopathological examination revealed an intratendinous fibroma, a rare neoplasm in horses and the first case reported in an adult horse and in the SDFT.
JOURNAL OF EQUINE VETERINARY SCIENCE
(2021)
Article
Veterinary Sciences
Franziska C. Wagner, Kerstin Gerlach, Sandra M. Geiger, Claudia Gittel, Peter Bottcher, Christoph K. W. Mulling
Summary: This study utilized biplanar high-speed fluoroscopic kinematography to investigate tendon strain in ponies, finding that the strain in injured tendons changed during different gaits, with less load on the injured tendon during walking.
VETERINARY SCIENCES
(2021)
Article
Veterinary Sciences
Angela M. Gaesser, Claire Underwood, Renata L. Linardi, Kayla M. Even, Virginia B. Reef, Snehal S. Shetye, Robert L. Mauck, William J. King, Julie B. Engiles, Kyla F. Ortved
Summary: This study evaluated the effects of autologous protein solution (APS) on tendon healing in equine superficial digital flexor (SDF) tendonitis model, showing that APS treatment may improve healing processes, though no significant differences in structural or biomechanical characteristics were observed at 12 weeks.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Veterinary Sciences
Mai Iimori, Norihisa Tamura, Kazuhiro Seki, Yoshinori Kasashima
Summary: The study found that there is a close relationship between an increased cross-sectional area or edema in the subcutaneous tissue and the subsequent onset of severe SDFT injury.
JOURNAL OF VETERINARY MEDICAL SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Gail L. Huckins, Richard R. Sim, Barry Hartup
Summary: Foot and limb infections are common issues in captive cranes, and traditional antibiotic therapy can be unrewarding. This study reports the successful treatment of such infections in three crane species using regional limb perfusion of intravenous antibiotics in combination with systemic antibiotics. Clinical signs of infection resolved within 10-40 days following treatment, and no side effects were observed. This is the first report of regional limb perfusion in cranes and the first report of intravenous regional limb perfusion in a wing of an avian species.
Review
Veterinary Sciences
Claire O'Brien, Neil Marr, Chavaunne Thorpe
Summary: This review discusses the biomechanical and biothermal effects of strain on the SDFT, as well as the impact of age-related alterations on injury risk. It emphasizes the importance of timely detection and adjustment of training protocols to prevent SDFT injuries.
EQUINE VETERINARY JOURNAL
(2021)
Editorial Material
Veterinary Sciences
A. Sole, B. Ahern
EQUINE VETERINARY EDUCATION
(2021)
Article
Veterinary Sciences
Amy Norvall, Mathieu Spriet, Pablo Espinosa, Gerard Arino-Estrada, Brian G. Murphy, Scott A. Katzman, Larry D. Galuppo
Summary: This study found increased F-18-NaF uptake at the ChSL attachment in horses, which is commonly associated with other lesions but may also be the main abnormality. ChSL enthesopathy was a primary lesion in some cases, with no significant association with other abnormalities. CT imaging plays an important role in identifying abnormalities at the ChSL attachment.
EQUINE VETERINARY JOURNAL
(2021)
Article
Veterinary Sciences
Jennifer L. Willcox, Mathieu Spriet, Allison L. Zwingenberger, Kathryn L. Phillips, Jenna H. Burton, Katherine A. Skorupski, Katherine S. Hansen, Verena K. Affolter, Kevin D. Woolard, David Beylin, Michelle A. Giuffrida
Summary: In this study, PET/CT imaging was used for dogs with oral malignant melanoma, showing high sensitivity but caution needed for specificity improvement. PET techniques demonstrated 100% sensitivity, with SUV evaluation increasing specificity. Careful parameter and threshold selection is critical to ensure PET specificity in diagnosing canine OMM.
VETERINARY AND COMPARATIVE ONCOLOGY
(2021)
Article
Veterinary Sciences
Pablo Espinosa-Mur, Kathryn L. Phillips, Larry D. Galuppo, Anthony DeRouen, Philippe Benoit, Eleanor Anderson, Karen Shaw, Sarah Puchalski, Duncan Peters, Philip H. Kass, Mathieu Spriet
Summary: This study found that there was a range of interpretation of radiographic findings of the caudal cervical region, suggesting that osteoarthritis in this area is not rare in performing sound Warmblood jumpers. The study indicated that osteoarthritis in the caudal cervical region may have low clinical significance.
EQUINE VETERINARY JOURNAL
(2021)
Article
Veterinary Sciences
Rebecca A. Hersh-Boyle, Po-Yen Chou, Amy S. Kapatkin, Mathieu Spriet, Barbro Filliquist, Tanya C. Garcia, Denis J. Marcellin-Little
Summary: The study evaluated the diagnostic value of still images of needle arthroscopy (SNAR), still images of traditional arthroscopy (STAR), and computed tomography (CT) in diagnosing medial coronoid process (MCP) pathology. Still images of NAR, STAR, and CT were found to have similar diagnostic value in identifying MCP fissures, while still images of TAR were superior in identifying MCP fragments.
