Carisbamate acutely suppresses spasms in a rat model of symptomatic infantile spasms

DEVELOPMENTAL PHARMACOLOGY: NEONATES ARE NOT JUST SMALL ADULTS…

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Antiepileptic and Antiepileptogenic Performance of Carisbamate after Head Injury in the Rat: Blind and Randomized Studies

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Carisbamate in essential tremor: Brief report of a proof of concept study

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Targeted loss of Arx results in a developmental epilepsy mouse model and recapitulates the human phenotype in heterozygous females

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Investigation of the effects of the novel anticonvulsant compound carisbamate (RWJ-333369) on rat piriform cortical neurones in vitro

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Pharmacokinetics of carisbamate (RWJ-333369) in healthy Japanese and Western subjects

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A Triplet Repeat Expansion Genetic Mouse Model of Infantile Spasms Syndrome, Arx(GCG)10+7, with Interneuronopathy, Spasms in Infancy, Persistent Seizures, and Adult Cognitive and Behavioral Impairment

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(2009) Carl E. Stafstrom   Epilepsy Currents

A new potential AED, carisbamate, substantially reduces spontaneous motor seizures in rats with kainate-induced epilepsy

(2008) Heidi L. Grabenstatter et al.   EPILEPSIA

The novel antiepileptic drug carisbamate (RWJ 333369) is effective in inhibiting spontaneous recurrent seizure discharges and blocking sustained repetitive firing in cultured hippocampal neurons

(2008) Laxmikant S. Deshpande et al.   EPILEPSY RESEARCH

Pharmacokinetics, safety, and tolerability of the new antiepileptic carisbamate in the elderly

(2008) Rene Levy et al.   EPILEPSY RESEARCH

Carisbamate, a novel neuromodulator, inhibits voltage-gated sodium channels and action potential firing of rat hippocampal neurons

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Randomized, controlled, dose-ranging trial of carisbamate for partial-onset seizures

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Effects of Carisbamate (RWJ-333369) in Two Models of Genetically Determined Generalized Epilepsy, the GAERS and the Audiogenic Wistar AS

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A new animal model of infantile spasms with unprovoked persistent seizures

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