An insight into the various regulatory mechanisms modulating human DNA methyltransferase 1 stability and function

Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation

(2012) J. Song et al.   SCIENCE

Ubiquitination/deubiquitination and acetylation/deacetylation: Making DNMT1 stability more coordinated

(2011) Qi Hong et al.   ACTA PHARMACOLOGICA SINICA

Phosphorylation of human DNMT1: Implication of cyclin-dependent kinases

(2011) Geneviève Lavoie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of mammalian DNA methyltransferases: a route to new mechanisms

(2011) Hélène Denis et al.   EMBO REPORTS

MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma

(2011) Zuping Zhang et al.   Molecular Cancer

Regulation of SNAIL1 and E-cadherin function by DNMT1 in a DNA methylation-independent context

(2011) Jesús Espada et al.   NUCLEIC ACIDS RESEARCH

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

(2011) Max Felle et al.   NUCLEIC ACIDS RESEARCH

Expression of DNMT1 and DNMT3a Are Regulated by GLI1 in Human Pancreatic Cancer

(2011) ShanShan He et al.   PLoS One

Twists and turns of DNA methylation

(2011) C. Frauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)

(2011) K. Takeshita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of DNMT1 Abundance in Epigenetic Inheritance by Acetylation, Ubiquitylation, and the Histone Code

(2011) C. Bronner   Science Signaling

Regulation of DNA methyltransferase 1 by interactions and modifications

(2011) Weihua Qin et al.   Nucleus

DNA methyltransferases and methyl-binding proteins of mammals

(2010) J. Lan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1

(2010) Sha Zhao et al.   ARTHRITIS AND RHEUMATISM

Coordinated Chromatin Control: Structural and Functional Linkage of DNA and Histone Methylation

(2010) Xiaodong Cheng et al.   BIOCHEMISTRY

The biological significance of substrate inhibition: A mechanism with diverse functions

(2010) Michael C. Reed et al.   BIOESSAYS

Dysregulation of p53/Sp1 Control Leads to DNA Methyltransferase-1 Overexpression in Lung Cancer

(2010) R.-K. Lin et al.   CANCER RESEARCH

Smad Signaling Is Required to Maintain Epigenetic Silencing during Breast Cancer Progression

(2010) P. Papageorgis et al.   CANCER RESEARCH

Structure and Function of Mammalian DNA Methyltransferases

(2010) Renata Zofia Jurkowska et al.   CHEMBIOCHEM

Molecular and Enzymatic Profiles of Mammalian DNA Methyltransferases: Structures and Targets for Drugs

(2010) F. Xu et al.   CURRENT MEDICINAL CHEMISTRY

SET7/9 mediated methylation of non-histone proteins in mammalian cells

(2010) Sriharsa Pradhan et al.   Epigenetics

Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1

(2010) Jinfeng Huang et al.   HEPATOLOGY

Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1

(2010) Weihua Qin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

(2010) W. Pan et al.   JOURNAL OF IMMUNOLOGY

Linking cell signaling and the epigenetic machinery

(2010) Helai P Mohammad et al.   NATURE BIOTECHNOLOGY

A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability

(2010) Pierre-Olivier Estève et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

(2010) J. Song et al.   SCIENCE

DNMT1 Stability Is Regulated by Proteins Coordinating Deubiquitination and Acetylation-Driven Ubiquitination

(2010) Z. Du et al.   Science Signaling

Molecular marks for epigenetic identification of developmental and cancer stem cells

(2010) Samir Kumar Patra et al.   Clinical Epigenetics

SUMOylation enhances DNA methyltransferase 1 activity

(2009) Bongyong Lee et al.   BIOCHEMICAL JOURNAL

Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2′-deoxycytidine and DNA-demethylation

(2009) S. K. Patra et al.   BIOCHEMISTRY-MOSCOW

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1

(2009) R. Garzon et al.   BLOOD

Rethinking how DNA methylation patterns are maintained

(2009) Peter A. Jones et al.   NATURE REVIEWS GENETICS

Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

(2009) P.-O. Esteve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CXXC Domain of Human DNMT1 Is Essential for Enzymatic Activity

(2008) Mihika Pradhan et al.   BIOCHEMISTRY

Mammalian Cytosine DNA Methyltransferase Dnmt1: Enzymatic Mechanism, Novel Mechanism-Based Inhibitors, and RNA-directed DNA Methylation

(2008) Zeljko Svedruzic   CURRENT MEDICINAL CHEMISTRY

Ras regulation of DNA-methylation and cancer

(2008) Samir Kumar Patra   EXPERIMENTAL CELL RESEARCH

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

(2008) Jing Wang et al.   NATURE GENETICS

Protein demethylation required for DNA methylation

(2008) Hans-Rudolf Hotz et al.   NATURE GENETICS

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

Reading and writing DNA methylation

(2008) Albert Jeltsch   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

(2008) Roberta Benetti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY