Epigenetic regulation of estrogen signaling in breast cancer

A differentially methylated single CpG-site is correlated with estrogen receptor alpha transcription

(2012) Rainer W. Fürst et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The epigenetic silencing of the estrogen receptor (ER) by hypermethylation of the ESR1 promoter is seen predominantly in triple-negative breast cancers in Indian women

(2012) Jyothi S. Prabhu et al.   TUMOR BIOLOGY

Proximity ligation in situ assay for monitoring the global DNA methylation in cells

(2011) Eric Hervouet et al.   BMC BIOTECHNOLOGY

DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells

(2011) Kamaleshwar P. Singh et al.   CANCER LETTERS

Functional Activation of the Estrogen Receptor-  and Aromatase by the HDAC Inhibitor Entinostat Sensitizes ER-Negative Tumors to Letrozole

(2011) G. J. Sabnis et al.   CANCER RESEARCH

CARM1 Is an Important Determinant of ER -Dependent Breast Cancer Cell Differentiation and Proliferation in Breast Cancer Cells

(2011) M. Al-Dhaheri et al.   CANCER RESEARCH

Novel Histone Demethylase LSD1 Inhibitors Selectively Target Cancer Cells with Pluripotent Stem Cell Properties

(2011) J. Wang et al.   CANCER RESEARCH

Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells

(2011) Benjamin A.T. Rodriguez et al.   CARCINOGENESIS

H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic geneBCL2determines ERα ligand dependency

(2011) Amy Svotelis et al.   EMBO JOURNAL

Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer

(2011) Wilbert Zwart et al.   EMBO JOURNAL

Methylation specifies distinct estrogen-induced binding site repertoires of CBP to chromatin

(2011) D. G. Ceschin et al.   GENES & DEVELOPMENT

The Histone Modifications GoverningTFF1Transcription Mediated by Estrogen Receptor

(2011) Yanyan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence

(2011) Ben Zhang et al.   LANCET ONCOLOGY

Clinical implications of ERβ methylation on sporadic breast cancers in Chinese women

(2011) Lin Zhao et al.   MEDICAL ONCOLOGY

Silencing ofGSTP1, a Prostate Cancer Prognostic Gene, by the Estrogen Receptor-β and Endothelial Nitric Oxide Synthase Complex

(2011) A. Re et al.   MOLECULAR ENDOCRINOLOGY

Epigenetic Regulation of Glucose Transporter 4 by Estrogen Receptor β

(2011) Joëlle Rüegg et al.   MOLECULAR ENDOCRINOLOGY

Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis

(2011) L. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypermethylation of estrogen receptor promoter region in adult testis of rats exposed neonatally to bisphenol A

(2011) Tanvi Doshi et al.   TOXICOLOGY

Promoter methylation status and expression of estrogen receptor alpha in familial breast cancer patients

(2011) Jing Wei et al.   TUMOR BIOLOGY

PBX1 Genomic Pioneer Function Drives ERα Signaling Underlying Progression in Breast Cancer

(2011) Luca Magnani et al.   PLoS Genetics

Simultaneous CXCL12 and ESR1 CpG island hypermethylation correlates with poor prognosis in sporadic breast cancer

(2010) Edneia AS Ramos et al.   BMC CANCER

Reversibility of pre-malignant estrogen-induced epigenetic changes

(2010) Kristy Kutanzi et al.   CELL CYCLE

PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-α target gene activation by regulating lysine demethylase 1 specificity

(2010) Sujit S Nair et al.   EMBO REPORTS

Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation

(2010) Eric Hervouet et al.   Epigenetics

Bisphenol-A exposure in utero leads to epigenetic alterations in the developmental programming of uterine estrogen response

(2010) Jason G. Bromer et al.   FASEB JOURNAL

CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor   by cAMP

(2010) S. Carascossa et al.   GENES & DEVELOPMENT

Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping

(2010) P.-Y. Hsu et al.   GENOME RESEARCH

Breast cancer precursors revisited: molecular features and progression pathways

(2010) Maria A Lopez-Garcia et al.   HISTOPATHOLOGY

Xenoestrogen-Induced Regulation of EZH2 and Histone Methylation via Estrogen Receptor Signaling to PI3K/AKT

(2010) Tiffany G. Bredfeldt et al.   MOLECULAR ENDOCRINOLOGY

Disruption of Dnmt1/PCNA/UHRF1 Interactions Promotes Tumorigenesis from Human and Mice Glial Cells

(2010) Eric Hervouet et al.   PLoS One

In Utero Exposure to Diethylstilbestrol (DES) or Bisphenol-A (BPA) Increases EZH2 Expression in the Mammary Gland: An Epigenetic Mechanism Linking Endocrine Disruptors to Breast Cancer

(2010) Leo F. Doherty et al.   Hormones & Cancer

Methylation status of oestrogen receptor α-A: a predictor of prognosis in leukaemias

(2009) Jie Yao et al.   BIOSCIENCE REPORTS

Mechanisms of epigenetic silencing of the Rassf1a gene during estrogen-induced breast carcinogenesis in ACI rats

(2009) Athena Starlard-Davenport et al.   CARCINOGENESIS

Folate Supplementation Limits the Aggressiveness of Glioma via the Remethylation of DNA Repeats Element and Genes Governing Apoptosis and Proliferation

(2009) E. Hervouet et al.   CLINICAL CANCER RESEARCH

Interaction of TFAP2C with the Estrogen Receptor-  Promoter Is Controlled by Chromatin Structure

(2009) G. W. Woodfield et al.   CLINICAL CANCER RESEARCH

ChIP-Seq of ERα and RNA polymerase II defines genes differentially responding to ligands

(2009) Willem-Jan Welboren et al.   EMBO JOURNAL

Neonatal Exposure to Diethylstilbestrol Alters Expression of DNA Methyltransferases and Methylation of Genomic DNA in the Mouse Uterus

(2009) Koji SATO et al.   ENDOCRINE JOURNAL

Epigenetic Regulation of Estrogen Receptor α Gene Expression in the Mouse Cortex during Early Postnatal Development

(2009) Jenne M. Westberry et al.   ENDOCRINOLOGY

Mixed lineage leukemia histone methylases play critical roles in estrogen-mediated regulation of HOXC13

(2009) Khairul I. Ansari et al.   FEBS Journal

DNA methyltransferase expression in the human endometrium: down-regulation by progesterone and estrogen

(2009) Y. Yamagata et al.   HUMAN REPRODUCTION

Ligand-dependent Corepressor LCoR Is an Attenuator of Progesterone-regulated Gene Expression

(2009) Ana Palijan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Function of Histone Deacetylase 6 as a Cofactor of Nuclear Receptor Coregulator LCoR

(2009) Ana Palijan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requirement of Histone Methyltransferase SMYD3 for Estrogen Receptor-mediated Transcription

(2009) Hyunjung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repression of ESR1 through Actions of Estrogen Receptor Alpha and Sin3A at the Proximal Promoter

(2009) S. J. Ellison-Zelski et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone Deacetylase 7 and FoxA1 in Estrogen-Mediated Repression of RPRM

(2009) S. Malik et al.   MOLECULAR AND CELLULAR BIOLOGY

Functional Connection between Deimination and Deacetylation of Histones

(2009) H. Denis et al.   MOLECULAR AND CELLULAR BIOLOGY

Valproic acid restores ERα and antiestrogen sensitivity to ERα-negative breast cancer cells

(2009) N. Fortunati et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

BRCA1 Regulates Acetylation and Ubiquitination of Estrogen Receptor-α

(2009) Yongxian Ma et al.   MOLECULAR ENDOCRINOLOGY

Timing is everything: Order of administration of 5-aza 2′ deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity

(2008) Christine L. Hostetter et al.   CANCER LETTERS

Epithelial Progeny of Estrogen-Exposed Breast Progenitor Cells Display a Cancer-like Methylome

(2008) A. S.L. Cheng et al.   CANCER RESEARCH

DNA methylomes, histone codes and miRNAs: Tying it all together

(2008) Sònia Guil et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Estrogen regulates DNA methyltransferase 3B expression in Ishikawa endometrial adenocarcinoma cells

(2008) Min Cui et al.   MOLECULAR BIOLOGY REPORTS

Regulation of Estrogen Rapid Signaling through Arginine Methylation by PRMT1

(2008) Muriel Le Romancer et al.   MOLECULAR CELL

Cyclical DNA methylation of a transcriptionally active promoter

(2008) Raphaël Métivier et al.   NATURE

Mammalian DNA Methyltransferases: A Structural Perspective

(2008) Xiaodong Cheng et al.   STRUCTURE