Review
Medicine, General & Internal
Jermaine M. Dambi, Frances M. Cowan, Faith Martin, Sharon Sibanda, Victoria Simms, Nicola Willis, Sarah Bernays, Webster Mavhu
Summary: This article discusses the common mental disorders among HIV patients in Sub-Saharan Africa and the need to integrate mental healthcare into routine HIV care. The article proposes a review method to assess the mental health of young HIV patients in Sub-Saharan Africa and evaluate the psychometric properties of positive psychological outcome measures.
Review
Clinical Neurology
Carmen Barba, Sabrina Giometto, Ersilia Lucenteforte, Simona Pellacani, Giulia Matta, Alessandra Bettiol, Sara Minghetti, Lavinia Falorni, Federico Melani, Gianpiero Di Giacomo, Flavio Giordano, Salvatore De Masi, Renzo Guerrini
Summary: The efficacy of temporal lobe epilepsy (TLE) surgery varies between children and adults, with higher seizure freedom rates observed in children. Histopathology and surgical approach have an impact on seizure outcome, with age being an important variable.
Article
Critical Care Medicine
James T. Neill, Ian Goch, Arron Sullivan, Megan Simons
Summary: This study examined the role of therapeutic camp experiences in the recovery journeys of children and adolescents who had experienced burn injury. The overwhelming majority of participants reported a positive experience of camp and recommended it to other youth with burns. The strengths of the camp experience included fun activities, social relatedness, camp setting, and acceptance. The impacts of the camp on youth campers included normalizing, social support, psychological recovery, and increased confidence.
Review
Oncology
Clarissa E. Schilstra, Joanna E. Fardell, Mary A. Burns, Sarah J. Ellis, Antoinette C. Anazodo, Toby N. Trahair, Ursula M. Sansom-Daly
Summary: This systematic review examined 37 publications from 2000 to 2021 regarding social functioning in adolescent and young adult cancer survivors. The definition and measures of social functioning varied across studies, as did the factors associated with it. Factors commonly linked to decreased social functioning included treatment status, physical functioning, depression, negative body image, social comparisons, and cancer-related stigma, while social support and quality of care were associated with increased social functioning.
Review
Oncology
Atsushi Makimoto
Summary: Due to their rarity, there is limited understanding of rhabdomyosarcomas (RMS) in adolescents and young adults (AYA), resulting in poor treatment outcomes. This review aims to integrate new developments with existing evidence to explore factors and potential solutions in RMS in AYA.
Article
Clinical Neurology
Klajdi Puka, Monika Jones, Gary W. Mathern
Summary: Children with HME who undergo hemispherectomy show delayed language milestones and often need long-term language and literacy support. Significant correlations were found between better cognitive and language outcomes and undergoing a right hemisphere resection or having an older age at epilepsy onset.
Article
Clinical Neurology
Carolina Ferreira-Atuesta, Jane de Tisi, Andrew W. McEvoy, Anna Miserocchi, Jean Khoury, Ruta Yardi, Deborah T. Vegh, James Butler, Hamin J. Lee, Victoria Deli-Peri, Yi Yao, Feng-Peng Wang, Xiao-Bin Zhang, Lubna Shakhatreh, Pakeeran Siriratnam, Andrew Neal, Arjune Sen, Maggie Tristram, Elizabeth Varghese, Wendy Biney, William P. Gray, Ana Rita Peralta, Alexandre Rainha-Campos, Antonio J. C. Goncalves-Ferreira, Jose Pimentel, Juan Fernando Arias, Samuel Terman, Robert Terziev, Herm J. Lamberink, Kees P. J. Braun, Willem M. Otte, Fergus J. Rugg-Gunn, Walter Gonzalez, Carla Bentes, Khalid Hamandi, Terence J. O'Brien, Piero Perucca, Chen Yao, Richard J. Burman, Lara Jehi, John S. Duncan, Josemir W. Sander, Matthias Koepp, Marian Galovic
Summary: More than half of adults with epilepsy undergoing resective epilepsy surgery achieve long-term seizure freedom and might consider withdrawing antiseizure medications. Predictive models were developed and validated to identify factors contributing to seizure recurrence after starting postoperative antiseizure medication withdrawal.
Article
Multidisciplinary Sciences
Blanca Dolz-del-Castellar, Jesus Oliver
Summary: The study found relationships between family functioning, differentiation of self, and trait anxiety, with differences in differentiation of self and trait anxiety based on gender. Family functioning predicted the level of differentiation of self, and differentiation of self and family functioning predicted trait anxiety. The relationship between family functioning and trait anxiety was partially mediated by differentiation of self.
Article
Clinical Neurology
Nafisa Husein, Timothe Langlois-Therien, Bastien Rioux, Colin B. B. Josephson, Nathalie Jette, Mark R. R. Keezer
Summary: This study investigated physician opinion and practice regarding the treatment of epilepsy in older adults aged 65 years or older. The findings showed heterogeneity in therapeutic decisions and misalignment with available clinical evidence among different physician groups, indicating the need for clinical guidelines dedicated to this population.
Article
Ophthalmology
Melanie P. Napier, Kavin Selvan, Robin Z. Hayeems, Cheryl Shuman, David Chitayat, Joanne E. Sutherland, Megan A. Day, Elise Heon
Summary: The study found that LCA patients were aware of gene therapy research trials and actively sought information on advancements in ophthalmology and vision restoration. Most participants would enroll or were already enrolled in a gene-replacement therapy trial, while a minority were hesitant or unwilling to participate. Different values attributed to clinical trials influenced their willingness to participate, and intrinsic factors such as coping mechanisms, adaptation to vision loss, and resilience played a role in decision-making.
Article
Psychology, Clinical
Rebecca G. Etkin, Carla E. Marin, Wendy K. Silverman, Eli R. Lebowitz
Summary: Research has identified various factors that predict the outcome of anxiety treatment for youth. However, the impact of social functioning on treatment outcome has been rarely studied. This study examines positive social interactions and social skills as predictors of anxiety treatment outcome and finds that a higher level of social skills at baseline is associated with lower anxiety symptom severity after treatment. Additionally, the study shows that baseline reports of social skills and positive social interactions can predict remission from anxiety diagnoses, especially for girls.
BEHAVIOUR RESEARCH AND THERAPY
(2022)
Article
Clinical Neurology
Neil Kulkarni, Rachel Ayn Nageotte, Brett G. Klamer, Harold L. Rekate, Ruth E. Bristol, Travis Scharnweber, Margaret Bobrowitz, John F. Kerrigan
Summary: The purpose of this study was to determine the long-term outcome and clinical predictors for seizure freedom in patients undergoing surgical treatment for epilepsy associated with hypothalamic hamartoma (HH). The results showed that long-term seizure control following HH surgical treatment is comparable to other forms of epilepsy surgery. Late relapse and sudden unexpected death in epileptic persons (SUDEP) did occur, but in a relatively small number of treated patients.
Article
Clinical Neurology
Mehdi Khan, Aswin Chari, Kiran Seunarine, Christin Eltze, Friederike Moeller, Felice D'Arco, Rachel Thornton, Krishna Das, Stewart Boyd, J. Helen Cross, M. Zubair Tahir, Martin M. Tisdall
Summary: This study aimed to investigate the association between the proportion of resected putative seizure onset zone (SOZ) contacts and seizure outcome in children undergoing stereoelectroencephalography (SEEG)-guided resective epilepsy surgery. The results showed that in children, the percentage of resected SOZ contacts was not associated with seizure freedom after surgery.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Clinical Neurology
Graham W. Johnson, Leon Y. Cai, Saramati Narasimhan, Hernan F. J. Gonzalez, Kristin E. Wills, Victoria L. Morgan, Dario J. Englot
Summary: By developing a supervised machine learning technique using diffusion-weighted imaging, we successfully classified the seizure onset sites and surgical outcomes of patients with temporal lobe epilepsy. The results of the study demonstrated high accuracy in distinguishing patients from healthy controls and identifying seizure onset sites.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2022)
Article
Clinical Neurology
Ceren Alis, Cihan Isler, Deniz Alis, Mustafa Uzan, Cigdem Ozkara
Summary: This study aimed to identify predictive factors for seizure recurrence after epilepsy surgery in patients with lesional posterior cortex epilepsy (PCE). It was found that more than half of the patients were seizure-free at long-term follow-up, but bilateral findings on interictal EEG and gliosis were associated with recurrent seizures after surgery.
WORLD NEUROSURGERY
(2023)