VETERINARY SURGERY
(2021)
Article
Veterinary Sciences
Ehren McLarty, Mathieu Spriet, David Beylin, Po-Yen Chou, Barbro Filliquist, Denis J. Marcellin-Little, Amy S. Kapatkin
Summary: This study suggests that PET imaging can improve the detection of lesions and the clinical significance of CT findings in dogs with elbow pain, with a stronger correlation observed between PET scores and clinical grades compared to CT scores.
VETERINARY RADIOLOGY & ULTRASOUND
(2021)
Article
Veterinary Sciences
Sabrina Wilson, Mathieu Spriet, Pablo Espinosa Mur, Sergey Anishchenko, David Beylin, Scott Katzman, Larry Galuppo
Summary: Lesions of the deep digital flexor tendon in horses can be detected using F-18-FDG PET, which is more closely aligned with arterial contrast CT and T2-weighted/STIR MRI in identifying active lesions. PET provides valuable information regarding metabolic activity and can be a useful tool for diagnosing DDFT lesions in horses.
VETERINARY RADIOLOGY & ULTRASOUND
(2021)
Article
Veterinary Sciences
J. R. Fletcher, K. Y. Yuen, A. J. Stewart, A. C. Young, J. S. Gibson, O. A. James, C. E. Medina-Torres, B. M. Forde, A. Sole-Guitart
Summary: Chronic oroantral fistulae (OAF) with secondary sinusitis can occur in horses following repulsion of cheek teeth. This case report describes the successful treatment of a complicated OAF with concurrent MDR Escherichia coli infection using various therapeutic strategies. Whole-genome sequencing may be beneficial in guiding antimicrobial selection for MDR or XDR infections in the future.
AUSTRALIAN VETERINARY JOURNAL
(2022)
Article
Veterinary Sciences
Jannah Pye, Mathieu Spriet, Penny Dow, Scott Katzman, Brian G. Murphy
Summary: This study describes the clinical, imaging, gross, and histopathological abnormalities associated with osteochondral necrosis of the femoral condyles in foals, and identifies features suggestive of a common pathogenesis.
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION
(2022)
Article
Veterinary Sciences
H. Nagel, H. Lang, A. Sole Guitart, N. Lean, R. Allavena, C. Sprohnle-Barrera, A. Young
Summary: This case series describes two horses diagnosed with aggressive submural neoplasia, specifically an anaplastic sarcoma and a squamous cell carcinoma. The study utilized various imaging techniques and histopathology with immunohistochemistry to characterize these neoplasms. The main clinical feature in these cases was chronic reoccurring lameness, accompanied by expansile osteolytic changes and adjacent hoof wall abnormalities. Advanced imaging can aid in differential diagnosis, but histopathological examination is still necessary for definitive diagnosis.
AUSTRALIAN VETERINARY JOURNAL
(2022)
Article
Agriculture, Dairy & Animal Science
Hyungsuk Kang, Rebeka R. Zsoldos, Jazmine E. Skinner, John B. Gaughan, Vincent A. Mellor, Albert Sole-Guitart
Summary: This study investigated the relationship between core body temperature and temperature readings obtained using PTSM implanted in different muscles during and post-exercise. It found that PTSM technology provided a practical and safe means of measuring body temperature in horses, but the accuracy of the temperature readings varied depending on the implantation site. The pectoral muscle had the most consistent relationship with core body temperature and showed the best potential for monitoring body temperature in horses without human intervention.
Article
Veterinary Sciences
Natasha E. Lean, Albert Sole-Guitart, Benjamin J. Ahern
Summary: This study investigated the feasibility and clinical experience of performing laryngeal tie-forward (LTF) in standing horses with or without intermittent dorsal displacement of the soft palate (iDDSP). The results showed that standing LTF was well tolerated and completed in all horses, and had a positive effect on the position of the larynx and the resolution of iDDSP.
VETERINARY SURGERY
(2023)
Article
Veterinary Sciences
Shaun Pratt, Tamsin S. Barnes, Nicholas Cowling, Karla de Klerk, Joanne Rainger, Albert Sole-Guitart, Solomon Woldeyohannes, Wendy Goodwin
Summary: This study compared the invasive and non-invasive methods of measuring blood pressure in healthy horses using the Bionet BM7Vet and found that the device showed some inaccuracies in measuring blood pressure.
VETERINARY SCIENCES
(2022)
Article
Veterinary Sciences
Pablo Espinosa-Mur, Mathieu Spriet, Marcos Perez Nogues, Thomas Cullen, Larry D. Galuppo
Summary: Surgical treatment for osteoarthritis of the talocalcaneal joint in a 16-year-old Quarter Horse mare led to initial complications but ultimately resulted in complete fusion of the joint and resolution of lameness after 48 months of rehabilitation.
CANADIAN VETERINARY JOURNAL-REVUE VETERINAIRE CANADIENNE
(2021)
Article
Veterinary Sciences
Nicholas Cowling, Solomon Woldeyohannes, Albert Sole Guitart, Wendy Goodwin
Summary: The study aimed to identify the muscle belly that provided the highest percentage of successful StO(2) readings and the highest mean StO(2) values in horses. The sartorius muscle was found to be the preferred muscle for StO(2) measurement, while clipping and cleaning of the probe placement site were recommended. Administering medetomidine was associated with lower StO(2) values in all muscles.
VETERINARY SCIENCES
(2021)