Article
Agriculture, Dairy & Animal Science
Anna Marei Grages, Nicole Verhaar, Christiane Pfarrer, Gerhard Breves, Marion Burmester, Stephan Neudeck, Sabine Kastner
Summary: This study compared two experimental models, low flow and no flow, to characterize the development of intestinal injury in horses. The results showed that the no flow model produced more consistent intestinal damage compared to the low flow model.
Article
Agriculture, Dairy & Animal Science
Patricia Ruiz-Lopez, Charlotte Cuypers, Stijn Schauvliege
Summary: This retrospective study evaluated the effects of adding xylazine infusion to anesthesia maintenance in horses undergoing colic surgery. The results showed that the group receiving xylazine infusion had lower heart rate, hematocrit, ketamine requirements, and shorter days to discharge compared to the group without xylazine infusion. However, the time to sternal recumbency and time to first attempt were longer in the xylazine group. Xylazine infusion may provide stable anesthesia and faster recovery in colic patients.
Article
Veterinary Sciences
Franziska Dengler, Felix Sternberg, Marei Grages, Sabine B. R. Kaestner, Nicole Verhaar
Summary: This study investigated the adaptation mechanisms in equine small intestinal ischemia reperfusion injury (IRI) and found that HIF1 alpha and mitophagy are activated in response to IRI, indicating their potential therapeutic role in promoting cellular survival.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Catherine Torcivia, Sue McDonnell
Summary: Researchers have compiled a comprehensive ethogram of behaviors associated with equine physical discomfort, aiming to improve recognition and understanding of pain management in horses. The ethogram provides clarity and communication regarding equine discomfort and pain, with the ultimate goal of enhancing horse welfare.
Article
Pharmacology & Pharmacy
Louise M. Hesketh, Markus B. Sikkel, Laura Mahoney-Sanchez, Francesca Mazzacuva, Rasheda A. Chowdhury, Konstantinos N. Tzortzis, Jahn Firth, James Winter, Kenneth T. MacLeod, Stefan Ogrodzinski, Catherine D. E. Wilder, Laurence H. Patterson, Nicholas S. Peters, Michael J. Curtis
Summary: OCT2013 is an inactive prodrug that can be bio-reduced locally in ischemic myocardium to lidocaine, acting as an ischemia-activated and ischemia-selective antiarrhythmic drug with a large therapeutic index, mimicking lidocaine's benefits without adverse reactions.
BRITISH JOURNAL OF PHARMACOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Nicole Verhaar, Susanne Hoppe, Anna Marei Grages, Kathrin Hansen, Stephan Neudeck, Sabine Kaestner, Gemma Mazzuoli-Weber
Summary: The aim of this study was to determine the effect of dexmedetomidine on small intestinal contractility during different phases of ischaemia. The addition of dexmedetomidine caused a decrease in the spontaneous contractile activity of the circular smooth muscle (CSM), but an increase in that of the longitudinal smooth muscle (LSM), which was not mediated by the enteric nervous system. These results may indicate a stimulatory effect of dexmedetomidine on small intestinal contractility.
Review
Biochemistry & Molecular Biology
Elise Pretzsch, Hanno Niess, Najib Ben Khaled, Florian Boesch, Markus Guba, Jens Werner, Martin Angele, Irshad H. Chaudry
Summary: Hepatic ischemia-reperfusion injury is a major challenge in liver surgery and transplantation, and is associated with tumor growth and recurrence risk. Current therapeutic strategies have not shown protective effects in a clinical setting.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Veterinary Sciences
Nicole Verhaar, Gerhard Breves, Marion Hewicker-Trautwein, Christiane Pfarrer, Karl Rohn, Marion Burmester, Nadine Schnepel, Stephan Neudeck, Lara Twele, Sabine Kaestner
Summary: IPoC reduced intestinal microperfusion and villus denudation, as well as decreased mucosal-to-serosal flux rates in horses with small intestinal ischaemia, suggesting a potential protective effect on ischaemia reperfusion injury.
EQUINE VETERINARY JOURNAL
(2022)
Article
Agriculture, Dairy & Animal Science
Tamzin Furtado, Liane Preshaw, Jo Hockenhull, Jennifer Wathan, Janet Douglas, Sue Horseman, Rebecca Smith, Danica Pollard, Gina Pinchbeck, Jan Rogers, Carol Hall
Summary: In equestrian sports, the main welfare challenge arises from conflicts between competition demands and the basic needs of horses, with a lack of focus on horses' psychological needs. Improving general management and training of horses may have more impact than improving competition practices. Stakeholders favor the use of "quality of life" over "welfare."
Article
Agriculture, Dairy & Animal Science
Sharon Tirosh-Levy, Amir Steinman
Summary: Equine encephalosis (EE) is a febrile disease of horses caused by EE virus (EEV) and transmitted by Culicoides midges. The virus was first isolated from a horse in South Africa in 1967 and has since spread to other regions. Although EEV does not cause severe clinical disease, its spread may indicate the potential spread of more pathogenic viruses. This review provides an overview of the structure, pathogenesis, clinical significance, and epidemiology of EEV.
Article
Business
Oana-Daniela Lupoae, Violetta Wilk, Riana Iren Radu
Summary: This paper explores sustainable entrepreneurship in the equine industry through a qualitative research approach. The study shows that women with less than ten years of entrepreneurial experience are more inclined towards sustainability. Entrepreneurs in the horse sector need to be aware of the potential and support each other to strengthen their self-efficacy.
JOURNAL OF BUSINESS RESEARCH
(2024)
Review
Veterinary Sciences
Linda Greening, Sebastian McBride
Summary: This review article focuses on equine sleep, aiming to consolidate current knowledge on normal sleep in horses, measurement methods, the relationship between sleep changes and welfare, and the primary factors affecting equine sleep. It also discusses gaps in current knowledge and sets the direction for future research to improve equine performance and welfare.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Review
Agriculture, Dairy & Animal Science
Katherine Jennifer Kelly, Laurie Anne McDuffee, Kimberly Mears
Summary: Human-horse interactions (HHIs) are diverse and significant in the equine industry, with a focus on the welfare of horses - both mentally and physically. Current understanding of the horse's mental state during interactions is limited, with more research needed to evaluate and improve the overall welfare of horses.
Article
Genetics & Heredity
Sichong Peng, Rebecca Bellone, Jessica L. Petersen, Theodore S. Kalbfleisch, Carrie J. Finno
Summary: ATAC-seq is a popular method to assess genome-wide chromatin accessibility, and the extraction and storage of nuclei from horse tissues can impact the experimental results, with tissue type dictating the optimal approach for ATAC-seq experiments.
FRONTIERS IN GENETICS
(2021)
Review
Biochemistry & Molecular Biology
Richi Nakatake, Mareike Schulz, Christina Kalvelage, Carina Benstoem, Rene H. Tolba
Summary: The study focused on inducible nitric oxide synthase (iNOS) as an early inflammatory response to hepatic ischaemia reperfusion injury (HIRI) and found that iNOS was upregulated in almost all HIRIs, with no direct associations of endothelial nitric oxide synthase (eNOS) or nitric oxide (NO) with iNOS.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Physiology
