SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase

The fight of the Tudor domain “Royal family” for a broken DNA throne

(2012) Frédérick A. Mallette et al.   CELL CYCLE

Small Ubiquitin-like Modifier (SUMO) Modification of Zinc Finger Protein 131 Potentiates Its Negative Effect on Estrogen Signaling

(2012) Yohan Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Damage-induced Heterogeneous Nuclear Ribonucleoprotein K SUMOylation Regulates p53 Transcriptional Activation

(2012) Federico Pelisch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Demethylase KDM5B Collaborates with TFAP2C and Myc To Repress the Cell Cycle Inhibitor p21cip (CDKN1A)

(2012) P.-P. Wong et al.   MOLECULAR AND CELLULAR BIOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage

(2012) Ismail Hassan Ismail et al.   NUCLEIC ACIDS RESEARCH

H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence

(2012) A. Chicas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Regulation of Rod Photoreceptor Homeostasis Revealed by In Vivo NRL Targetome Analysis

(2012) Hong Hao et al.   PLoS Genetics

The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor

(2011) Wu Zhou et al.   BMB Reports

Binding of the JmjC Demethylase JARID1B to LSD1/NuRD Suppresses Angiogenesis and Metastasis in Breast Cancer Cells by Repressing Chemokine CCL14

(2011) Q. Li et al.   CANCER RESEARCH

MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity

(2011) Maren H. Stindt et al.   CELL CYCLE

Regulation of Human Epidermal Stem Cell Proliferation and Senescence Requires Polycomb- Dependent and -Independent Functions of Cbx4

(2011) Nuno Miguel Luis et al.   Cell Stem Cell

Jarid1b targets genes regulating development and is involved in neural differentiation

(2011) Sandra U Schmitz et al.   EMBO JOURNAL

Epigenetic silencing of the oncogenic miR-17-92 cluster during PU.1-directed macrophage differentiation

(2011) Vit Pospisil et al.   EMBO JOURNAL

KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription

(2011) Liangqi Xie et al.   EMBO JOURNAL

BubR1 Is Modified by Sumoylation during Mitotic Progression

(2011) Feikun Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small Ubiquitin-like Modifier (SUMO) Conjugation Impedes Transcriptional Silencing by the Polycomb Group Repressor Sex Comb on Midleg

(2011) Matthew Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Jumonji/ARID1 B (JARID1B) Protein Promotes Breast Tumor Cell Cycle Progression through Epigenetic Repression of MicroRNA let-7e

(2011) Doyel Mitra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The SKP1-Cul1-F-box and Leucine-rich Repeat Protein 4 (SCF-FbxL4) Ubiquitin Ligase Regulates Lysine Demethylase 4A (KDM4A)/Jumonji Domain-containing 2A (JMJD2A) Protein

(2011) Capucine Van Rechem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interplay of Posttranslational Modifications in Sp1 Mediates Sp1 Stability during Cell Cycle Progression

(2011) Yi-Ting Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

FOXP3 Orchestrates H4K16 Acetylation and H3K4 Trimethylation for Activation of Multiple Genes by Recruiting MOF and Causing Displacement of PLU-1

(2011) Hiroto Katoh et al.   MOLECULAR CELL

PKA-dependent regulation of the histone lysine demethylase complex PHF2–ARID5B

(2011) Atsushi Baba et al.   NATURE CELL BIOLOGY

The Histone Demethylase Jarid1b (Kdm5b) Is a Novel Component of the Rb Pathway and Associates with E2f-Target Genes in MEFs during Senescence

(2011) Jeroen H. Nijwening et al.   PLoS One

Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10

(2010) Joanna Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SUMO modification selectively regulates transcriptional activity of peroxisome-proliferator-activated receptor γ in C2C12 myotubes

(2010) Sung Soo Chung et al.   BIOCHEMICAL JOURNAL

A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth

(2010) Alexander Roesch et al.   CELL

A Novel Proteomics Approach to Identify SUMOylated Proteins and Their Modification Sites in Human Cells

(2010) Frederic Galisson et al.   MOLECULAR & CELLULAR PROTEOMICS

PARP-1 Regulates Chromatin Structure and Transcription through a KDM5B-Dependent Pathway

(2010) Raga Krishnakumar et al.   MOLECULAR CELL

Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen

(2010) X. V. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PARP-1 transcriptional activity is regulated by sumoylation upon heat shock

(2009) Nadine Martin et al.   EMBO JOURNAL

Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression

(2009) D. P. Mersman et al.   GENES & DEVELOPMENT

Identification of the non-structural influenza A viral protein NS1A as a bona fide target of the Small Ubiquitin-like MOdifier by the use of dicistronic expression constructs

(2009) Sangita Pal et al.   JOURNAL OF VIROLOGICAL METHODS

RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2α

(2009) Martijn van Hagen et al.   NUCLEIC ACIDS RESEARCH

Systematic study of protein sumoylation: Development of a site-specific predictor of SUMOsp 2.0

(2009) Jian Ren et al.   PROTEOMICS

Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML

(2008) Stefan R. Weisshaar et al.   FEBS LETTERS

Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function

(2008) V. Vethantham et al.   GENES & DEVELOPMENT

SUMOylation and De-SUMOylation: Wrestling with Life's Processes

(2008) Edward T. H. Yeh   JOURNAL OF BIOLOGICAL CHEMISTRY

The Histone Demethylase KDM5b/JARID1b Plays a Role in Cell Fate Decisions by Blocking Terminal Differentiation

(2008) B. K. Dey et al.   MOLECULAR AND CELLULAR BIOLOGY

The CTCF Insulator Protein Is Posttranslationally Modified by SUMO

(2008) M. J. MacPherson et al.   MOLECULAR AND CELLULAR BIOLOGY

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY