☆ 4.2 Article

Giant subcortical heterotopia involving the temporo-parieto-occipital region: A challenging cause of drug-resistant epilepsy

EPILEPSY RESEARCH (2009)

Journal

EPILEPSY RESEARCH

Volume 87, Issue 1, Pages 88-94

Publisher

ELSEVIER SCIENCE BV

DOI: 10.1016/j.eplepsyres.2009.06.006

Keywords

Subcortical heterotopia; Infancy; Surgery; Drug-resistant epilepsy; Cognitive delay

Categories

Clinical Neurology

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Abstract

The clinical, radiological, neurophysiological and neuropsychological findings of three patients with giant subcortical heterotopia are reported. All patients experienced psychomotor and behaviour improvement after surgery. Two subjects are seizure-free after complete excision of the heterotopia; the third patient significantly improved following subtotal removal (Engel's class II). Patients affected by giant subcortical heterotopias can have a favourable prognosis after the surgical removal of the malformation, even following long-lasting epilepsy. (C) 2009 Elsevier B.V. All rights reserved.

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