Walter Arnold, Christoph Beiglboeck, Marion Burmester, Maria Guschlbauer, Astrid Lengauer, Bernd Schroeder, Mirja Wilkens, Gerhard Breves
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
(2015)
Correction
Cardiac & Cardiovascular Systems
Thorsten Wittwer, Parwis Rahmanian, Yeong-Hoon Choi, Mohamed Zeriouh, Samira Karavidic, Klaus Neef, Astrid Christmann, Tanja Piatkowski, Anke Schnapper, Matthias Ochs, Christian Muehlfeld, Anja Sterner-Kock, Maria Guschlbauer, Florian Hofmaier, Alexandra C. Maul, Thorsten Wahlers
JOURNAL OF CARDIOTHORACIC SURGERY
(2015)
Article
Multidisciplinary Sciences
Maria Guschlbauer, Alexandra C. Maul, Xiaowei Yan, Holger Herff, Thorsten Annecke, Anja Sterner-Kock, Bernd W. Boettiger, Daniel C. Schroeder
Article
Agriculture, Dairy & Animal Science
Anja Sterner-Kock, Wolfram Haider, Flavio Sacchini, Anne Liljander, Jochen Meens, Jane Poole, Maria Guschlbauer, Martin Heller, Jan Naessens, Joerg Jores
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2016)
Article
Anatomy & Morphology
Anke Schnapper, Astrid Christmann, Lars Knudsen, Parwis Rahmanian, Yeong-Noon Choi, Mohamed Zeriouh, Samira Karavidic, Klaus Neef, Anja Sterner-Kock, Maria Guschlbauer, Florian Hofmaier, Alexandra C. Maul, Thorsten Wittwer, Thorsten Wahlers, Christian Muehlfeld, Matthias Ochs
JOURNAL OF ANATOMY
(2018)
Article
Surgery
Carolyn Weber, Stefanie Reinhardt, Kaveh Eghbalzadeh, Max Wacker, Maria Guschlbauer, Alexandra Maul, Anja Sterner-Kock, Thorsten Wahlers, Jens Wippermann, Max Scherner
JOURNAL OF VASCULAR SURGERY
(2018)
Article
Endocrinology & Metabolism
Philipp Schommers, Anna Thurau, Insa Bultmann-Mellin, Maria Guschlbauer, Andreas R. Klatt, Jan Rozman, Martin Klingenspor, Martin Hrabe de Angelis, Jens Alber, Dirk Gruendemann, Anja Sterner-Kock, Rudolf J. Wiesner
MOLECULAR METABOLISM
(2017)
Article
Anesthesiology
Daniel C. Schroeder, Alexandra C. Maul, Esther Mahabir, Isabell Koxholt, Xiaowei Yan, Stephan A. Padosch, Holger Herff, Insa Bultmann-Mellin, Anja Sterner-Kock, Thorsten Annecke, Tim Hucho, Bernd W. Boettiger, Maria Guschlbauer
BMC ANESTHESIOLOGY
(2018)
Article
Veterinary Sciences
Maria . Guschlbauer, Karsten Feige, Florian Geburek, Susanne Hoppe, Klaus Hopster, Marcus J. Proepsting, Korinna Huber
AMERICAN JOURNAL OF VETERINARY RESEARCH
(2011)
Article
Biochemistry & Molecular Biology
Anja Cehak, Mirja R. Wilkens, Maria Guschlbauer, Nina Mrochen, Bernd Schroeder, Karsten Feige, Gerhard Breves
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2012)
Article
Biochemistry & Molecular Biology
Maria Guschlbauer, Stefanie Klinger, Marion Burmester, Jana Horn, Sabine E. Kulling, Gerhard Breves
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2013)
Article
Surgery
Maximilian Scherner, Stefanie Reutter, Dieter Klemm, Anja Sterner-Kock, Maria Guschlbauer, Thomas Richter, Georg Langebartels, Navid Madershahian, Thorsten Wahlers, Jens Wippermann
JOURNAL OF SURGICAL RESEARCH
(2014)
Article
Veterinary Sciences
Frauke Uhlendorf, Maria Guschlbauer, Susanne Hoppe, Korinna Huber, Karsten Feige
Article
Multidisciplinary Sciences
Daniel C. Schroeder, Maria Guschlbauer, Alexandra C. Maul, Daniel A. Cremer, Ingrid Becker, David de la Puente Bethencourt, Peter Paal, Stephan A. Padosch, Wolfgang A. Wetsch, Thorsten Annecke, Bernd W. Boettiger, Anja Sterner-Kock, Holger Herff
Article
Veterinary Sciences
Manuela Kuhn, Maria Guschlbauer, Karsten Feige, Michael Schluesener, Kai Bester, Martin Beyerbach, Gerhard Breves
BERLINER UND MUNCHENER TIERARZTLICHE WOCHENSCHRIFT
(2012)